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Release ProteinDJ v2.0.0 - Major Update · PapenfussLab/proteindj This update introduces support for BindCraft and HyperMPNN to the ProteinDJ pipeline, template-guided structure prediction with Boltz-2, and improves container definitions for better compatibility....

Other features for v2 include template-guidance for #Boltz-2 prediction, auto-contig generation for #RFdiffusion, and models for #HyperMPNN. We have also made bug fixes, improvements to documentation, container updates and more. Details here: github.com/PapenfussLab/proteindj/releases/tag/v2.0.0

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HyperMPNN ‒ A general strategy to design thermostable proteins learned from hyperthermophiles Stability is a key factor to enable the use of recombinant proteins in therapeutic or biotechnological applications. Deep learning protein design approaches like ProteinMPNN have shown strong performa...

#HyperMPNN - A general strategy to #design thermostable #proteins learned from hyperthermophiles.

Cool stuff! Use this approach to make your favourite protein into #thermostable version!

biorxiv.org/cgi/content/...

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