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Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection | NEJM The management of prosthetic joint infection usually consists of a combination of surgery and antimicrobial therapy. The appropriate duration of antimicrobial therapy for this indication remains un...

【Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection】@nejm.org, May, 2021

#Keyarticle DATIPO Trial

👉 RCT (🇫🇷, 28 centers), 2011–2015, N=410
👉 6-week therapy failed noninferiority vs 12 weeks (18.1% vs 9.4%)

nejm.org/doi/full/10....

#IDMedEd #IDFellow #OrthoID

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【Minocycline induced hyperpigmentation】OFID 2016

👉Study of 291 patients: 54% developed hyperpigmentation, most commonly blue-gray discoloration in lower extremities, at mean duration 1.5 years.

academic.oup.com/ofid/article...

#IDMedEd #IDFellow #OrthoID #Keyarticle #MayoIDFellowship

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