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Parc de Recerca Biomèdica de Barcelona

@prbb.org

We are the largest biomedical science hub in the south of Europe, by the beach in Barcelona. Recerca biomèdica amb vistes | @researchmar.bsky.social @crg.eu @melisupf.bsky.social @embl.org @isglobal.org @ibe-barcelona.bsky.social @fpmaragall.bsky.social

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Latest posts by Parc de Recerca Biomèdica de Barcelona @prbb.org

Three more weeks to apply and join us in Barcelona!

Help us understanding how oocytes regulate proteostasis and fertility!

Find here more detailed information on the call:
recruitment.crg.eu/content/jobs...

Please spread around your communities!

09.03.2026 13:04 👍 8 🔁 6 💬 1 📌 0
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From impact factor to disinformation: Jordi Camí on the integrity crisis in scientific publishing - El·lipse PRBB Director General Jordi Camí explores the integrity crisis in scientific publishing: fraud, disinformation, generative AI, and reform paths.

Papers are still at the centre of how science is shared and assessed today. But the classic evaluation model based on bibliometric output is losing credibility, while new forms of fraud grow and more structured disinformation initiatives appear.

🟠 https://goo.su/RXIOQ

#Science #PRBB

09.03.2026 17:03 👍 1 🔁 1 💬 0 📌 0
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Research is also built by sharing experiences along the way.

🤔 What advice would you give to someone considering a career in research?

#InternationalWomensDay #PRBB #WomenInScience #WomenInSTEM

09.03.2026 09:23 👍 1 🔁 0 💬 0 📌 0
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🟣 From teamwork and perseverance to wellbeing and adaptability, their experiences offer different perspectives on what a career in research can look like.

09.03.2026 09:23 👍 1 🔁 0 💬 1 📌 0
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🤔 Thinking about a career in research?

On #InternationalWomensDay, women from the #PRBB centres shared reflections, advice and lessons learned from their journeys in science.

Here are some voices from the #PRBBCommunity 👇

#WomenInScience

09.03.2026 09:23 👍 3 🔁 1 💬 1 📌 0
Evolutionary emergence and preservation of microproteins encoded by upstream ORFs The analysis of ribosome profiling (Ribo-Seq) data has provided evidence that many eukaryotic mRNAs contain translated upstream or downstream ORFs (uORFs/dORFs), but the biological significance of this translation activity remains, for the most part, unknown. One of the principal limitations has been the lack of Ribo-Seq data from several closely related species, precluding the identification of cases in which translation is phylogenetically conserved. Here, by combining Ribo-Seq data from 100 different experiments, we identify 2,332 translated uORFs and 1,008 translated dORFs in S. cerevisiae, which result in microproteins that tend to be highly hydrophobic or positively charged. To study their phylogenetic conservation, we have generated Nanopore direct RNA sequencing data, together with Ribo-Seq data, from six additional Saccharomyces species, spanning an evolutionary period of around 16 million years. We have identified 195 translated S. cerevisiae uORFs that are also translated in other Saccharomyces species; these uORFs are translated at levels comparable to the main coding sequence and display signatures of purifying selection at the level of the encoded microproteins. In contrast, dORFs are translated at very low levels and they are rarely conserved, suggesting much more limited microprotein functionalization. We have also discovered that uORF translation is associated with the formation of alternative transcript isoforms encompassing the region containing the uORFs but not the main protein coding sequence, implying that some microproteins can be produced independently of the main protein product. This work significantly advances our understanding of how initially pervasive uORF translation can result in new microproteins, providing many new candidates for further functional studies. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, https://ror.org/0472cxd90, 101052538 Ministerio de Ciencia, Innovación y Universidades, PID2021- 122726NBI00, PGC2018-094091- B-I00, PID2022-136939OBI00, CEX2024-001431-M, MICIU/AEI/10.13039/501100011033 Generalitat de Catalunya, https://ror.org/01bg62x04, 2021SGR00042, 2021SGR00176

New preprint from the group!

Here we use Nanopore dRNA and Ribo-Seq data from multiple yeast species to discover tens of highly conserved microproteins encoded by uORFs in polycistronic transcripts/alternative isoforms. @prbb.org @grib-barcelona.bsky.social

www.biorxiv.org/content/10.6...

08.03.2026 19:13 👍 7 🔁 4 💬 0 📌 0
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⚡️¿Sabías que en el PRBB la mayor parte del consumo de energía proviene de los laboratorios?

Nuevas medidas de eficiencia, monitorización y mejoras en la infraestructura ayudan a reducir su impacto.

 Avanzamos hacia un PRBB más eficiente y sostenible.
👉https://tuit.cat/vuhbg

07.03.2026 15:02 👍 1 🔁 0 💬 0 📌 0
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✨ @montse_barcelo, autora de esta imagen, nos comparte su fascinación por el PRBB.
📸 ¡Descubre la historia que hay detrás de esta foto!

👉 Léela aquí: https://tuit.cat/6iqMp

07.03.2026 10:01 👍 1 🔁 0 💬 0 📌 0
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⚡️Sabies que al PRBB la major part del consum d'energia ve dels laboratoris?

Noves mesures d’eficiència, monitoratge i millores d’infraestructura ajuden a reduir-ne l’impacte.

♻️ Avancem cap a un PRBB més eficient i sostenible.
👉Llegir aquí: https://tuit.cat/6911o

06.03.2026 15:03 👍 0 🔁 0 💬 0 📌 0

cc @researchmar.bsky.social @crg.eu @melisupf.bsky.social @embl.org @isglobal.org @ibe-barcelona.bsky.social @fpmaragall.bsky.social

06.03.2026 11:59 👍 0 🔁 0 💬 0 📌 0
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For #InternationalWomensDay, we’re looking at the presence of women across the #PRBB centres.

Women make up 60% of the PRBB community, and in 2024 they became the majority among principal investigators (PIs) for the first time.

#WomenInScience

06.03.2026 11:59 👍 1 🔁 1 💬 1 📌 0
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✨ La @montse_barcelo, autora d’aquesta imatge, ens explica la seva fascinació pel PRBB.
📸 Descobriu la història que hi ha darrere aquesta foto!

👉 Llegiu-ho aquí: https://tuit.cat/7IBOa

06.03.2026 11:02 👍 1 🔁 0 💬 0 📌 0
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¿Tiene el modelo actual de publicación científica los días contados? 🤔

📢 Jordi Camí lo explica en su charla “Del factor de impacto a la desinformación”
👉 https://tuit.cat/Sza1C
@hospitaldelmar.bsky.social @fpmaragall.bsky.social @melisupf.bsky.social @isglobal.org @crg.eu @ibe-barcelona.bsky.social

06.03.2026 09:02 👍 0 🔁 0 💬 0 📌 0
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🚨JOB ALERT🚨PLEASE SPREAD and RT

Searching for a motivated Master’s student @bokelab.bsky.social @crg.eu @prbb.org to investigate how proteostasis in oocytes influences dormancy and fertility.

Reach out to me (adriano.bolondi@crg.es) to join us in sunny Barcelona!

See details below👇

05.03.2026 14:21 👍 6 🔁 15 💬 0 📌 2
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⚡️ Did you know that most of the PRBB’s energy consumption comes from laboratories?

New efficiency measures, energy monitoring, and infrastructure upgrades are helping reduce its impact.

♻️ Moving towards a more efficient and sustainable PRBB.
👉 https://tuit.cat/8xVeQ

05.03.2026 15:15 👍 0 🔁 0 💬 0 📌 0
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✨ Montse Barceló Riera, the photographer behind this image, shares her fascination with the PRBB.
📸 Discover the story behind this photo!

👉 Read it here: https://tuit.cat/gn8Iq

05.03.2026 12:02 👍 0 🔁 0 💬 0 📌 0
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Té el model actual de publicació científica els dies comptats? 🤔📚

📢 Jordi Camí ho explica a la seva xerrada “Del factor d’impacte a la desinformació”
👉 https://tuit.cat/USgsK

@hospitaldelmar.bsky.social @fpmaragall.bsky.social @melisupf.bsky.social @isglobal.org @crg.eu @ibe-barcelona.bsky.social

05.03.2026 09:03 👍 0 🔁 0 💬 0 📌 0
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Is the current scientific publishing model on its way out?
🤔📚

📢 Jordi Camí addresses this topic in his talk “From Impact Factor to Misinformation”
👉 https://tuit.cat/W83hN
@hospitaldelmar.bsky.social @ibe‑barcelona.bsky.social @fpmaragall.bsky.social  @melisupf.bsky.social @isglobal.org @crg.eu

04.03.2026 17:38 👍 1 🔁 0 💬 0 📌 0
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Busques un desafiament estimulant i un ambient de treball enriquidor? el #PRBB és el teu lloc! 😎

Consulta les nostres #ofertesfeina 👉https://www.prbb.org/carrera.php#Ofertas-empleo

🔬 #Genòmica 🧬 #BiologiadeSistemes 🧠 #Neurociència 🌍 #SalutGlobal 💊 #RecercaTranslacional 🧪 #FeinaRecerca #ScienceJobs

04.03.2026 14:50 👍 0 🔁 0 💬 0 📌 0
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New preprint from
@novoalab.bsky.social !

Which tRNAs are used by ribosomes during translation?

We introduce tRIBO-seq, a nanopore method to sequence ribosome-associated tRNAs and track how the active tRNA pool changes across stress conditions.

www.biorxiv.org/content/10.6...

Thread 👇

04.03.2026 09:25 👍 35 🔁 13 💬 2 📌 1
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Learn analytical and creative tools that will help you to frame and reframe complex problems.

For all the #PRBBCommunity!

ℹ️ & registrations: intervals.prbb.org/courses/10

02.03.2026 10:40 👍 0 🔁 0 💬 0 📌 0
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Sistemas complejos - El·lipse El investigador Ricard Solé nos habla de cómo comportamientos "emergen" de las interacciones entre los elementos de los sistemas complejos, desde las neuronas que forman recuerdos hasta las hormigas que construyen nidos.

Algunos patrones globales no pueden explicarse solo por las propiedades de las unidades individuales. 🌐

 Ricard Solé @melisupf.bsky.social  explora los sistemas complejos: desde las colonias de hormigas 🐜 hasta el cerebro humano. 🧠
👉

02.03.2026 09:03 👍 0 🔁 0 💬 0 📌 0
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Sistemes complexos - El·lipse L'investigador Ricard Solé ens parla sobre com comportaments "sorgeixen" de les interaccions col·lectives entre els elements que formen els sistemes complexos; des de les neurones que formen records fins a les formigues que construeixen nius.

Alguns patrons globals no s’expliquen només per les propietats de cada unitat. 

Ricard Solé @melisupf.bsky.social  ens parla dels sistemes complexos: des de les colònies de formigues 🐜 fins al cervell humà 🧠.

 

01.03.2026 08:31 👍 2 🔁 0 💬 0 📌 0
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Complex systems: more than a sum of parts - El·lipse Researcher Ricard Solé tell us about how behaviors "emerge" from collective interactions between elements in complex systems; from neurons forming memories to ants building nests.

Some global patterns cannot be explained solely by the properties of individual units. 🌐

Ricard Solé @melisupf.bsky.social  explores complex systems: from ant colonies 🐜 to the human brain. 🧠

👉

28.02.2026 08:32 👍 3 🔁 1 💬 0 📌 0
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#CiènciaAlDescobert | Què és l'epigenètica?

🧬 "Epi", en grec, significa "damunt". Per això s'anomena epigenètica a l'estudi de tot allò que està "damunt" dels gens.

Sense modificar el codi de l’ADN, l’epigenètica pot alterar l’expressió dels nostres gens.

T'ho expliquem! 👉 https://tuit.cat/JDits

27.02.2026 10:30 👍 2 🔁 0 💬 0 📌 0
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CRG BioBusiness School 2026: del laboratorio al mercado - El·lipse Inscripciones abiertas para la CRG BioBusiness School 2026, curso online de cinco días sobre emprendimiento científico y transferencia tecnológica.

👩‍🔬 Un curso de negocios hecho por científicos, para científicos
🫰 CRG BioBusiness School 2026, un programa online de 5 días para ayudar a los investigadores en ciencias de la vida a llevar sus ideas “del laboratorio al mercado”. 📈
@crg.eu 
Más info: https://tuit.cat/0lt40"

27.02.2026 08:31 👍 0 🔁 0 💬 0 📌 0
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CRG BioBusiness School 2026: from lab to market - El·lipse Applications are open for the CRG BioBusiness School 2026, a five-day online course introducing life scientists to entrepreneurship, technology transfer and start-up venture building.

👩‍🔬Un curs de negoci fet per científics, per a científics

🫰CRG BioBusiness School 2026 arrenca amb un programa online de 5 dies per ajudar investigadors en ciències de la vida a portar les seves idees “del laboratori al mercat”. 📈
@crg.eu 

Més info:

26.02.2026 09:04 👍 1 🔁 0 💬 0 📌 0
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CRG BioBusiness School 2026: from lab to market - El·lipse Applications are open for the CRG BioBusiness School 2026, a five-day online course introducing life scientists to entrepreneurship, technology transfer and start-up venture building.

👩‍🔬 A business course by scientists, for scientists

🫰 CRG BioBusiness School 2026 kicks off with a 5 day online program to help life science researchers take their ideas “from the lab to the market.” 📈
@crg.eu 

More info:

25.02.2026 15:42 👍 0 🔁 0 💬 0 📌 0
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#JobOffer
MELIS is looking for 2 Bioinformatics Research Technicians to join our department:
💻 R, Python, STAR, DESeq2
⏰ Deadline: Mar 18
Apply: recruitment.melis@upf.edu (Ref. MELIS-PSR-INDF-2026-06)
Details: www.upf.edu/documents/d/...

20.02.2026 11:15 👍 8 🔁 5 💬 0 📌 2
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Un estudi detalla les causes per les que el consum de cannabis empitjora el tractament contra les psicosis "Els pacients que continuen consumint cànnabis van pitjor", explica el psiquiatra del hospital del Mar Daniel Bergé

🧠Consum de cànnabis i primers episodis psicòtics: més inflamació cerebral i possible menor resposta als antipsicòtics, segons un estudi de l’@researchmar.bsky.social publicat a Molecular Psychiatry de @nature.com.
📰Article a @elperiodico.com: www.elperiodico.cat/ca/ser-felic...

23.02.2026 14:09 👍 1 🔁 1 💬 0 📌 0