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The International Society for the Study of the Lumbar Spine #ISSLS is pleased to announce that the European Spine Journal #ESJ is now the official journal of ISSLS!

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Abstracts - ISSLS/SASS Annual Meeting 2026

📣 One week left to submit your abstract ‼️

The abstract deadline for the combined #ISSLS & #SASS 2026 Annual Meeting in Cape Town, South Africa (May 11–15, 2026) has been extended until November 15, 2025 ‼️

issls2026.org/abstracts/

#ISSLS2026 #CapeTown #SpineResearch

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🌟 Welcome Dr. Tamara Mengis – Our Newest ISSLS Member! 🌟

We’re excited to welcome Dr. Tamara Mengis, PhD to the #ISSLS community of spine researchers and clinicians!

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The Combined Influence of Sleep Disturbance and Depression... : Spine havioral factors are considered major risk factors for poor outcomes after LSS. However, there is a need to explore the combined effects of preoperative factors such as sleep disturbance and depressio...

Preoperative #SleepDisturbances and #Depression independently and jointly predict higher disability and pain 12 months after lumbar #SpineSurgery.​

The latest publication in Spine by #ISSLS member Kristin R. Archer and team: journals.lww.com/spinejournal...

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🌟 Introducing Dr. Shota Tamagawa – Our Newest ISSLS Member! 🌟

ISSLS is thrilled to welcome Shota Tamagawa, MD, PhD, Assistant Professor at Juntendo University Faculty of Medicine, Tokyo, Japan, to our #ISSLS community of spine researchers and clinicians!

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Senolytic treatment for low back pain Senolytics drugs can reduce back pain by removing senescent cells from the intervertebral discs and spinal cord.

Publication in #ScienceAdvances by #ISSLS member Prof. Lisbet Haglund: www.science.org/doi/full/10.... This study investigates the potential of two senolytic drugs in treating #LowBackPain by targeting senescent cells, which accumulate with aging and contribute to #inflammation and degeneration

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📢 Publication in FASEB J by #ISSLS member Dr. Lachlan Smith et al highlights key findings using single cell RNA seq., revealing the diversity & crucial roles of notochord-derived NP cells in the postnatal mouse disc #SpineResearch #LumbarSpine #LowBackPain #RegenerativeMedicine #Biotechnology Link 👇🏼

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Development and application of predictive clinical biomarkers for low back pain care: recommendations from the ISSLS phenotype/precision spine focus group - European Spine Journal Predictive biomarkers (or moderators of treatment) are features, or more likely feature clusters, that discriminate individuals who are more likely to experience a favourable or unfavourable effect fr...

The #ISSLS Phenotype/Precision Spine Focus Group is driving advancements in low back pain management through predictive biomarkers. Their 2024 recommendations, now published in the European Spine Journal, emphasize unified terminology, robust research designs, and overcoming development barriers 👇🏼

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Meet Clara Ruiz Fernández who joined ISSLS because of the great collaborative environment between basic researchers and clinicians. As as a postdoctoral researcher at the the Tokai University School of Medicine, Clara is a key member of the #ISSLS Social Media Committee!

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Next to be introduced is Chantal Voskamp PhD, a postdoctoral researcher at the Utrecht University (Netherlands) whose research focuses on intervertebral disc regeneration using biomolecules derived from notochordal cells. Most importantly Chantal is a member of the #ISSLS Social Media Committee!

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Terence McSweeney, MSc is a doctoral researcher at the University of Oulu and #ISSLS SoMe member. His advice for (fellow) young researchers: take a few risks and go out of your comfort zone whether that's by promoting your work, networking, learning a new skill, or tackling a new topic.

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Transient Receptor Potential Vanilloid 4 Knockdown Decreases Extracellular Matrix Synthesis via Autophagy Suppression in the Rat Intervertebral Disc We conducted in vitro and in vivo TRPV4 RNA interference study in the rat intervertebral disc cells and tissues. In vitro, TRPV4 knockdown decreased extracellular matrix synthesis, cell viability, an...

📢 New study by #ISSLS member Dr. Kakutani reveals TRPV4 knockdown impairs ECM synthesis via autophagy suppression, leading to disc degeneration in rats. Underscores autophagy's role in disc health, suggesting TRPV4 as a target for new therapies #SpineResearch onlinelibrary.wiley.com/doi/10.1002/...

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Spinal cord injury in high-risk complex adult spinal deformity surgery: review of incidence and outcomes from the Scoli-RISK-1 study - Spinal Cord Series and Cases Spinal Cord Series and Cases - Spinal cord injury in high-risk complex adult spinal deformity surgery: review of incidence and outcomes from the Scoli-RISK-1 study

🚨 Perioperative spinal cord injury in high-risk adult deformity surgery is rare but devastating. The latest study in Spinal Cord Series & Cases by #ISSLS members Fan Jiang & colleagues examines its incidence, causes, outcomes, and management strategies. 🧠🔍 Full paper: www.nature.com/articles/s41...

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Differential efficacy of two small molecule PHLPP inhibitors to promote nucleus Pulposus cell health Pharmacological inhibition of PHLPP via NSC45586 promotes nucleus pulposus cell health. NSC45586 is a potential drug candidate in treating IVD degeneration.

📢 Check out the work of #ISSLS member Svenja Illien-Junger et al. in #JORSpine on PHLPP1’s role in IVD degeneration & small molecule inhibitors. Full study 👉 onlinelibrary.wiley.com/doi/10.1002/...

#SpineResearch

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Next let's introduce Luca Ambrosio, MD

As an Orthopaedic Surgeon and PhD student at Università Campus Bio-Medico di Roma, Luca is a valued member of the #ISSLS Social Media Committee. We had the chance to learn more about his journey in #SpineResearch and #ISSLS. Here's a quick Q&A!

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Next up introducing our #ISSLS SoMe committee member Elisabetta de Rinaldis! As an undergraduate medical student at Campus Bio-Medico University of Rome, Elisabetta is a valued member of the ISSLS Social Media Committee, we had the chance to learn more about her journey in spine research and ISSLS

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This research highlights that epimuscular fat may be a relevant factor in the presentation of low back pain.

#ISSLS congratulate member Jacopo A Vitale and colleagues for their work in advancing #LumbarSpine research.

#Muscle #LowBackPain #LBP #LumbarSpine #ISSLS

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Meet Jordy Schol @jordyschol.bsky.social a research fellow at the Tokai University School of Medicine. Jordy is a valued member of the #ISSLS Social Media Committee - check out his Q & A below!

#SpineResearch #RegenerativeMedicine #BioTech

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OFFICERS AND COMMITTEES — The International Society for the Study of the Lumbar Spine

Kicking things off here with a thread highlighting the #ISSLS social media committee members who curate the research highlights, event updates, and society news here, on LinkedIn and Instagram.

More info about the society committees can be found on the website: www.issls.org/officers-and...

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