1/ At Valence Labs, @recursionpharma.bsky.social's AI research engine, we’re focused on advancing drug discovery outcomes through cutting-edge computational methods
Today, we're excited to share our vision for building virtual cells, guided by the predict-explain-discover framework 🧵
(1/5) The Molecular Machine Learning Conference (MoML) is back @mila-quebec.bsky.social this June 18th.
Join researchers advancing machine learning, molecular modeling, and therapeutic design.
Tickets are free for students.
Register Today: portal.ml4dd.com/events/molec...
I’ll write up some more detailed thoughts and takeaways once I’m back in Montréal and have a minute!
Had a great time at the Ascona 2025 conference on benchmarking in biology! Thanks to @markrobinsonca.bsky.social and all other organizers.
I’m grateful for the opportunity to present our @polarishub.io platform at the historic and beautiful Monte Verità (“Mount Truth”) venue.
Look at that view! 😍
🚀 Antiviral Challenge Results! 🚀
After weeks of competition, and nearly 400 submissions, the antiviral challenge has concluded!
Thank you to all of our participants. Each submission came with a report — check out the full leaderboard and find more details 👇
✨ Symposium session reveal ✨ AI-assisted Drug Discovery: Benchmarking the Field - Gustavo Stolovitzky and @caswognum.nl will explore how benchmarking can drive better, more reliable AI tools for drug discovery and biomedicine. Learn more and register here: conscience.ca/symposium2025
In case you missed it!
Join us tomorrow to hear @peterskrinjar.bsky.social talk about 🌹 Runs N' Poses 🌹! Curious to hear your thoughts on how to keep up with benchmarking in this field.
⚡ The intermediate leaderboard for the antiviral challenge is now live!
👀 See how you placed: antiviral.polarishub.io
The challenge officially ends on March 10th, but there's one last leaderboard update before the final results.
Submit before midnight on Feb 26th! polarishub.io/competitions
Volgens mij ga je hierin voorbij aan het doel om elkaar beter te begrijpen. De nadruk ligt daarmee op het woord, niet de intentie.
Ik ben oprecht benieuwd hoe je hier over denkt als journalist.
Zet mij in ieder geval aan het denken!
Verrijkend gesprek! Leuk!
Ik hoor een interessante tegenstelling: Enerzijds blijkt taal voor interpretatie vatbaar, maar anderszijds discussiëren jullie specifieke woordkeuze.
Taal doet er toe - zeker als journalist - maar ik vraag me hardop af of je woordkeuze zo niet té veel macht geeft…
We’re hosting @peterskrinjar.bsky.social for a webinar to discuss his latest paper “Have protein co-folding methods moved beyond memorization?”!
Join live on Feb 21st at 11 AM ET. Register here: us06web.zoom.us/webinar/regi...
Explore Runs N’ Poses on Polaris today: polarishub.io/benchmarks/p...
Endless views and impressive cloudscapes!
#photography #lions #kenya #maasaimara #simba
We’re extremely excited to host Runs N’ Poses on Polaris!
The authors show how current co-folding methods struggle to generalize beyond ligand poses in their training data.
Explore the benchmark: polarishub.io/benchmarks/p...
Explore the dataset: polarishub.io/datasets/pli...
Would be cool to see how OpenFold does on this new benchmark! 👀
(And the science, of course!)
Love the logo and name! 🎸
And if you're curious, you can learn more about what we actually mean by "ML-ready" in our recent blog: polarishub.io/blog/reprodu...
A few weeks back I got in touch with @ninjani.bsky.social about creating a "ML-ready" version of a PLINDER dataset. Excited to release a first attempt at this!
💬 Let us know how we did
discord.gg/uGCZB7PXmX
bsky.app/profile/dkoe...
New leaderboard on @polarishub.io for Runs 'N Poses! 🎸
Anyone has any protein-ligand co-folding methods laying around they would like to put to the test?
polarishub.io/benchmarks/p...
Great work @peterskrinjar.bsky.social @jeeberhardt.bsky.social @torstenschwede.bsky.social @ninjani.bsky.social
bsky.app/profile/pola...
Excited to share our latest preprint evaluating AlphaFold3, Boltz-1, Chai-1 and Protenix for predicting protein-ligand interactions, featuring our newly introduced benchmark dataset 🌹Runs N’ Poses🌹!
www.biorxiv.org/content/10.1...
🧵👇 (1/n)
@polarishub.io has a benchmarking API which ensures you use the exact same split and metrics as everyone else. See the screenshot.
We're aiming to serve as a source of truth for machine learning in drug discovery. For context, see: polarishub.io/blog/reprodu...
Would love to hear your feedback!
Interesting!
This would be a nice “baseline” to have for the associated Polaris benchmark. polarishub.io/benchmarks/b....
With the increased activity on the platform recently, things have been breaking in new ways (sorry Windows users!), but I love it!
It shows that people are actually using Polaris! Our team is fixing issues as soon as we can and it’s helping us improve the overall robustness. Keep ‘m coming! 🏗️
Big milestone for @polarishub.io. We merged our first external contribution, thanks to @fastprop.bsky.social! 🎉
github.com/polaris-hub/...
#opensource #benchmarking #ml #drugdiscovery
🚨 Extension Alert: The intermediate leaderboard submission deadline for the antiviral challenge has been extended to midnight on February 7th!
Don't miss this chance to see how you stack up against other participants! Submit your results today: polarishub.io/competitions
With @polarishub.io we early on decided to purposefully restrict the flexibility of our datasets and benchmarks.
We understand that this can be frustrating at times, but we believe it’s an important step to improve reproducibility.
Our team is here to help if you need support! Reach out on Github.
💡Have questions about the data behind the antiviral challenge?💡
This week, @asapdiscovery.bsky.social and @omsf.io are hosting 3 virtual office hour sessions with the experimentalists behind the data!
RSVP here: docs.google.com/forms/d/e/1F...
Only a few days left to submit your predictions for the first, intermediate leaderboard.
We’ve got an incredibly passionate team on standby to help solve any issues you may run into and we’d love to hear your feedback.
🧑💻 Github: github.com/polaris-hub/...
💬 Discord: discord.gg/vBFd8p6H7u
