#INSTIs

HIV i-Base

@hiv-i-base.bsky.social

8 months ago

Colourful i-Base graphic. The main text reads: INSTI-based ART. Risk factor for metabolic syndrome? At the top is i-Base’s website address: I hyphen base dot info. At the bottom it says, subscribe by email. A smaller, tilted square graphic on the right, reads: HTB news. 2025. HIV treatment, prevention, access, and more. The colours used in the image are two shades of light green, dark purple, magenta, teal, light blue, lilac, orange mustard, dark blue, red, and white.

Is starting ART with #bictegravir or #dolutegravir a risk factor for developing #MetabolicSyndrome?

The #MITCLAN trial published in AIDS journal shows it could be:

i-base.info/htb/51254

#HIVsky #ResearchSky #ARVs #IntegraseInhibitors #INSTIs

HIV i-Base

@hiv-i-base.bsky.social

9 months ago

Colourful i-Base graphic. The main text reads: CDC update PEP guidelines. Second-generation INSTIs will make PEP easier to take. At the top is a URL: I hyphen base dot info. At the bottom it says, subscribe by email. A smaller, tilted square graphic on the right, reads: HTB news. 2025. HIV treatment, prevention, access, and more. The colours used in the image are dark pink-red, dark pink, mustard, dark teal, light blue, dark purple, mustard, mint green, teal, orange, dark blue, red, and white.

First US #CDC #PEP #guidelines update in 9 years: our comments and breakdown of the changes:

i-base.info/htb/51025

- Switch to second-generation #INSTIs.
- Missed option to start with a double dose.
- Lack of clarification about zero-risk situations.

#HIVprevention #UequalsU #SaveHIVFunding

HIV i-Base

@hiv-i-base.bsky.social

9 months ago

Colourful i-Base graphic. The main text reads: Overcoming drug resistance to INSTIs. Five people successfully switch from CAB/RPV-LA to B/F/TAF. At the top is a URL: I hyphen base dot info. At the bottom it says, subscribe by email. A smaller, tilted square graphic on the right, reads: HTB news. 2025. HIV treatment, prevention, access, and more. The colours used in the image are two shades of dark orangey brown, dark magenta, dark green, dark blue, mustard, mint green, teal, orange, red, and white.

Is switching to second-generation #INSTIs possible after INSTI-based #DrugResistance?

5 cases of viral load resuppression on B/F/TAF despite resistance to CAB/RPV-LA reported in @aidsjournal.bsky.social:

i-base.info/htb/50867

#HIV #HIVtreatment #HIVresearch #Antiretrovirals #HIVsky #ResearchSky