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Posts tagged #CoreOutcomeSets

Screenshot of text and a table.

Chen et al., “The most common patient-centred outcomes were quality of life, satisfaction or patient experience, self-management or self-care, depression or mental health, physical function or exercise capacity, cost-effectiveness, cognitive function, adherence, empowerment and hospitalisations.”

The table then presents the outcomes from the core outcome sets and the number of studies in Chen et al. (2026) that report this outcome (max. n=25)

(Health-related) Quality of Life	    9
Mental Health	    4
Mortality	
Adverse Events	    1
Development of New Comorbidity	0
Health-risk Behaviour	0
Adherence to Treatment	    2
Health-care Cost (out of pocket)	    4

Number of studies based on those reported in Chen et al. (Tables 2 & 3), so it may be that some of the less usual outcomes such as health-care cost were not extracted by the team of the systematic review. On the other hand, “cost” is coded inclusively as not all studies assessed out-of-pocket cost (not relevant in all health care systems).

The table also codes which outcomes are drawn from which core outcome set, which was unfortunately difficult to describe - here are the references to the sets:
1 Smith et al. (2018). The Annals of Family Medicine, 16, 132–138.
2 “Intervention” in Vidyasagaran et al. (2024). BMJ Global Health, 9, Article e015120.
3 “Prevention” in Vidyasagaran et al. (2024). BMJ Global Health, 9, Article e015120.

Screenshot of text and a table. Chen et al., “The most common patient-centred outcomes were quality of life, satisfaction or patient experience, self-management or self-care, depression or mental health, physical function or exercise capacity, cost-effectiveness, cognitive function, adherence, empowerment and hospitalisations.” The table then presents the outcomes from the core outcome sets and the number of studies in Chen et al. (2026) that report this outcome (max. n=25) (Health-related) Quality of Life 9 Mental Health 4 Mortality Adverse Events 1 Development of New Comorbidity 0 Health-risk Behaviour 0 Adherence to Treatment 2 Health-care Cost (out of pocket) 4 Number of studies based on those reported in Chen et al. (Tables 2 & 3), so it may be that some of the less usual outcomes such as health-care cost were not extracted by the team of the systematic review. On the other hand, “cost” is coded inclusively as not all studies assessed out-of-pocket cost (not relevant in all health care systems). The table also codes which outcomes are drawn from which core outcome set, which was unfortunately difficult to describe - here are the references to the sets: 1 Smith et al. (2018). The Annals of Family Medicine, 16, 132–138. 2 “Intervention” in Vidyasagaran et al. (2024). BMJ Global Health, 9, Article e015120. 3 “Prevention” in Vidyasagaran et al. (2024). BMJ Global Health, 9, Article e015120.

A #SysReview exploring impacts of community-based interventions for adults with #multimorbidity on clinical and patient-reported outcomes (25 studies):
bmjpublichealth.bmj.com/content/4/1/...

Quick comparison of identified outcomes with the two central #CoreOutcomeSets 👇

#HRQOL #Psychometrics

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Preview
Methodological guidance for incorporating lived experience in the early stages of core outcome set development: a scoping review protocol - Trials Introduction One challenge facing researchers is the heterogeneity of outcomes measured in health research. Researchers can reduce outcome heterogeneity and ensure relevance of outcomes by using a Cor...

Thrilled to share my first PhD publication is now out in Trials! 🎉
Open access protocol: “Incorporating lived experience in the long-list generation stage of Core Outcome Set development.”
🔗 doi.org/10.1186/s130...

#PhDResearch #OpenAccess #CoreOutcomeSets
@hrb-tmrn.bsky.social

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Recruitment flyer for a PhD study at the University of Limerick on Core Outcome Set (COS) development. The flyer headline reads “Study Recruitment! Core Outcome Set Development.” It asks:

Have you been involved in developing a COS as a researcher, clinician, patient, carer, family member, or otherwise?

The study aims to understand how people with lived experience are included in the early stages of COS development.

Participants will be invited to take part in a one-on-one interview.

Contact: Livingston.Marci@ul.ie
.
Logos: University of Limerick, Education and Health Sciences.
Approval: EHSREC (Ref No: 2025_05_10_EHS).
Design elements include abstract shapes and an illustration of a person sitting at a desk with a laptop and coffee.

Recruitment flyer for a PhD study at the University of Limerick on Core Outcome Set (COS) development. The flyer headline reads “Study Recruitment! Core Outcome Set Development.” It asks: Have you been involved in developing a COS as a researcher, clinician, patient, carer, family member, or otherwise? The study aims to understand how people with lived experience are included in the early stages of COS development. Participants will be invited to take part in a one-on-one interview. Contact: Livingston.Marci@ul.ie . Logos: University of Limerick, Education and Health Sciences. Approval: EHSREC (Ref No: 2025_05_10_EHS). Design elements include abstract shapes and an illustration of a person sitting at a desk with a laptop and coffee.

Have you been involved in developing a Core Outcome Set? Researchers, clinicians, patients, or carers—we want to hear from you! Help us explore how those with lived experience are included in the COS development process.
#CoreOutcomeSets #PPI #ClinicalTrials
Contact:
📧 Livingston.Marci@ul.ie

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Arun Sanyal giving the Curtis Meinert Keynote @ #SCT2025 talks us through the use of Desirability of Outcome Ranking (DOOR) in liver trials. Makes a suggestion for pan-specialty #CoreOutcomeSets to facilitate DOOR integration in evidence synthesis for intersecting clinical contexts.

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