#CD38

Pur-Ther

@pur-ther.bsky.social

2 months ago

CD38-specific nanobody-based bispecific antibody recruiters (BARs) redirect complement-dependent cytotoxicity toward multiple myeloma cells - Scientific Reports Bispecific antibody recruiters (BARs) are an innovative class of immunotherapeutics that redirect endogenous antibodies to tumor cells. BARs comprise a tumor-binding and an antibody-binding module, en...

Amazing publication from the THUNDER lab at UKE, which is also part of our consortium!
It's about a new class of engagers for the treatment of multiple myeloma.🧑‍🔬🤯🤩 #sciencerocks #CD38 #nanobody
www.nature.com/articles/s41...

@tubsmedbiotech.bsky.social

2 months ago

Resolving the Interference of Anti‐CD38 Antibodies on Blood Compatibility Assays Using CD38 “Baitbodies” Approach Blood transfusion safety depends on swift blood compatibility testing. Alloantibodies recognizing these blood group antigens determine blood compatibility, and the transfusion of incompatible blood c...

A CD38 "baitbody" to support safe blood products for multiple myeloma patients receiving Daratumumab and Isatuximab.
onlinelibrary.wiley.com/doi/full/10....

#baitbody, #daratumumab, #felzartamab, #isatuximab, #transfusionmedicine, #antibody, #fusionprotein, #bloodcompatability, #CD38, #MM

ASH Clinical News

@ashclinicalnews.bsky.social

5 months ago

An analysis of #genomic data from patients with #MultipleMyeloma #MMsm showed that loss of #CD38 expression can occur after treatment with #antiCD38 antibodies, arising in 20% of patients analyzed, with three cases exhibiting a loss of both copies: ow.ly/IfmE50WXc76 #HemeSky #OncSky

@jyves94.bsky.social

8 months ago

FDA grants accelerated approval to linvoseltamab-gcpt for relapsed or FDA grants accelerated approval to linvoseltamab-gcpt for relapsed or refractory multiple myeloma

La #FDA des #USA accorde une #FastTrack 🚀 au #Linvoseltamab 💊, un engageur #Bispécifique des lymphocytes T #CD3 dirigé vers #BCMA, pour le #MyélomeMultiple 🩸 R/R, qui ont reçu ≥4 LOT auparavant, y compris un IP, un #IMiD et un #AnticorpsMonoclonal anti- #CD38
www.fda.gov/drugs/resour...

Transplant International

@transpl-int.bsky.social

8 months ago

THE MAY ISSUE IS ONLINE!!

The antobody-mediated rejection of the kidney has a new target!!

Check it out here: shorturl.at/Vb0DN

#may #issue #antibody #rejection #kidney #CD38 #target @esottransplant.bsky.social

Second Ave. Sagas

@2avesag.as

9 months ago

In #CD38, I endorse the incumbent Shahana Hanif. Another strong voice for transportation, she supported the Arrow Linen rezoning and City of Yes. She is facing a primary challenger funded, in part, by Republican donors.

A View From The Hook - Adam Armstrong

@viewfromthehook.bsky.social

12 years ago

Congratulations to @Carlos4Council! #CD38 "@DanWiley1: Carlos Menchaca wins City Council, Sunset Park/Red Hook! http://t.co/JfK27oEORY"

A View From The Hook - Adam Armstrong

@viewfromthehook.bsky.social

12 years ago

Bad form "@BrooklynInsides: Councilwoman Sara gonzalez refuses to debate challenger @Carlos4Council tonight." www.gothamgazette.com/index.php/gotham-votes/4... #CD38