#Clae

@ophthalmology.bsky.social

1 month ago

Analysis of tear inflammatory proteins following Low-Level light therapy in dry eye disease patients Low-level light therapy (LLLT) in combination with intense pulsed light (IPL) has been shown to improve clinical signs and symptoms of dry eye disease (DED), as well as tear inflammatory protein levels. However, the therapeutic mechanism of LLLT as a stand-alone treatment remains unclear. This single-arm pilot study aimed to determine the impact of LLLT alone on tear protein levels in patients with DED.

Ophthopedia Update: Analysis of tear inflammatory proteins following Low-Level light therapy in dry eye disease patients: Low-level light therapy (LLLT) in combination with intense pulsed light (IPL) has been shown to improve clinical signs and symptoms of dry eye disease… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Editorial Board

Ophthopedia Update: Editorial Board #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Lacrimal gland Ga-68 PSMA-11 PET/CT radiomic profile: a potential novel imaging biomarker in dry eye disease This study aimed to investigate the relationship between texture analysis parameters of lacrimal gland activity and dry eye disease (DED) in participants undergoing Gallium-68 labelled Prostate-Specific Membrane Antigen ligand Positron Emission Tomography / Computed Tomography ([68 Ga]Ga-PSMA-11 PET/CT) imaging for prostate cancer (PCa).

Ophthopedia Update: Lacrimal gland Ga-68 PSMA-11 PET/CT radiomic profile: a potential novel imaging biomarker in dry eye disease: This study aimed to investigate the relationship between texture analysis parameters of lacrimal gland activity and dry eye disease (DED) in… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Comprehensive assessment of tear film dynamics in pediatric vernal keratoconjunctivitis using a novel non-invasive device (MYAH) To objectively evaluate tear film parameters in children diagnosed with vernal keratoconjunctivitis (VKC) using the MYAH device, and to compare the findings with those of healthy controls.

Ophthopedia Update: Comprehensive assessment of tear film dynamics in pediatric vernal keratoconjunctivitis using a novel non-invasive device (MYAH): To objectively evaluate tear film parameters in children diagnosed with vernal keratoconjunctivitis (VKC) using the MYAH… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Eyes on the Journal: how curiosity shaped a career in clinical research Since taking up the role of BCLA president, I have been reflecting on how scientific curiosity, often sparked by a single paper or an unanswered research question, became the driving force behind my clinical research career. A similar theme was explored in my Presidential Address, titled Eyes on the Journey (London, June 2025), where I outlined how key innovations in contact lenses and developments in education helped shape a career rooted in curiosity and collaboration. While that address described a broader professional journey, this editorial focusses on the role the BCLA’s research journal, Contact Lens and Anterior Eye (CLAE), has played in my career and how CLAE continues to nurture that same spirit for eye care professionals around the world.

Ophthopedia Update: Eyes on the Journal: how curiosity shaped a career in clinical research: Since taking up the role of BCLA president, I have been reflecting on how scientific curiosity, often sparked by a single paper or an unanswered research question, became the… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Corrigendum to “Scleral lens landing zone toricity and tear exchange” [Contact Lens Anterior Eye 49(1) (2025) 102571] The following references contained errors in the originally published manuscript.

Ophthopedia Update: Corrigendum to “Scleral lens landing zone toricity and tear exchange” [Contact Lens Anterior Eye 49(1) (2025) 102571]: The following references contained errors in the originally published manuscript. #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Impact of orthokeratology lens decentration on axial length growth in Chinese myopic children: A meta-analysis Orthokeratology (OK) lenses have become a prevalent intervention for myopia control. However, lens decentration, a frequent complication, may influence the efficacy of myopia control. The aim of this study was to systematically assess the impact of OK lens decentration on axial length growth (ALG) in Chinese myopic children through a meta-analysis.

Ophthopedia Update: Impact of orthokeratology lens decentration on axial length growth in Chinese myopic children: A meta-analysis: Orthokeratology (OK) lenses have become a prevalent intervention for myopia control. However, lens decentration, a frequent complication,… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Tendency to obtain written informed consent in clinical applications of contact lenses Notwithstanding contact lenses extensive clinical application, complications particularly in the absence of adequate hygiene and education remain a concern. The objective of this study was to evaluate physicians’ propensity to obtain written informed consent prior to the prescription of contact lenses, and to investigate the factors associated with this practice.

Ophthopedia Update: Tendency to obtain written informed consent in clinical applications of contact lenses: Notwithstanding contact lenses extensive clinical application, complications particularly in the absence of adequate hygiene and education remain a concern. The… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Clinical efficacy of induced epiphora by punctal plugging on refractory dry eye disease with ocular surface Damage: Randomized sham-controlled trial To evaluate the efficacy of induced epiphora by punctal plug on refractory dry eye disease (DED) with ocular surface damage.

Ophthopedia Update: Clinical efficacy of induced epiphora by punctal plugging on refractory dry eye disease with ocular surface Damage: Randomized sham-controlled trial: To evaluate the efficacy of induced epiphora by punctal plug on refractory dry eye disease (DED) with… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Ophthopedia Update: Vision-related quality of life in highly myopic children undergoing orthokeratology treatment: To compare the vision-related quality of life (VRQoL) of highly myopic children before and after one-year orthokeratology (ortho-k) treatment, and between… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

2 months ago

Exploring the potential for microbial transfer from exhaled breath to the ocular surface: a comparative analysis of respiratory and ocular microbiota Respiratory microbes typically enter the body via the nose and mouth, but transmission through the ocular surface-nasolacrimal duct route remains poorly understood. This study investigated the microbiota of exhaled breath, conjunctiva, and anterior nares in healthy individuals to assess the potential for microbial transfer from exhalations to the ocular surface.

Ophthopedia Update: Exploring the potential for microbial transfer from exhaled breath to the ocular surface: a comparative analysis of respiratory and ocular microbiota: Respiratory microbes typically enter the body via the nose and mouth, but transmission through the… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

3 months ago

Editorial Board The content on this site is intended for healthcare professionals. All content on this site: Copyright © 2025 Elsevier Inc., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.

Ophthopedia Update: Editorial Board #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

4 months ago

In vitro antibacterial efficacy and antibiofilm activity on contact lenses of a new ophthalmic spray containing Biosecur® citrus extract (Oftasecur®) To investigate the in vitro antimicrobial activity of a new commercial ocular spray containing 0.2% Biosecur® citrus extract (Oftasecur®) against Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli and test its efficacy in preventing biofilm formation on etafilcon A and senofilcon A contact lenses.

Ophthopedia Update: In vitro antibacterial efficacy and antibiofilm activity on contact lenses of a new ophthalmic spray containing Biosecur® citrus extract (Oftasecur®): To investigate the in vitro antimicrobial activity of a new commercial ocular spray containing 0.2%… #eye #Ophthalmology #CLAE

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Litix Legal

@litixlegal.bsky.social

4 months ago

Litix Legal’s own Ryan Hurley was recently featured in a panel discussing the use of alternative dispute resolution within the cannabis industry.

Members of the Arizona Bar can access this webinar here 💻 ➡️ lnkd.in/gERC27Ep

#cannabislaw #disputresolution #ArizonaLawyer #CLAE #AZBAR

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Ophthopedia

@ophthalmology.bsky.social

4 months ago

A survey of contact lens users: Adherence to care guidelines and knowledge of microbial keratitis risk Contact lenses are widely used for cosmetic and refractive purposes. Proper usage and hygiene are critical to preventing ocular complications like microbial keratitis (MK). This study aims to assess the level of awareness and practices regarding contact lens use and hygiene among a sample population.

Ophthopedia Update: A survey of contact lens users: Adherence to care guidelines and knowledge of microbial keratitis risk: Contact lenses are widely used for cosmetic and refractive purposes. Proper usage and hygiene are critical to preventing ocular complications like… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

4 months ago

Contact lens discomfort and associated conditions: Definitions and disambiguation relative to dry eye disease Terminology used in relation to contact lens discomfort, and its associated conditions has proliferated, leading to confusion and misuse. This short article demonstrates that the lexicon can be reduced to four terms, which are sufficient to describe the field. These are contact lens discomfort (CLD), contact lens associated dry eye (CLADE), contact lens induced dry eye (CLIDE) and dry eye disease (DED). Definitions for these conditions are clarified and their diagnostic pathways described. Exclusive use of these defined terms is recommended to avoid future misunderstanding, simplify clinical differential diagnosis, maximise treatment efficacy and facilitate the interpretation of research outputs by promoting characterisation of homogenous study groups.

Ophthopedia Update: Contact lens discomfort and associated conditions: Definitions and disambiguation relative to dry eye disease: Terminology used in relation to contact lens discomfort, and its associated conditions has proliferated, leading to confusion and misuse.… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

4 months ago

Letter to the editor Thank you to Dr. Parth Aphale et al for their interest in our paper and the points they have raised.

Ophthopedia Update: Letter to the editor: Thank you to Dr. Parth Aphale et al for their interest in our paper and the points they have raised. #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

4 months ago

Standardized evaluation of orthokeratology lens fitting status assisted by deep learning algorithm Aims to develop a standardized evaluation method based on the YOLOv8n object detection algorithm, with the goal of quantitatively assessing the displacement of orthokeratology lenses (OK_lenses) and objectively evaluating their fitting status under fluorescein staining conditions.

Ophthopedia Update: Standardized evaluation of orthokeratology lens fitting status assisted by deep learning algorithm: Aims to develop a standardized evaluation method based on the YOLOv8n object detection algorithm, with the goal of quantitatively assessing the… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

5 months ago

The relationship between relative peripheral refraction and axial length elongation in myopic children wearing orthokeratology lenses using a novel wide-angle multispectral refraction topographer To investigate the peripheral retinal relative defocus in myopic children wearing orthokeratology (OK) lenses and evaluate its relationship with the efficacy of myopia control.

Ophthopedia Update: The relationship between relative peripheral refraction and axial length elongation in myopic children wearing orthokeratology lenses using a novel wide-angle multispectral refraction topographer: To investigate the peripheral retinal relative defocus… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

5 months ago

Influence of baseline characteristics on subjective improvement of dry eye after intense pulsed light therapy To identify baseline clinical signs and symptoms associated with response to intense pulsed light (IPL) combined with meibomian gland expression in dry eye disease (DED), and to develop machine learning (ML) models for individualized outcome prediction.

Ophthopedia Update: Influence of baseline characteristics on subjective improvement of dry eye after intense pulsed light therapy: To identify baseline clinical signs and symptoms associated with response to intense pulsed light (IPL) combined with meibomian gland… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

5 months ago

Effects of ambient illuminance and mobile phone screen brightness on tear film stability, visual fatigue, and blink patterns during reading This study aimed to investigate the impacts of different ambient illuminance and screen brightness conditions on tear film stability, visual fatigue, and blink patterns during mobile phone reading.

Ophthopedia Update: Effects of ambient illuminance and mobile phone screen brightness on tear film stability, visual fatigue, and blink patterns during reading: This study aimed to investigate the impacts of different ambient illuminance and screen brightness conditions… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

5 months ago

Comparison of different methods to image the tear film before and during contact lens wear To evaluate the repeatability and compare non-invasive tear breakup time (NIBUT) and tear film lipid layer thickness (TFLLT) measurements obtained using subjective (Keeler Tearscope-Plus) and objective (Oculus Keratograph 5M and LipiView II Interferometer) instruments before and during soft contact lens (CL) wear.

Ophthopedia Update: Comparison of different methods to image the tear film before and during contact lens wear: To evaluate the repeatability and compare non-invasive tear breakup time (NIBUT) and tear film lipid layer thickness (TFLLT) measurements obtained using… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

6 months ago

IMI-global trends in myopia management attitudes and strategies in clinical practice – A nine-year review Surveys in 2015, 2019, and 2022 identified a high level of eye care practitioner activity and concern about pediatric myopia, reflected by an uptake of appropriate control techniques. This research provided updated information, examining global trends from 2015 to 2024.

Ophthopedia Update: IMI-global trends in myopia management attitudes and strategies in clinical practice – A nine-year review: Surveys in 2015, 2019, and 2022 identified a high level of eye care practitioner activity and concern about pediatric myopia, reflected by an… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

6 months ago

Scleral shell prostheses in patient care: A survey of eyecare clinicians in New Zealand Research to guide scleral shell practice is sparse with minimal evidence-based information available about indications and contraindications for shell wear, or the ideal wear and maintenance regimes. New Zealand optometrists, ophthalmologists and ocular prosthetists were surveyed to gauge current understanding.

Ophthopedia Update: Scleral shell prostheses in patient care: A survey of eyecare clinicians in New Zealand: Research to guide scleral shell practice is sparse with minimal evidence-based information available about indications and contraindications for shell wear, or the… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

6 months ago

Randomized contralateral eye study of myopia control between aspheric multifocal soft contact lens and orthokeratology in children This study aimed to compare myopia progression in children wearing an aspheric multifocal contact lens and an orthokeratology (OrthoK) lens.

Ophthopedia Update: Randomized contralateral eye study of myopia control between aspheric multifocal soft contact lens and orthokeratology in children: This study aimed to compare myopia progression in children wearing an aspheric multifocal contact lens and an… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

6 months ago

Diagnostic accuracy in dry eye: Insights into clinical and artificial intelligence limitations To evaluate the agreement and performance of four large language models (LLMs)—ChatGPT-3.5, ChatGPT-4.0, Leny-ai, and MediSearch—in diagnosing and classifying Dry Eye Disease (DED), compared to clinician judgment and Dry Eye Workshop-II (DEWS-II) criteria.

Ophthopedia Update: Diagnostic accuracy in dry eye: Insights into clinical and artificial intelligence limitations: To evaluate the agreement and performance of four large language models (LLMs)—ChatGPT-3.5, ChatGPT-4.0, Leny-ai, and MediSearch—in diagnosing and… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

6 months ago

Reliability and readability of online patient information for contact lens wearers Contact lenses (CL) are an attractive option for the correction of refractive errors including myopia, hyperopia, astigmatism and presbyopia, with an estimated 140 million CL wearers worldwide [1]. Although severe ocular complications related to CL wear are very rare, with an incidence of 2.0 cases of microbial keratitis per year per 10,000 disposable soft CL wearers [2], they may lead to partial and irreversible visual loss. To ensure the safety of CL wear, users are required to follow a set of maintenance instructions, usually provided by optometrists or other eye care professionals during the initial CL fitting process.

Ophthopedia Update: Reliability and readability of online patient information for contact lens wearers: Contact lenses (CL) are an attractive option for the correction of refractive errors including myopia, hyperopia, astigmatism and presbyopia, with an estimated 140… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

6 months ago

Dehydration kinetics of soft contact lenses: The hidden impact of early wear In contact lens (CL) wear, maintaining adequate CL hydration is essential to prevent ocular dryness and associated discomfort. In this context, dehydration of worn Etafilcon A and Kalifilcon A CLs hydrated by natural tears was monitored using an in-vitro gravimetric method. A kinetic model was applied to derive the water kinetics coefficient, which emerged as a reliable indicator of the on-eye hydration state and water diffusion mechanisms. A significant reduction in water content and a tendency from a polymer-hindered water diffusion toward free diffusion were observed after just five minutes of wear, suggesting a rapid initial adaptation to the ocular environment that alters the material resistance to water evaporation.

Ophthopedia Update: Dehydration kinetics of soft contact lenses: The hidden impact of early wear: In contact lens (CL) wear, maintaining adequate CL hydration is essential to prevent ocular dryness and associated discomfort. In this context, dehydration of worn Etafilcon… #eye #Ophthalmology #CLAE

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Ophthopedia

@ophthalmology.bsky.social

6 months ago

Proteomic analysis of tear fluid: Comparative short-term effects of scleral lenses and rigid corneal lenses wear in ametropic healthy adults The aim of this study was to evaluate the effect of scleral lenses (SLs) on the ocular surface of healthy individuals and explore potential molecular changes in the tear fluid reservoir associated with this form of contact lens.

Ophthopedia Update: Proteomic analysis of tear fluid: Comparative short-term effects of scleral lenses and rigid corneal lenses wear in ametropic healthy adults: The aim of this study was to evaluate the effect of scleral lenses (SLs) on the ocular surface of healthy… #eye #Ophthalmology #CLAE

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Retreat Clothing Abergavenny

@retreatclothing.bsky.social

6 months ago

Winter '25 Clae styles just arrived. We love the heritage Romare boot 🔥 available instore and online retreat-clothing.co.uk #Abergavenny #winter #newstock #Clae #sneakers #boots #footwear #mensfashion

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Posts tagged #Clae