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RNA-seq at different stages of human pancreatic β cell differentiation reveals proliferation dynamics and SMAD9 in directing β cell fate - Cell Death & Disease Cell Death & Disease - RNA-seq at different stages of human pancreatic β cell differentiation reveals proliferation dynamics and SMAD9 in directing β cell fate

Happy to share our paper led by Euodia Lim on identifying new genes involved in human pancreatic beta cell differentiation, now online in Cell Death & Disease! www.nature.com/articles/s41...

#atlab #stemcells #diabetes #research #IMCB #ASTAR #NUS

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恭祝大家马到成功!

#atlab #stemcells #diabetes #research #imcb #astar #nus

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STARD10 regulates human pancreatic β cell differentiation and triglyceride metabolism Teo and colleagues uncovered the role of T2D-associated STARD10 lipid transfer protein in human beta cells. They found STARD10 to be important for proliferation and INS+ beta cell formation. Loss of S...

Happy to share our latest work led by Wei Xuan & Shabrina, in close collaboration with Prof Guy Rutter. Studying the role of T2D associated gene Stard10 in human beta cells for Precision Medicine!

#atlab #stemcells #diabetes #research #imcb #astar #nus

www.cell.com/stem-cell-re...

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Sincere thanks Jingmei for this nice gift (stem cell; beta cell) for me and the AT Lab! Jingmei and I had a very fun, fruitful and meaningful partnership as Director of Graduate Affairs, supporting BMRC Astar scholars.

#atlab #stemcells #diabetes #research #imcb #astar #nus

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Congratulations to our 9th PhD graduate, Dewei Kong from AT Lab! We are all very proud of your development in the past 4 years. All the best for your next exciting journey!

#atlab #stemcells #diabetes #research #imcb #astar #nus

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Models of hyperglycaemia in diabetes mellitus and its complications - Nature Reviews Endocrinology Many different models are used in research into diabetes mellitus, and each has strengths and limitations. In this Review, the authors explain several in vivo and in vitro models of hyperglycaemia and...

Our lab specialises on Stem Cells, Beta Cells and Diabetes. Naturally, we think a lot about glucose and what hyperglycaemia means. Have a read on our latest review in Nat Rev Endo to find out more!

#atlab #stemcells #diabetes #research #imcb #astar #nus

www.nature.com/articles/s41...

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AT Lab Year-End Gathering and Appreciation 2025. Team bonding at Superpark, BBQ and post dinner drinks. Thankful for everyone’s hardwork in 2025, and certainly getting recharged for 2026 to come!

#atlab #stemcells #diabetes #research #imcb #astar #nus

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Back for the Third Time: Organoid Day 2026! Organoid Day returns with expert talks and the latest research in 3D cell culture. Sign up now—spaces are limited!

Together with Stem Cell Tech and NUS Precision Medicine Translational Research Programme, we at IMCB are co-hosting the 3rd Organoid Day on 12 Feb 2026. Highly relevant for NAMs. Come sign up and join us!

#stemcells #organoids #nams #imcb #astar #nus

www.stemcell.com/forms/organo...

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An absolute delight to have been invited to Taiwan Society for Stem Cell Research (TSSCR) to give a talk. Lots of excellent science, meeting Prof Teh from SG, many other colleagues and making new connections with Taiwan! More photos to follow.

#atlab #stemcells #diabetes #research #imcb #astar #nus

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Some of the AT Lab folks attending our Annual Stem Cell Society Symposium 2025. Learning more about stem cells and cell therapy!

#atlab #stemcells #diabetes #research #celltherapy #imcb #astar #nus

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Happy to meet old friends and make new ones. Thank you Kenichiro Kamei and Jeremy Teo for the kind invite to NYUAD in Abu Dhabi for a Living Therapeutics talk!

#atlab #stemcells #diabetes #celltherapy #imcb #astar #nus

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Thankful for the invite and warm hospitality. Had a good time meeting new friends and colleagues from Malaysia, working in academia and research, on cardiovascular and metabolic disease.

#atlab #stemcells #diabetes #research #imcb #astar #nus

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Year 2 Ph.D. students Aloysius and Ryan clinched some awards at the IMCB Ph.D. Symposium. Yeah!

#atlab #stemcells #diabetes #research #CMTDivision #imcb #astar #nus

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iPSCs: Progress, Opportunities, and Challenges | Keystone Symposia Join us at the Keystone Symposia on iPSCs: Progress, Opportunities, and Challenges, January 2026, in Kyoto, with field leaders!

At IMCB CMT Division, with A*STAR BMRC CGT Flagship, & SCSS, we partner with friends at CiRA, JSRM, to level up hiPSCs and their utility for organoids & therapeutics. Join them in Kyoto!
#imcb #astar #nus #scss #aascrm #CiRA #jsrm #stemcells #celltherapy

www.keystonesymposia.org/conferences/...

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It was our pleasure at Stem Cell Society Singapore (SCSS) to have esteemed Mahendra Rao visit us, share his wisdom on stem cells, cell therapy, and how to cross over from excellent science to industry and therapeutic strategies!

#stemcells #celltherapy #scss #imcb #astar #nus

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The Cell and Molecular Therapy (CMT) Division at IMCB was privileged to support our Singapore MediaCorp with the filming of their drama. They were very kind to send us mooncakes. Exciting ⭐ struck experience that we’ll share later!

#CMTDivision #stemcells #celltherapy #imcb #astar #scss

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Some of us at the Cell and Molecular Therapy (CMT) Division in IMCB had a very nice exchange and engagement with colleagues from the Health Sciences Authority (HSA), Singapore. Thank you for having us!

#CMTDivision #celltherapy #cgt #imcb #astar #singapore

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Thank you L&OD/IMCB/A*STAR for the opportunity to attend the LDP at CCL. Had a great time meeting others, seeing their leadership perspectives and certainly deep introspection on self for Curiosity (mind), Compassion (heart) and Courage (act).

#leadership #imcb #astar

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Having a wonderful time at KSSCR, giving a talk on beta cells and insulin, and networking with JiHwan Song, Joseph Wu and Dongho Choi.

#atlab #stemcells #diabetes #research #imcb #astar #nus #scss #ksscr

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Done with 2 talks, sharing on Stem Cell Therapies for Diabetes and our research efforts. Next week on invited talk at the Korean Society for Stem Cell Research (KSSCR) Annual Meeting. Looking forward to expand networks in Asia!
#atlab #stemcells #diabetes #celltherapy #imcb #astar #nus #scss #aascrm

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Our pleasure to welcome Dr Taan from Siriraj Hospital, Mahidol Uni to SG. Had a lovely chat and engagement with all from AT Lab! Working towards deciphering the genetics of diabetes & impact on beta cell biology together.
#atlab #stemcells #diabetes #research #imcb #astar #nus

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AT Lab Annual Mid-Year Sports Day! A half-time recharge - setting goals, smashing them and repeat. Grateful for everyone’s continued hardwork, team building and setting a strong culture together.

#atlab #CMTDivision #imcb #astar #nus #stemcells #diabetes #research

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Stem cell therapies for diabetes - Nature Medicine Advances in beta cell differentiation have propelled cell therapies for diabetes into the clinic; this Review outlines the lessons learned from early-phase trials and discusses the clinical, manufactu...

Many are following the exciting trials in USA & China, in which human stem cell-derived islets are successfully used to treat diabetes patients & render them insulin independent for > a year. Read our review to learn more! www.nature.com/articles/s41...
#atlab #imcb #astar #nus #diabetes #research

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AASCRM Webinar 10 Jun 25 Date:   10 June 2025 (Tue) Time:   11am  -  12:30 pm (SGT) Format: Virtual (Zoom Meeting) Host:  Jonathan Yuin Han Loh, Institute of Molecular & Cell Biology, Singapore

Do sign up and join us at our monthly Asian Alliance for Stem Cell and Regenerative Medicine (AASCRM) Webinar.

Another dose of T cell therapy for you!

#stemcells #celltherapy #research #aascrm #scss #imcb #astar #nus

www.stemcell.org.sg/aascrm10jun2...

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Welcome! You are invited to join a meeting: AASCRM Webinar Series - 13 May 25 (Haoyi Wang & Hyungseok Seo). After registering, you will receive a confirmation email about joining the meeting. Welcome! You are invited to join a meeting: AASCRM Webinar Series - 13 May 25 (Haoyi Wang & Hyungseok Seo). After registering, you will receive a confirmation email about joining the meeting.

Do join us for our monthly AASCRM webinar! Next one on 13 May, Tue, 11-1230 SGT. Come join us and learn more about T cells!

#aascrm #scss #imcb #astar #nus #CMTDivision #research

stemcell.us15.list-manage.com/track/click?...

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Happy to share an important review by PhD students Dewei and Oliwia on the Genetics and Epigenetics in Gestational Diabetes contributing to Type 2 Diabetes, published in Trends Endo Metab!

#atlab #stemcells #diabetes #research #imcb #astar #nus
authors.elsevier.com/a/1k%7ESZ3jD...

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FDA Announces Plan to Phase Out Animal Testing Requirement for Monoclonal Antibodies and Other Drugs FDA Plans to Phase Out Animal Testing Requirement

Time for a greater push for Organoid work in Singapore?

#CMTDivision #imcb #astar #nus #atlab #stemcells #organoids

www.fda.gov/news-events/...).

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AT Lab at IMCB 40th Anniversary celebrations and Retreat!

#atlab #stemcells #diabetes #research #imcb #astar #nus

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Looking forward to Organoid Day 2025 this coming Thursday, 20 Mar, at NTU@OneNorth!

#stemcells #diabetes #organoids #research #imcb #astar #nus

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