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Posts tagged #CILIA

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Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome.

Congratulations to Lucile Boutaud, Sophie Thomas and colleagues @institutimagine.bsky.social ! #cilia #ciliopathies

onlinelibrary.wiley.com/doi/10.1111/...

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Our next afternoon meeting is organized by @alexbnmrh.bsky.social on Wednesday March 18 @institutimagine.bsky.social ! Happy to see you soon there...
#cilia #ciliopathies #flagella

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Video

Zooplankton larvae shoot up in the water column when exposed to high pressure.

Mediated by special pressure-sensory photoreceptors.

From our paper on the mechanism of barotaxis.

https://elifesciences.org/articles/94306
#cilia #plankton #neuroscience

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📣Short perspective article in #Cytoskeleton introducing the Czech 🇨🇿 #Cilia #research community (from now on officially termed 🪧CiliaNet CZ 💪).
👇
onlinelibrary.wiley.com/doi/10.1002/...

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#cilia peeps 🤯

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PoL – Physics of Life | Team | PoL Groups | Benjamin Friedrich Physics of Life: Discover new paradigms for understanding life and deepen our knowledge of living biological matter

Looking for a theory partner for an #HFSP project? #morphogenesis in cells and tissues, #chemotaxis, #cilia? Feel free to reach out! Deadline for letters of intent 26.03.2026.
physics-of-life.tu-dresden.de/team/pol-gro...

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An inducible multiciliated cell line resolves proteome dynamics and identifies CDK7 as a conserved regulator. New study from Camille Boutin @camboutin.bsky.social, Laurent Kodjabachian @ibdm.bsky.social @univ-amu.fr and colleagues: rupress.org/jcb/article/...

#Cilia #Technology #Development

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🧪 🧫 Photoreceptors depend on exquisitely organised cilia, with disruptions in microtubule regulation compromising retinal health. Beyond providing molecular diagnoses to affected families, this work deepens our understanding of ciliary biology, and highlights why fundamental research matters.
#Cilia

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Preview
Bacteria deliver a microtubule-binding protein into mammalian cells to promote colonization Pathogenic Bordetella bacteria use protein adhesins to infect the ciliated respiratory epithelia of vertebrate hosts. In this work, we show that the filamentous hemagglutinin FhaB adhesin of Bordetell...

SPOILER: Bordetella sticks to #cilia

Bacteria deliver a microtubule-binding protein into mammalian cells to promote colonization | Science www.science.org/doi/10.1126/...

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The figure shows staining of mouse embryos with X-gal to highlight Ttc21b in whole-mount embryos (panels A-D,H) or after sectioning (panels E-G,I-N). Boxed areas in panel E are shown magnified in panels F and G, boxed areas in panels I and L are shown magnified in panels J and M. Arrows indicate specific areas of lacZ expression.

The figure shows staining of mouse embryos with X-gal to highlight Ttc21b in whole-mount embryos (panels A-D,H) or after sectioning (panels E-G,I-N). Boxed areas in panel E are shown magnified in panels F and G, boxed areas in panels I and L are shown magnified in panels J and M. Arrows indicate specific areas of lacZ expression.

Rebekah Niewoehner, Rolf Stottmann & co found that pathogenic Ttc21b variants, the primary #cilia gene, contribute to primary #microcephaly, with homozygous #mouse mutants showing severe #microcephaly due to impaired neural progenitor proliferation and differentiation.

Read doi.org/10.1242/dmm....

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Weekending using shaders from @blenderkit.bsky.social
Concept inspired by @bradyajohnston.bsky.social
Dynein arms — the ATP-powered engines behind ciliary motion.
#Dynein #Cilia #Axoneme #MolecularBiology #StructuralBiology #CryoEM #ProteinStructure #Biophysics #Blender3D #SciArt #BioArt

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Great to see our paper on light-intensity dependent swimming patterns in #Chlamydomonas out now in Phys Rev Lett. as an Editors' suggestion! With a nice commentary by @philipcball.bsky.social.

Chlamy actively modulate the beat planes of their #cilia!
journals.aps.org/prl/abstract... #protistsonsky

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Great afternoon with Jihane and Nikita meeting with young French high school students to discuss what we are doing in the @hkd-l.bsky.social lab on #cilia and #ciliopathies as part of the @cilia-ai.bsky.social project!
Many thanks to @cerclefser.bsky.social for the organization of #declics

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Video of the syncytial nerve net that regulates the gravisensory balancer ciliated cells in the ctenophore aboral organ (red dots - synapses)

https://elifesciences.org/articles/108420#video1 #cilia #neuroscience

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Together we tried to understand why the #Xenopus embryo have motile #cilia.
In the second part of the workshop, they played at being researchers and tried to guess the stages of embryos using binocular.

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@camboutin.bsky.social, Kodjabachian et al. @ibdm.bsky.social describe an inducible multiciliated cell line well suited for advanced #microscopy and #proteomic approaches. The study provides a detailed proteomic profiling of MCC during their differentiation. rupress.org/jcb/article/...

#Cilia

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Proud and excited to share our work with the community! Helen @helenfoster.bsky.social Foster et al. study how #cilia axonemes are built. 👀 Don't miss the gorgeous and insightful movies by @margotriggi.bsky.social, they really show our discoveries in full action!

www.biorxiv.org/content/10.6...

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Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

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🟡🇻🇪En Venezuela dicen:
#LosQueremosDeVuelta
#Maduro
#Cilia

Un mes de impunidad.

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Preview
a woman in a long black dress is walking down a foggy street . ALT: a woman in a long black dress is walking down a foggy street .

The once-in-a-lifetime comedic queen Catherine O'Hara had situs inversus

#cilia #ciliopathy

www.usatoday.com/story/entert...

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A protein complex in the extreme distal tip of vertebrate motile cilia controls their organization, length, and function - Nature Communications Here they combine in vivo imaging with proteomics to characterize a protein complex comprised of Ccdc78 and Ccdc33 that acts at the extreme distal tip of 9 + 2 motile cilia to control tip architecture...

Cilia alert! Stoked to have the new paper from Juyeon Hong about a new domain at the extreme distal tip of motile cilia! (The EDT, y'all!) It's out now @natcomms.nature.com.
Check it out!
#cilia

www.nature.com/articles/s41...

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Photo of Nayeli Reyes-Nava

Photo of Nayeli Reyes-Nava

Meet Nayeli Reyes-Nava, 1st author of #EditorsChoice paper with @edwardmarcotte.bsky.social, @jbwallingford.bsky.social & co who used #Xenopus to study #Cilia motility disturbances in primary ciliary dyskinesia #PCD

Interview & article:
doi.org/10.1242/dmm....
doi.org/10.1242/dmm....

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A new map of human cilia reveals unexpected protein diversity Tiny organelles hold big surprises. A new study published in Cell reveals unexpected diversity in cilia, with implications for biology and medicine.

A new map of human #cilia, published in Cell, reveals unexpected protein diversity 🧪

“Mapping cilia at this scale shows just how adaptable these structures are,” says Jan Hansen (@stanford.edu /SciLifeLab/KTH).

Learn more ↓
www.scilifelab.se/news/a-new-m...

@cellpress.bsky.social

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Mark your calendar for the best #cilia conference out there! 👇

Our very own Susan @dutcherlab.bsky.social is presenting one of the keynotes!! 🙌

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So excited about this #cilia conference at the beautiful Lake Maggiore, Italy. We have a great list of speakers so far, and two amazing keynote lectures.

Get your abstracts ready, registration will open soon! 👇🏼

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𝗠𝗲𝗲𝘁 𝗼𝘂𝗿 𝗸𝗲𝘆𝗻𝗼𝘁𝗲 𝘀𝗽𝗲𝗮𝗸𝗲𝗿𝘀 𝗳𝗼𝗿 #𝗖𝗶𝗹𝗶𝗮𝟮𝟬𝟮𝟳!

We are grateful for their participation and look forward to welcoming the cilia community on 8-12, March 2027.

Wishing you all a happy and inspiring 2026! 🎉

#Cilia #Milan

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Y nos fuimos a la Plaza Bolivar de #Caracas a realizar las cartas de Amor para nuestro Presidente Constitucional Nicolás #Maduro y la Primera Combatiente #Cilia Flores, secuestrados por #EEUU el pasado #3enero. Próximamente les compartiré el video.
#BringThemBack #Venezuela

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Amazing to hold @lottepedersen.bsky.social & my @jcellsci.bsky.social Special Issue on #Cilia and #Flagella in all its glossy glory & muscle-engaging brain-boosting weight! So much fabulous content from the community! Fab cover @centriolelab.bsky.social 🥰🥰 journals.biologists.com/jcs/pages/ci...

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Ooh! A few of my favorite things #Cilia #Signaling #L/RPatterning #NodalFlow #Biophysics- congratulations @vermotlab.bsky.social @jvermot.bsky.social! 🤩

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We close with Ruhee Dere new roles for #EpigeneticEraser KDM4A at remodelling #centrosomes and maintaining #cilia, all enzyme activity dependent and non-transcriptional- what is the PTM target? So many questions... #UKCili2026 7/8

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