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Posts tagged #ASNBasicSci

Fans of and experts in tubule physiology have many questions for our junior investigator presenters. #ASNBasicSci #KidneyWk

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Join @Nephro_Sparks Schiessl and I for a tour of basic science posters now - meeting at Communities lounge!

#ASNBasicSci #KidneyWk #selfitis

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Trying something different this #KidneyWk: going to some sessions covering topics in which I have zero expertise. Currently in senescent cell session. What is seno_lysis? Not sure but will let you know when I find out! #ASNBasicSci

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Alright, nephrons, ICYMI: this happened at the first annual #KidneyWk #ASNBasicSci forum for young investigators! @dhekidney (Jedi) battles @arohan_s (Vader) over the distal nephron. You don’t want to miss next year’s @ASNKidney Clash!

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.@dhekidney battles @arohan_s over the role of WNKs in distal nephron! #KidneyWk #ASNBasicSci #battleoverdistalnephron #nephrology

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The battle continues! #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@arohan_s: We identified DCNL4 that regulates complex in ICs #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@dhekidney: mechanism? #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@arohan_s: WNK1 mutation driving DCT transcription might be offset by WNK1 IC activity. #KidneyWk #ASNBasicSci #battleoverdistalnephron

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Jedi comes back swinging on rebuttal: “I haven’t seen that data ... which are PRELIMINARY!” Burn! #KidneyWk #ASNBasicSci #battleoverdistalnephron

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#KidneyWk #ASNBasicSci #battleoverdistalnephron #vader

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@arohan_s strikes again: IC-specific deletion of WNK1 leads to hyperK #KidneyWk #ASNBasicSci #battleoverdistalnephron

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Dietary K loading upregulates L-WNK1 in ICs. Sabers clash. #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@arohan_s: how does K get into intercalated cells? NKCC1. NKCC1 activated by WNK pathway. Jedi frowns. #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@arohan_s pushes Jedi down the intercalated cell path #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@arohan_s draws red light saber: yes, transcripts are in DCT, but RNA is not functional protein! #KidneyWk #ASNBasicSci #battleoverdistalnephron

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<deep Vader breathing> #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@arohan_s strikes back: there is more than DCT #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@dhekidney goes in for kill #KidneyWk #ASNBasicSci #battleoverdistalnephron

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Vader looks worried that altering DCT changes potassium secretory pathways #KidneyWk #ASNBasicSci #battleoverdistalnephron

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DCT-specific NCC activation caused full FHHt phenotype (@dhekidney swinging light saber by citing @PAWellingMD) #KidneyWk #ASNBasicSci #battleoverdistalnephron

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Jedi pulls out potassium card. And that thiazide drug that led to complete control of WNK diseases in human and mouse. #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@dhekidney: Kidney-specific WNK1 80x more highly expressed in DCT; other WNKs also enriched there. #KidneyWk #ASNBasicSci #battleoverdistalnephron

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@dhekidney hits first: WNK kinases are most highly expressed along DCT and disruption of ion transport mimics FHHt; effects outside DCT mostly secondary. #KidneyWk #ASNBasicSci #battleoverdistalnephron

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Watching with anticipation: epic #ASNBasicSci battle between past mentor @dhekidney and rogue Vader son @arohan_s is about to commence! #KidenyWk

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Afternoon sessions of the #ASNBasicSci forum for young investigators begin with “Meet the @NIDDKgov O’Brien Centers.” Everyone is learning what makes each center a unique and valuable resource for kidney research. @NU_Nephrology makes its O’Brien debut! #KidneyWk @SusanQuaggin

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Great fun moderating rapid communications session with @Nephro_Sparks at the #ASNBasicSci forum for young investigators! #KidneyWk #Selfie

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Lakhia also shows miR-214 promotes accumulation of M2 macrophages. The binding targets of the miR are involved in inflammation. @UTSWNephrology #KidneyWk #ASNBasicSci

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@GentzonHallMD of @DukeKidney presents his work on genetic basis of cholesterol transport in podocytes, with potential therapeutic implications for FSGS! #KidneyWk #ASNBasicSci

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@SilviaFerre_it takes the stage to discuss molecular mechanisms of the unfolded protein response in AKI! #KidneyWk #ASNBasicSci

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