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A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma - Nature Cancer Zhao et al. used single-cell and spatial multiomics data analysis of human and mouse lung adenocarcinoma tumors and cell lines to reveal TP53 mutation-associated changes in cancer cells and their micr...

🚨Don't miss this Resource published now at Nature Cancer, as part of the #HTAN initiative!

'A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma'

✏️By Alexander Tsankov and colleagues

🔗 www.nature.com/articles/s43...

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Community-Notebooks/HTAN/Python Notebooks/Cross_Modality_Metadata_Matching_in_HTAN_Datasets.ipynb at master · isb-cgc/Community-Notebooks Contribute to isb-cgc/Community-Notebooks development by creating an account on GitHub.

New HTAN data is now available on ISB-CGC!
Explore the latest updates and check out our new Python notebook, which demonstrates how to merge metadata across modalities in HTAN using Google BigQuery.

#HTAN #BioData #BigQuery #ISBCGC

github.com/isb-cgc/Comm...

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This work was led by the very talented @ohsunews.bsky.social Ph.D. student Raphael Kirchgaessner with contributions from others not on social media. This work is also part of the NCI #HTAN 2/

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Featured today by @MSKLibrary: Sharing data from the Human Tumor Atlas Network through standards, infrastructure and community engagement dx.doi.org/10.1038/s415...

#HTAN #CancerData #OpenScience #DataSharing
#Bioinformatics #CancerResearch

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A new Perspective outlines the datasets, data standards, infrastructure, governance and community engagement approaches of the Human Tumor Atlas Network. #HTAN

www.nature.com/articles/s41...

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Dark times at NIH, but today's first steering committee for Phase 2 of #HTAN reminds us what's at stake. Brilliant cell atlas teams forging ahead, mapping cancer in unprecedented detail. New working groups in viz, compute & translation and outreach will be beacons of light.

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a black background with gold lettering that says " thank you " Alt: a black background with gold lettering that says " thank you "

Thanks @natureportfolio.bsky.social & #HTAN for an interesting webinar about human tumor atlases!

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a woman holding a necklace with the words " lots of questions " on the bottom Alt: a woman holding a necklace with the words " lots of questions " on the bottom

Leaders of the Human Tumor Atlas Network are answering questions from the audience related to #HTAN research and resources. www.cancer.gov/about-nci/or... @natureportfolio.bsky.social

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NCI Human Tumor Atlas Network

He is also describing HTAN Data Jamborees that bring scientists together to build unique solutions that solve relevant problems in #CancerResearch using #HTAN data and tools. data.humantumoratlas.org/jamboree

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NCI Human Tumor Atlas Network

Dr. Ken Lau is sharing that Human Tumor Atlas Network data and resources are available to the community in the #HTAN Data Portal. data.humantumoratlas.org

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The Human Tumor Atlas Network (HTAN): exploring tumor evolution in time and space Studying the evolution of cancer malignancy in space and time provides clues that are crucial for understanding how tumors develop, how they evade the immune ...

The importance of #HTAN work in advancing the understanding of cancer evolution and the macro-environment of tumors is being described by Drs. Li Ding and Ken Lau.
www.nature.com/collections/...

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Drs. Li Ding and Ken Lau are discussing unmet needs in #CancerResearch that are being addressed by #HTAN.

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a map with a red pin pointing to a location ALT: a map with a red pin pointing to a location

Dr. Li Ding is discussing how we can think about tumor atlases like Google Maps that allow us to explore the landscape of cancer at the cellular and tissue level. #HTAN

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Human Tumor Atlas Network (HTAN) The Human Tumor Atlas Network (HTAN) is constructing 3-dimensional atlases of the cellular, morphological, molecular, and spatial features of human cancers (and their surrounding microenvironments) ov...

Dr. Shannon Hughes, Deputy Director of the NCI Division of Cancer Biology is describing #HTAN, which is constructing 3D atlases of the cellular, morphological, molecular, and spatial features of human cancers (and their surrounding microenvironments) over time. www.cancer.gov/about-nci/or...

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The Human Tumor Atlas Network (HTAN): exploring tumor evolution in time and space Studying the evolution of cancer malignancy in space and time provides clues that are crucial for understanding how tumors develop, how they evade the immune ...

The Chief Editor of Nature Cancer is kicking off the Human Tumor Atlas Network (HTAN) exploring tumor evolution in time and space webinar. www.nature.com/collections/... #HTAN @natureportfolio.bsky.social

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🚨Don't miss The #HTAN live webinar later today!

🔗 workcast.com/register?cpa...

With HTAN leaders: Li Ding, Ken Lau, Shannon Hughes and Michael Snyder
Chaired by: Alexia-Ileana Zaromytidou (Chief Editor, Nature Cancer)
Produced by: Nature/Nature Portfolio

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🔬✨ Exciting advancements in #cancerresearch ! @theNCI -funded research from the Human Tumor Atlas Network (#HTAN) is providing new insights into tumor biology, including development, spread, and treatment responses.

Learn more:...

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ISB-CGC BigQuery Table Search Browse BigQuery tables of metadata and molecular cancer data from the Genomic Data Commons and other sources. Jump directly to a table to perform discovery and computation via SQL

#HTAN release 6 data is now live in #BigQuery! Check out the new tables using our BigQuery Table Search tool at bit.ly/BQTableSearch and filter Program by HTAN
#CancerMoonshot

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HTAN Notebooks — ISB Cancer Gateway in the Cloud 2.0.0 documentation

A new NCI HTAN notebook demonstrates how to create a Cancer Data Services (CDS) data import manifest using Google #BigQuery. Check out this notebook and more at bit.ly/HTAN_notebooks
#CancerMoonshot #CancerResearch #HTAN

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HTAN Notebooks — ISB Cancer Gateway in the Cloud 2.0.0 documentation

Check out the new NCI HTAN notebook, Analyzing HTAN #scRNASeq Data Using CellTypist! This notebook shows users how #HTAN single cell data can be annotated with #CellTypist. Find out more at bit.ly/HTAN_notebooks
@NCICancerBio #CancerMoonshot #CancerResearch #singlecell #RNAseq

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ISB-CGC|BigQuery Table Searcher BigQuery Table Search

#HTAN release 5 data is now live in #BigQuery! New tables include cell spatial imaging data and updated clinical and file metadata. Check out the new tables using our BigQuery Table Search tool at bit.ly/BQTableSearch and filter Program by HTAN #CancerMoonshot

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A new NCI HTAN notebook was added to our Community Notebooks! It illustrates how to use the #HTAN clinical and biospecimen #BigQuery tables to identify precancer cases and specimens. Find the notebook at bit.ly/HTAN_notebooks
#CancerMoonshot #CancerResearch

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Graph of the Spatial distribution of tumor cells in an Invasive Melanoma region

Graph of the Spatial distribution of tumor cells in an Invasive Melanoma region

A new notebook was added to our Community Notebooks in collaboration with NCI HTAN! The notebook demonstrates how to use #BigQuery Geospatial Analytics to analyze #HTAN spatial data. Check the notebook out at bit.ly/HTAN_notebooks
@NCICancerBio
#CancerMoonshot #CancerResearch

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