Great quote
Waddington
Seen @DBT_inStem
#Embryo #CellsRUs #NotInTheGenes
Latest posts tagged with #NotInTheGenes on Bluesky
Great quote
Waddington
Seen @DBT_inStem
#Embryo #CellsRUs #NotInTheGenes
@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
Looking forward to discussing why “genetics is not that simple” tomorrow in Lisboa. Thank you Fundacao Francisco Manues do Santos and GIMM for the opportunity
ffms.pt/en/agenda/al...
#NotInTheGenes #CellsRUs #Gastrulation
In this beautiful system, we could show uncoupling of gene expression profiles, morphology and patterning… #NotInTheGenes 😉 (also includes a method to do long term 🔬 of elongating gastruloids)
Thank you to all involved @jeromewongng.bsky.social @thomasgregor.bsky.social @alexandremayran.bsky.social
Today is a special day, some would call it the first of the rest of my life.
I look forward to doing the same as before, from a different vantage point, trying to use what I have learnt to keep on learning. Thank you to all who have taught me.
#NotInTheGenes #CellsRUs
Loved it!! And would recommend to all my scientist friends.
#NotInTheGenes
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs
A lot happened in the lovely #Barcelona this week. The highlight being @amartinezarias.bsky.social star-studded symposium. Incredible impact this man has on lives and work of scientists. You can’t buy that, you have to earn it. #notinthegenes 🤠➡️🎩
YES!
#NotInTheGenes #CellsRUs
Need to put an effort to understand cells, the interpreters and users of the genes
#CellsRUs #NotInTheGenes
Hablando con @adrian_science sobre ‘el dia 14. Como las células diseñan la vida’ y sus cuitas con los #genes
shorturl.at/oZcyf
en castellano.
Mas en @EdicionesPaidos “Las arquitectas de la vida’
#NotInTheGenes #CellsRUs
Just heard @wcratcliff.bsky.social on the origin of #multicellularity www.youtube.com/watch?v=MsvD...
Great to hear that cells harnessing physics was a significant step & to have a proper discussion of the question not led by the ‘power’ of genes. Well worth a listen.
#NotInTheGenes #CellsRus
It is also of interest that it not that straightforward to map the AP heterochrony to GRNs and that we need to expand our horizons. Emergent properties of cell ensembles can govern gene activity and can do more than #GRNs #NotInTheGenes
Very important @nicolettapetridou.bsky.social report #mechanochemical signalling control fate transitions www.biorxiv.org/content/10.1... w/ wide/significant implications. Perhaps the clearest indication so far of HOW #NotInTheGenes cell interactions mechanical pattern gene expression
#MustRead
Right after the spanish edition of #TheMasterBuilder comes the Portuguese one, thanks to www.temasedebates.pt
Have a look for a cell’s eye view of Biology in contrast with the widespread gene’s eye.
#CellsRUs #NotInTheGenes
Great visit/talks from F. Corson on his work with @jeromegros.bsky.social
#Mechanobiology and #GRNs in avian #gastrulation www.nature.com/articles/s41... The output is clearly the product of an interaction between both but one has to start and rule; there is much that is #NotInTheGenes
Yes, Sui Huang has been thinking (and writing) about this for many years and is one of the most insightful biologists I know. This is, indeed, an important piece.
Maybe some things are #NotInTheGenes
Agree 💯 shorturl.at/U24tJ but there are more reasons why the promise will not be met and they have to do with the #cells that are needed to make the experiment: read about it in The Master Builder basicbooks.uk/titles/alfon...
There is much that is #NotInThegenes
These specific polarity defects are challenging to explain by direct transcriptional regulation alone.
While Stat3 transcriptional regulation likely contributes...
#NotInTheGenes
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Our findings highlight non-transcriptional functions of Stat3, propose an overlooked feature in cell polarity – the polarization competence (see below), and advance our understanding of female reproduction.
#NotInTheGenes
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Can agree that we can learn & have learnt a lot from activity of genes but a #cell isn’t a straightforward/non-linear output of their interactions. The properties that define a cell, not to mention their interactions, are #NotInTheGenes and cannot be guessed by AI.
Very good to meet @cedricboeckx.bsky.social
www.icrea.cat/community/ic...
today and to share much in common on the need to move away from #genes as an explanation for phenotypes, whether this is #development #behaviour or #language
#NotInTheGenes
Thoughtful and important discussion for all biologists here!
Although the survey was only answered by few people, the difference between what is expected by the field to be important VS what individual scientists think is important is quite striking. #NotInTheGenes 😄
January has been a plentiful month for #gastruloid #preprints. Here @thomasgregor.bsky.social @denisduboule.bsky.social & colleagues introduce a new family of #hydrogels and probe the effect of mechanical constrains on morphogenesis www.biorxiv.org/content/10.1...
#NotInTheGenes #InNumbersWeTrust
#NotInTheGenes is a way to bring attention to the realm of the cell.
Thank you. Glad to read this. In order to solve problems, to have answers, we need questions and to raise them was, is, one of the aims of the argument here. #NotInTheGenes #CellsRUs
Then we wondered, how would this impact transcription, would it reflect gastruloid's temporality or morphology? In contrast with morphology, the emergence of a Mesp2 pole was incredibly tight between different sizes #NotintheGenes?
Then we wondered, how would this impact transcription, would it reflect gastruloid's temporality or morphology? In contrast with morphology, the emergence of a Mesp2 pole was incredibly tight between different sizes #NotintheGenes?