A graphic with a quote and modified figure from the linked Nature Communications paper, “Limitations of acyclovir and identification of potent HSV antivirals using 3D bioprinted human skin equivalents” (doi: 10.1038/s41467-025-64245-w). It features Figure 2A, a schematic illustrating the following: “Dermis equivalents were 3D printed onto the apical side of transwell inserts...Keratinocytes were pipetted onto the apical surface of the dermis. In the submerged model, the tissues were infected at the apical surface. In the ALI model, tissues were brought to ALI and then infected at the basolateral surface.” Also a quote from a NCATS article published on January 27, 2026: “This collaborative research showed that the bioprinted 3-D skin tissue model closely replicates the structure and layered organization of human skin and that HSV infects these cells the same way it infects people.”
There is currently no cure for #HSV, and patients can develop resistance to the drug used to manage symptoms.
But thanks to NCATS' 3D Tissue Bioprinting Program, scientists now have the best model yet for testing new treatments.
ncats.nih.gov/news-events/...
#3Dprinting #bioprinting #virosky 🧪