Inhibition of #HDAC1 and #HDAC2 induces the #ProteasomalDegradation of JAK2V617F via acetylation-dependent stabilization of SIAH2, which determines primary and permanent myeloproliferative neoplasms (MPNs) survival. @mainzuniversity.bsky.social
#OpenAccess: doi.org/10.1038/s413...
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