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Latest posts tagged with #DepMap on Bluesky

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Posts tagged #DepMap

Interesting to note his observations on the small-world nature of buffering networks, and that he relates it to my post doc work on target distances in combination therapies! (I didn’t tell him to say that 😄) #networks #DepMap

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Session 2 kicks off with Manuel Kaulich showing exciting new work on nuclear mRNA processing masking CRISPR KO phenotypes - so new it’s not yet published, so no photo this time #CancerResearch #CRISPR #DepMap

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The R2 platform : Democratizing bioinformatics through an easily accessible public online software platform for non-experts in the field of Genomics

r2platform.com

#genomics #datascience #expertise #fair #public #science #bioinformatics #nocode #tcga #gtex #depmap

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The R2 platform : Democratizing bioinformatics through an easily accessible public online software platform for non-experts in the field of Genomics

r2.amc.nl

#genomics #datascience #expertise #fair #public #science #bioinformatics #nocode #tcga #gtex #depmap

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Explore parameter sweeps of data driven embeddings for #depmap e.g. umap on the mRNA expression data in r2platform.com

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Latest version of #depmap added to r2platform.com

R2: academic open online nocode data science platform for biomedical research

#DataScientist #biologist #clinician #genomics #Cancer

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R2 is designed to be used by #biomedical #researchers and does not require #coding or #bioinformatics expertise ( #nocode ).

Visit r2.amc.nl to explore the #DepMap data or one of the more than 2,600 other public resources that are served.

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Explore the latest #DepMap resource in a data-driven UMAP embedding in the R2 open online #genomics #data #science platform ( r2.amc.nl )

The R2 'sample maps' section contains embeddings for hundreds of different public resources, like #UMAP, t-SNE, and manuscript figure data, ready for exploration

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SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO - Nature Analysis of large-scale CRISPR screening data, combined with experiments in patient-derived tumour organoid models, identifies PELO as a potential therapeutic target in chromosomal 9p21.3-deleted canc...

(1/3) Excited to share our latest work using
@depmap.org to uncover a new synthetic lethality in two distinct patient populations!

We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO

#CancerResearch #SyntheticLethality #Genomics #DepMap

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SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO - Nature Analysis of large-scale CRISPR screening data, combined with experiments in patient-derived tumour organoid models, identifies PELO as a potential therapeutic target in chromosomal 9p21.3-deleted canc...

Exciting new synthetic lethal target emerging from #depmap data 🧪🧬

Frequent passenger mutations in genes involved in mRNA quality control lead to a dependency on PELO-HBS1L

Congratulations to the DepMap team! @vazquezf.bsky.social
#depmap #cancertarget #syntheticlethal

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Exciting new synthetic lethal target emerging from #depmap data 🧪🧬
Frequent passenger mutations in genes involved in mRNA quality control lead to a dependency on PELO
#depmap #cancertarget #syntheticlethal

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Predicted CERES #DepMap gene dependency scores on #TCGA samples, to assess gene dependency in nearly 10,000 human tumor samples

These predicted scores can readily be explored in the open access online R2 data science platform r2.amc.nl

Designed to be used by biomedical researchers ( #nocode )

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