Latest posts tagged with #MethodMonday on Bluesky
#MethodMonday 🧪
How does #FlowCytometry work?
1. Cells pass single file through laser beams.
2. Lasers excite markers and scatter light linked to cell features.
3. Detectors measure the signals.
Together, this builds a detailed profile of each cell.
#AcademicSky @rdm.ox.ac.uk @medsci.ox.ac.uk
#MethodMonday 🧪
New month, new method: What is flow cytometry?
It is a powerful technique used for hundreds of applications, including clinical diagnostics, basic research, and discovery.
#FlowCytometry #WIMMResearch #CellAnalysis #AcademicSky #CellSorting @rdm.ox.ac.uk @medsci.ox.ac.uk #Oxford
#MethodMonday 🧪
Meet the #Imaging Facility at the #MRCWIMM
With over 15 years of expertise each, our two MRC WIMM imaging specialists maintain the instruments and support researchers working with a diverse range of research questions and imaging demands.
@medsci.ox.ac.uk @rdm.ox.ac.uk #AcademicSky
#MethodMonday 🧪:
How is #imaging used in research at the #MRCWIMM?
Scientists choose microscopes to image specimens and to measure, track, and record changes during development, disease progression, or drug treatment.
#AcademicSky @rdm.ox.ac.uk @medsci.ox.ac.uk
#MethodMonday 🧪
How does imaging work?
There are many types of light microscopes, from basic widefield and epifluorescence systems familiar from school laboratories, to advanced techniques such as laser scanning confocal, spinning disc confocal, and super resolution microscopy.
#MethodMonday 🧪
What is #imaging in biomedical research?
Imaging means a diverse set of methods to visualise and quantify biological structures, specimen and their function.
@medsci.ox.ac.uk
@rdm.ox.ac.uk
A group picture of staff and users of the Mass Cytometry facility
#MethodMonday 🧪
Behind every powerful technique is a team of dedicated scientists.
Meet the MRC WIMM Mass Cytometry Facility, where our mass cytometer helps researchers explore biology at single-cell resolution.
#WIMMResearch #MassCytometry #CoreFacilities #ScienceBehindTheScenes #MeetTheTeam
Just stumbled upon one of the later #MethodMonday posts of yours, and I have to say, it's a very interesting idea!
It's always nice to see information on research become more accessible to the public (and to the researchers & institutions who are curious about others' methodologies 😜)
#MethodMonday 🧪
What makes #MassCytometry such a powerful tool for the #MRCWIMM researchers?
#WIMMResearch #Immunology #Hematology #SingleCellScience
@medsci.ox.ac.uk @drakesmith-lab.bsky.social 🧬
#MethodMonday 🧪
So… how does #MassCytometry actually work? 🤔
1. Cells are stained with antibodies tagged to rare heavy metals
2. Each cell is vaporised and ionised in a plasma
3. Ions are separated by their mass and detected in a time-of-flight (TOF) mass spectrometer
#MethodMonday From now on, each week, we’ll highlight a different research method used at the #MRCWIMM, breaking down how it works and why it’s important. 🧪
Here we go!
Ever wondered how scientists can measure dozens of proteins on a single cell? #MassCytometry makes this possible!
The diaphragm is a flexible dome blocking sperm from the cervix, needing spermicide, and is 83% effective with typical use. It's reusable, hormone-free, requires a prescription, and comes in various sizes—consult a provider for fitting.
#MethodMonday
Abstinence is choosing not to have sex, completely preventing pregnancy. It's the only 100% effective method when done consistently.
✅ No medical side effects or cost
❌ Needs communication and planning.
It's a valid choice for any reason, temporary or long-term.
#MethodMonday
Spermicide is a chemical that kills sperm, found in gel, cream, foam, or film forms. It’s 72% effective alone but works better with condoms or a diaphragm.
✅ Over-the-counter access
❌ Use before sex. It may cause irritation and doesn’t protect against STIs.
#MethodMonday
Withdrawal involves pulling out before ejaculation to avoid pregnancy. It's about 80% effective but hard to execute flawlessly.
✅ No prescription needed
❌ Not fully reliable; sperm may be present beforehand.
Works best with another method, like condoms or spermicide.
#MethodMonday
These methods track your cycle (temperature, mucus, calendar) to avoid sex on fertile days. With perfect use, they're 95% effective, but typical use drops to 76%.
✅ Hormone-free, supports body literacy
❌ Needs daily tracking
#MethodMonday
Permanent birth control includes tubal ligation for those with ovaries and vasectomy for those with testicles, both over 99% effective. They are one-time procedures, not easily reversible, and safe, with vasectomy typically having a quicker recovery.
#MethodMonday
Emergency contraception stops pregnancy after unprotected sex or contraceptive failure. Plan B (no prescription) works best within 72 hours, while Ella (prescription) is effective for 5 days. It's NOT an abortion pill — it prevents ovulation, not implantation.
#MethodMonday
Internal condoms are worn inside the vagina to protect against pregnancy and STIs. They’re about 79% effective in typical use.
✅ Gives more control to the receptive partner
❌ Takes a little practice
Hormone-free and accessible. Use with lube for extra comfort!
#MethodMonday
The IUD is a T-shaped device inserted into the uterus for pregnancy prevention, lasting 3-12 years and over 99% effective. It provides long-term, low-maintenance protection but needs a provider for insertion and removal. There are hormonal and copper types—consult your provider.
#MethodMonday
Explaining why "woke" is a good thing to one person and an insult to another. On this #methodmonday we dive in #SymbolicInteractionism #sociology
