#NatureGenetics

MRC Weatherall Institute of Molecular Medicine

@imm.ox.ac.uk

3 months ago

Detecting and quantifying clonal selection in somatic stem cells - Nature Genetics SCIFER detects clonal selection in whole-genome sequencing data using a population genetics model. Applied to a range of somatic tissues, SCIFER quantifies stem cell dynamics and infers clonal ages an...

Featured article: Körber et al., Nature Genetics (2025) 👇 www.nature.com/articles/s41...

#StemCells #CancerResearch #SystemsBiology #MathematicalModelling #Bioinformatics #NatureGenetics #MRCWIMM

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Surrey Psychology

@surreypsychology.bsky.social

10 months ago

How Genes Influence the Timing of a Baby's First Step The science behind motor milestones and learning to walk.

🧬 👶 🐥 How do genes influence when a baby takes their first step?
Our colleague Prof Angelica Ronald explores this question in a fascinating new blog post on Psychology Today. Drawing on her team’s recent publ in #NatureHumanBehaviour and #NatureGenetics.
www.psychologytoday.com/us/blog/surr...

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International Consortium on Meningiomas (ICOM)

@icomeningioma.bsky.social

1 year ago

Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution Calixto-Hope G. Lucas, Kanish Mirchia, Kyounghee Seo, Hinda Najem, William C. Chen, Naomi Zakimi, Kyla Foster, Charlotte D. Eaton, Martha A. Cady, Abrar Choudhury, S. John Liu, Joanna J. Phillips, Stephen T. Magill, Craig M. Horbinski, David A. Solomon, Arie Perry, Harish N. Vasudevan, Amy B. Heimberger & David R. Raleigh

Read through the article “#SpatialGenomic, #biochemical & cellular mechanisms underlying #meningioma heterogeneity and evolution” in #NatureGenetics:

go.nature.com/43j3Mvy

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Danve Castroverde

@danvec.bsky.social

1 year ago

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...

Excellent paper in #NatureGenetics on the development of the ChIP-DIP assay, which generates simultaneous ChIP-Seq data for several DNA-associated proteins in a single experiment! 👀😱👏 @natureportfolio.bsky.social

www.nature.com/articles/s41...

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