After a long time I remade my office Zoom background - and I really like it - especially the Texas #CureIPF license plate. And yes, one day we’ll get there!
#CurePF4All
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#CureIPF
Latest posts tagged with #CureIPF on Bluesky
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Posts tagged #CureIPF
Oscillometry is all the rage in lung function these days 🫁
If you're not quite sure what it is, this editorial might help!
#openaccess @bmj.com @ats-clinicalprobs.bsky.social #ILD #CurePF #CureIPF
bmjopenrespres.bmj.com/content/13/1...
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Is fibroblast proliferation important in pulmonary fibrosis? Finally an answer - great paper by the super team of Christopher Molina,Tatsuya Tsukui, and Dean Sheppard
#זScienceMatters
#CureIPF
www.jci.org/articles/vie...
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Finally a good animal model of human Pulmonary Fibrosis?
The Ferret bleomycin shares IPF features including: patchy distribution of fibrotic foci, honeycomb cyst-likes, ⬆️ blood MMP7, KL6, presence aberrant epithelial basaloid cells.
Kudos DrsWu, Liu & team
#CureIPF
www.nature.com/articles/s41...
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Screen shot of title page
The Impact of Pulmonary Fibrosis on Sex and Sexual Function - A Multinational Mixed Methods Study
Just out in ERJ and led by Dr. Na'ama Avitzur
A 🧵👇
(key take-away 👉 sex matters to patients with PF and their disease impacts this)
#OpenAccess #CurePF #CureIPF
publications.ersnet.org/content/erj/...
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Yesterday, the U.S. FDA approved Jascayd (nerandomilast) to treat IPF. This is the first IPF new therapy approved in more than a decade.
Congratulations to all our patients & yes, better drugs are on the way!!
Great day for the #CureIPF community!!
#ScienceMatters
www.fda.gov/drugs/news-e...
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Fascinating work on the regulation of telomere length - molecular clocks we all have in our cells controlling aging and disease.
Emerging evidence of their role pulmonary fibrosis.
#CureIPF
#Telomeres
@elife.bsky.social
@rcsi.bsky.social
@kaminskimed.bsky.social
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Great work by Dr Aoife Carolan from our group at @rcsi.bsky.social
RCSI showing data from our familial pulmonary fibrosis clinic.
- 1 in 5 patients have a family memeber with lung fibrosis.
- 1 in 5 of these patients have a single suspected gene.
#CureIPF
@europeanrespsoc.bsky.social
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However, another study highlighting the disappearing treatment effect! Check the placebo vs Pirfenidone groups! 😳😳 we really need better drugs to #CureIPF
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Phenomenal result! FIRST positive 52 week study of inhaled therapy in #IPF. Benefits were independent of background therapy! 🤩
Along with Nerandomilast this shows importance of cAMP/PDE4 pathways in fibrosis & opens door 4 other therapies targeting these pathways!
#FutureLooksBright #CureIPF
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Looks like telomere dysfunction is complex in mice and people
- needs more investigation and great science.
#Telomeres
#CureIPF
🧪
🧬
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Really cool: "Myeloid-mesenchymal crosstalk drives ARG1-dependent profibrotic metabolism via ornithine in lung fibrosis" - myeloid cells made ornithine ➡️ proline ➡️ collagen in fibroblast.
Kudos Drs Yadav, Bhattacharya & team
www.jci.org/articles/vie...
@jclinical-invest.bsky.social #CureIPF
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I’m sorry to hear about your FIL ❤️
Pulmonary fibrosis can be devastating. All of us working in the field (including our amazing patient partners) hope that the diagnostic tools, treatments, and overall management/support improve with the work we are doing 🙏 #CureIPF #CurePF
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Woohoo! Latest preprint from the lab describing how fibroblasts can use alanine to bypass glutamine requirements for differentiation and ECM production. It's a lovely example of metabolic flexibility with implications for how we study cell metabolism. Shout out to Fei Li, who led this work! #cureipf
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Delighted to give a talk at the Vermont Lung Stem Cell Conference last week.
Also got to visit with @kottond.bsky.social, Finn Hawkins, Joe Kaserman, and Kostas Alysandratos - all legends of the lung regeneration field at the CReM Boston University
@crem-boston.bsky.social
#CureIPF
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Thank you!! 🙏🙏😊😊
And yes, just like old #MedTwitter #MedSky #AcademicSky #CureIPF
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Finally out! The first AI regenerative model applied to IPF & PCLS single nuclear sequencing data is out & it works!!
See 🧵 below
and paper here
www.nature.com/articles/s41...
#CureIPF
#ScienceMatters
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Another piece in the puzzle of telomere biology disorders and pulmonary fibrosis - well done to the Tzfati and @kaminskimed.bsky.social teams.
Beautiful paper!
#CureIPF
#MedSky
#SciSky
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This 👇🏽of course was proposed by the great Moises Selman and Annie Pardo in 2006 in their classic "Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers" review!
#AnnieAndMoisesWereRight
#CureIPF
www.atsjournals.org/doi/full/10....
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Deeply grateful to all contributors; Current or former #KaminskiLab members; generous collaborators: Takis, Ivan, Melanie, Jun, the FORMIDABLE @KU_Leuven
team - Wim & Bart; and special 👏🏽👏🏽 to #SuperDuo : Schupp & Adams‼️
Fin.
#SchuppAndAdams
#CureIPF
#ScienceMatters
www.biorxiv.org/content/10.1...
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5/n Taken together, our results shift the paradigmatic view of alveolar epithelial cells in IPF from ‘innocent bystanders’ to 'drivers of disease' - maybe positioning Aberrant Basaloid Cells as potential targets for cell-based therapies
#CureIPF
#PrecisionMedicine
www.biorxiv.org/content/10.1...
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1/n
Using snRNAseq we identify a previously undiscovered population of alveolar epithelial cells in IPF - Alveolar Intermediate (ATi) cells - they share features of ATI, ATII and Aberrant Basaloid cells but also have their own distinct features.
#ATi
#CureIPF
www.biorxiv.org/content/10.1...
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Congratulations Dr Schweikert. You have achieved so much over the last years - work that will help patients with pulmonary fibrosis.
#CureIPF
#iPSC
@anjaschweikert.bsky.social
@ozakimari.bsky.social
@rcsi.bsky.social
@ilfa-ireland.bsky.social
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Wow! What a day for #CureIPF & #ATS2025! First positive drug trial in 10 years in IPF!! Treatment with Nerandomilast -> ⬇️FVC decline compared to placebo in patients on antifibrotics or untreated. Kudos Drs Richeldi and Wijsenbeek and #FibroneerIPF team!!! www.nejm.org/doi/full/10....
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Kicking off my first day at #ATS2025 looking forward to catching up with the pulmonary fibrosis research community and hearing the latest data! 🫁 #cureIPF
@atscommunity.bsky.social
@atsearlycareer.bsky.social
@ats-rcmb.bsky.social
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What is familial pulmonary fibrosis?
Who needs a genetic test?
What is a telomere?
Read more in Dr. Aoife Carolan's case published in ERS Breathe this month.
#CureIPF
#ILD
#Telomere
@rcsi.bsky.social
@tissueengdublin.bsky.social
@ilfa-ireland.bsky.social
publications.ersnet.org/content/brea...
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Outstanding address by President of the Association of American Physicians Dr. Paul Noble at the joint meeting Meeting of Physician Scientist Societies - AAP/ASCI/APSA. He spoke about inspiration, achievement and his career in #CureIPF
#ScienceMatters
#PatientsMatter
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See above #CureIPF #Cure4IPF #pulmonaryfibrosis (what about prevent IPF? 😀)
@ipfdoc.bsky.social @kerrijohannson.bsky.social @lucillapiccari.bsky.social
www.cell.com/cell/fulltex...
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Video explainer of the new Patient Stem Cell Discovery Core in RCSI @rcsi.bsky.social & Beaumont Hospital.
With patients like David Crosby we aim to find treatments for pulmonary fibrosis and cystic fibrosis.
🧪
#CureIPF
#iPSC
#CF
Supporting work by
@erc.europa.eu
@researchireland.bsky.social
HRB
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Screen shot of the article title in Annals ATS and authorship
#ILDSky #CureIPF #CurePF
Nintedanib for SSc-ILD at Scleroderma centres in the US.
Not one 🫁 MD on this paper 👀
Are Rheumatologists treating/managing ILD at your centres?
@jskim8223.bsky.social @ipfdoc.bsky.social @tkulkarni.bsky.social @istamina.bsky.social
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