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Epigenetics Update - HIF-activated priming of TRAIL-induced cell death determines epigenetic vulnerability in kidney cancer bit.ly/4cNlsEi

Yingfei Wang and Weibo Luo reporting in Cell Rep Med

#Epigenetics #Cancer #HIF #KidneyCancer
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Gain deeper insights into gene regulation; epigenometech.com

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#VNS
CKAP2 hugs HIF-1α, timing its rise in ischemic retina; silencing CKAP2 clips the oxygen sensor, curbing hypoxic angiogenesis. 👁️🔥
Details: www.maxapress.com/article/doi/10.48130/vns...
#oxygensensor #hif #sensor

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Here you can see a cryoEM structure of HIF-1a-ARNT dimer in complex to a synthetic DNA (PDB code: 9OFU)

Rendering by Francisco J. Enguita (@paco.enguita) made with #ProteinImager

#SciArt #molecularart #hif #promoter #dna #complex #transcription #cryoem

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🚨 Antibody of the Week 🚨Meet AbFlex® PHD2 (EGLN1) rAb

PHD2 is a cellular oxygen sensor that regulates HIF stability — a critical factor in hypoxia, cancer, and metabolic pathways.

👉 Explore and order today: bit.ly/3KfMjNm
_________
#AntibodyOfTheWeek #Hypoxia #HIF #ResearchTools #ActiveMotif

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Planefence ICAO: AE1196
Flt: RCH890 AIRMOBILITYCOMMAND HIF - BGR
First seen: 2025-07-24 15:37:24 EDT
Min Alt: 27975 ft MSL
Min Dist: 1.5 mi
planefence adsb - adsbexchange - link

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Available online - the Review "The HIF axes in cancer: #angiogenesis, metabolism, and immune-modulation" from Karen Acuña-Pilarte and Mei Yee Koh.

#Hypoxia #HIF #TumorMicroenvironment #MetabolicReprogramming #Therapeutics

Read it here: authors.elsevier.com/sd/article/S...

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Ayo Simon Okosun, den ægte ASO, skifter til Hvidovre IF. Det elsker jeg ret meget #HIF #1div

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Screenshot von 

lobbypedia.de
[von LobbyControl]

Thorsten Herdan

• von 6/2014 bis 5/2022 Leiter der Abteilung II Energiepolitik Wärme und Effizienz" im BMWK

• seit 12.05.2022 CEO von HIF EMEAE; HIF Global ist das weltweit führende eFuels-Unternehmen

Screenshot von lobbypedia.de [von LobbyControl] Thorsten Herdan • von 6/2014 bis 5/2022 Leiter der Abteilung II Energiepolitik Wärme und Effizienz" im BMWK • seit 12.05.2022 CEO von HIF EMEAE; HIF Global ist das weltweit führende eFuels-Unternehmen

#HIF Global ist das weltweit führende #eFuels-Unternehmen 🥳

1 fucking Tankladung im Monat - in Chile, nicht klimatneutral hergestellt.

#Technologieoffenheit und so #FDP #CDU #EONReiche

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Thorsten #Herdan
2014 bis 01/22:
Abteilungsleiter Energiepolitik
im #BMWK gibt 8 Mio € Förderung (11/2020 unter #Altmaier #CDU) frei an #Siemens et all für #HaruOni „Power-to-Methanol“ Anlage in
#Chile, betrieben von #HIF und wechselt dann zu HIF.

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Government support for new 1,600-home neighbourhood withdrawn Funding was originally secured in 2019

ICYMI, here's why #Somerset Council has lost £14.2m of government-backed loans to deliver 1,600 new homes in #Taunton: www.somersetlive.co.... #LDReporter #Staplegrove #HIF #A358

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What's up with the Production of #EFuels in #Chile?

In 2022, #Siemens #Energy, #Porsche, and #HIF inaugurated a pilot plant for the production of #EMethanol and #EGasoline in southern Chile. The #HaruOni plant was intended to be just the beginning — 1/2

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Original post on nrw.social

What's up with the Production of #EFuels in #Chile?

In 2022, #Siemens #Energy, #Porsche, and #HIF inaugurated a pilot plant for the production of #EMethanol and #EGasoline in southern Chile. The #HaruOni plant was intended to be just the beginning — with plans for large-scale production just a […]

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Government support for new 1,600-home neighbourhood withdrawn Funding was originally secured in 2019

More than 1,600 new homes in #Taunton will now be built without any government support after a £14.2m loan from Homes England was withdrawn: www.somersetlive.co.... #LDReporter
#Somerset #HIF #A358 #Staplegrove

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Diabetes-Associated Blindness Is Due To Low Blood Sugar. Johns Hopkins preclinical studies demonstrate how hypoglycemia triggers retinal damage. #diabetes #hypoglycemia #hif #diabeticretinopathy #32134D

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La #RevistaSEBBM de @sebbm.bsky.social incluye un resumen de nuestro último artículo en #RedoxBiology en el que relacionamos #NCLX #mitocondria con la respuesta a #hipoxia por #HIF

@elisanavarro.bsky.social

👇

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"Hasse Holmquist - Ein Mann lebt seinen Traum"

(Aus: Fuma Februar 1986)

#holmquist #f95 #hif #bscyb #nff #botd #happybirthday

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Hypoxia Inducible Factor 1α-driven steroidogenesis impacts systemic hematopoiesis Glucocorticoids regulate hematopoiesis, but how chronic elevation of endogenous glucocorticoid production affects hematopoietic stem cell (HSC) function and immune cell development remains incompletel...

Our latest preprint shows what prolonged glucocorticoid exposure can do to the immune system: HIF1⬇️🐁->GC⬆️(+Receptor)-HSPC->Immune❄️☀️ www.biorxiv.org/content/10.1... CRC-TRR 205 @adrenal-research.bsky.social ! #hypoxia #glucocorticoids #HIF #HSC #Immunology

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🩸 Kidney Oxygen Sensing 🏥
The kidneys regulate EPO based on oxygen levels. In #CKD, impaired sensing leads to anemia. 🏗️ Proximal tubule hypoxia plays a key role, while #HIF and #SGLT2i therapies may restore EPO production. #RenalPhysiology #Anemia

academic.oup.com/ndt/article/...

@theisn.org

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Chilean HIF moves forward on 1 GW solar power plant in Uruguay Highly Innovative Fuels Global (HIF Global) has reached a milestone on its proposed US$6bn hydrogen-based e-fuel plant in Paysandú, in Uruguay, as it has obtained approval for the recategorization of…

Chilean #HIF moves forward on 1 GW #solar power plant in #Uruguay #energysky

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Fodboldtrøjefredag ⚽️❤️

I dag er det Fodboldtrøjefredag! Jeg støtter op om Børnecancerfonden ved at tage min fodboldtrøje på – en lille gestus med et stort budskab. Sammen kan vi gøre en forskel for børn ramt af kræft.

Hvilken trøje har du på i dag? #FodboldtrøjeFredag #Børnecancerfonden #HIF

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Hellsinki Industrial Festival 2025 Spring Edition coming up next week already! 14.03.2025 Friday. Got your tix yet?

#industrial #ebm #goth #gothgoth #hellsinkiindustrialfestival #hif #ääniwalli

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🧐How does your kidney sense oxygen?
The #HIF pathway holds the key! 🏥🔬

From hypoxia to gene expression, this intricate system regulates metabolism, angiogenesis & survival

🔗 doi.org/10.1093/ndt/... 🆕

@hjanders.bsky.social @NDT

#Nephrology #Hypoxia #MedSky #Physiology

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Warum das Hochalpine Institut Ftan ? 1/10
Hervorragende #Bildung in einer herausragenden #Natur. Die Wahl der richtigen #Schule für die Bildung ihres Kindes ist eine der bedeutendsten Entscheidungen, die Eltern treffen können. #HIF - erstklassige Bildung seit 231 Jahren

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Import insights in #adrenal #steroidogenesis related to #HIF #signaling

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HIF1α controls steroidogenesis under acute hypoxic stress

Very pleased to share our new manuscript rdcu.be/d9OBF. Many thanks to our collaborators for their excellent support @adrenal-research.bsky.social ! #hypoxia #steroidogenesis #HIF #miRNA

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Schweizer Meister im Orientierungslauf - herzlichen Glückwunsch Andri Aebi

Schweizer Meister im Orientierungslauf - herzlichen Glückwunsch Andri Aebi

Schweizer Meister Andri Aebi Orientierungslauf Langlauf 3.7 km

Schweizer Meister Andri Aebi Orientierungslauf Langlauf 3.7 km

Schweizer Meister Andri Aebi Orientierungslauf Langlauf 5.9 km

Schweizer Meister Andri Aebi Orientierungslauf Langlauf 5.9 km

Schweizer Meister - herzlichen Glückwunsch Andri Aebi! Im Dez liess er schon seine Klasse aufblitzen & nun hat er gleich 2 Schweizer Meistertitel eingefahren! Richtig stark💪 Wir wünschen ihm auch für den Rest der Saison so einen tollen Lauf #Orientierungslauf #Swissski #HIF #Ftan #EducationinMotion

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Welcome Ignite: Switzerland Snow Term students - we love to have you here ☀️🏔️

#hif #eim #welcome #winterwonderland #studentlife #boardinglife #mountainexperience #switzerland

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#HIF inhibitors are a step forward for CKD patients, but further research is needed:
• Long-term safety in PD populations.
• Comparative effectiveness against ESAs.
• Real-world implementation strategies. #FutureOfAnemiaCare

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#️⃣: 93
🏟️: Tele2 Arena
👕: Hammarby IF & Djurgårdens IF
🥇: 04-06-2017 Hammarby IF - Djurgårdens IF 3-1

#HIF #DIF #Hammarby #Bajen #Djurgardens #Stockholm #Tele2Arena #Sportpark #Stadion #groundhopping #grounds

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Europe PMCEurope PMC Europe PMC is an archive of life sciences journal literature.

Update on HIF-activating drugs for the treatment of anemia in chronic kidney disease #anemia #erythropoietin #kidney #dialysis #hypoxia #HIF #nephrology europepmc.org/article/med/...

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