Hey Mathieu, c‘est jamais fun mais on est déjà entrain de préparer la soumission pour un autre journal. Ça va marcher d’une manière ou d’une autre :)
Hey Mathieu, c‘est jamais fun mais on est déjà entrain de préparer la soumission pour un autre journal. Ça va marcher d’une manière ou d’une autre :)
I have also developed novel algorithms, using opencv, for the quantification of condensates properties in microscropy pictures. Check my github for more information! github.com/mas-gu/llps_...
I have created the video showcasing the PDIA6 condensate dynamics and function using Blender and the Molecular Nodes module! Visualizing science like never before. #Blender #MolecularNodes @bradyajohnston.bsky.social
Our results show PDIA6 condensates recruit key chaperones (BiP, ERdj3, Grp94) to enhance proinsulin folding & prevent misfolding, driven by Ca²⁺. This opens new perspectives for tackling protein misfolding diseases like diabetes! @natcellbio.nature.com
Thrilled to share my first corresponding author paper as a project leader in @hillerlab.bsky.social Amazing work from first author @annaleder.bsky.social We discovered multi-chaperone condensates in the ER that revolutionise the current vision of protein folding!
www.nature.com/articles/s41...
Shreyan Datta has demonstrated exceptional performance in our lab. I highly recommend him to anyone seeking an outstanding PhD candidate!
Great work from @annaleder.bsky.social in my chaperone sub-group at the Hiller Lab!
Two postdoctoral positions in the group of Dr. Malene R. Jensen at the Institute for Structural Biology in Grenoble, France, protein kinase (MAPK) cell signaling pathways (incl NMR, X-ray crystallography and cryo-electron microscopy) www.jensen-nmr.fr #NMRjobs #NMRchat #NMR 🧲
Merci Mathieu!
Thanks, glad you like it!
It’s fully adaptable to study other nucleotide-driven machines, dissecting functional cycles, regulation, and cofactor effects with unprecedented resolution. #MolecularMachine
Applied to the Hsp70 BiP NBD, in-cyclo NMR reveals all 11 microscopic kinetic rates of ATP binding, hydrolysis & product release — showing ADP·Pi release, not ATP hydrolysis, is the rate-limiting step controlling the cycle duration.
Thrilled to share our new method in-cyclo NMR that lets us watch molecular machines in action — decoding molecular machine kinetics with atomic precision and exceptional time resolution in one go! 🚀 Check it out: doi.org/10.1038/s414... #NMR #StructuralBiology
Great to be back at the @enc-conference.org #ENCISMAR2025 . Enjoying the conference and the beautiful wildlife.