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Posts tagged #MPNST

The goal is to highlight basic, pre-clinical, and clinical research shedding light on the complex tumors (#GIST, #MPNST, #PN, #glioma, #OPG, etc!) associated with one of the the most common hereditary #cancer syndromes. Focuses: #biology, #diagnostics, #prognostic factors, #tx

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2/ In our study, we show how NF1-deficient malignant peripheral nerve sheath tumors (MPNSTs) develop adaptive resistance to MEK inhibitors by upregulating PDGFRβ transcription and increasing RAF dimer formation.

#CancerResearch #MPNST

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A drug to watch for #braincancer? Identified in 2014 by the same lab in #MPNST, the target IMPDH2 has high homology between humans and mice... ergo, the xenograft data might reflect toxicity as well as efficacy; drug may be relevant and worth clinical trials... #btsm aacrjournals.org/cancerres/ar...

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ღ At the moment, my health situation looks like this ღ

#PEGTube

#PiGGLine

#Tracheostoma

☛ The malignant peripheral nerve sheath tumor,
( #MPNST for short ) ☚

⁕⁕ More information about me and how you can help me ⁕⁕⁕

linktr.ee/Rolandhartl

🫶 Kind regards Roland 🫶

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