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Posts tagged #OncoAlert

🔷 However, the combination did not improve overall survival (OS) (15.0 vs 17.9 months; HR 1.15) and was associated with higher grade 3–4 adverse events (66.9% vs 38.3%).

🔗 Read more: bit.ly/ONCOnews13-M...

#ONCOnews #OncoAlert #OncEd #Oncology #CancerResearch #Immunotherapy #TargetedTherapy

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🔷 84% of patients receiving Romiplostim avoided CIT-related chemotherapy delays or dose reductions vs 36% with placebo (OR 10.16, P<0.001).

🔗 Read more: bit.ly/ONCOnews-12M...

#ONCOnews #OncoAlert #OncEd #Chemotherapy #Thrombocytopenia #ChemotherapyInducedThrombocytopenia #Oncology #Cancer

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🔷 If cleared, the system could improve surgical accuracy and potentially reduce the need for repeat procedures. Innovations like this aim to enhance outcomes and support more effective breast-conserving surgery.

🔗 Read more: bit.ly/ONCOnews-12M...

#ONCOnews #OncoAlert #OncEd #BreastCancer #Breast

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Congratulations to Dr. Tyler Jacks of @mitkochinstitute.bsky.social on receiving the 2026 Medal of Honor from the American Cancer Society!

🔗 More here: pressroom.cancer.org/medal-of-hon...

The Medal of Honor ceremony will be held on March 14, 2026 in Washington, D.C.

#CanSky #OncoSky 🧪 #OncoAlert

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🔷 Findings highlight how advanced imaging may refine prognosis and guide more personalized treatment strategies in prostate cancer.

🔗 Read more: bit.ly/ONCOnews-11M...

#ONCOnews #OncoAlert #OncEd #ProstateCancer #PSMAPET #Oncology #CancerResearch #CancerImaging #PrecisionMedicine #Urology #Cancer

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🔷 The study explores whether this combination strategy can offer improved clinical outcomes compared with standard immunotherapy alone.

🔗 Read more: bit.ly/ONCOnews-11M...

#ONCOnews #OncoAlert #OncEd #LungCancer #NSCLC #CancerResearch #Oncology #Immunotherapy #CancerTreatment #ClinicalTrials

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🔷 This marks the first positive Phase III trial for the oral CELMoD Mezigdomide, with a safety profile consistent with prior studies.

🔗 Read more: bit.ly/ONCOnews10Ma...

#ONCOnews #OncoAlert #OncEd #MultipleMyeloma #Hematology #Oncology #CancerResearch #ClinicalTrials #Phase3Trial

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🔗 Read more: bit.ly/ONCOnews09Ma...

#ONCOnews #OncoAlert #OncEd #BreastCancer #TrastuzumabDeruxtecan #AntibodyDrugConjugate #ADC #CancerTreatment #Oncology #OncologyNews

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🔷 Approval is based on the Phase III POD1UM-303 trial, where the combination reduced the risk of progression or death by 37% and improved median PFS to 9.3 months vs 7.4 months with chemotherapy alone, with no new safety signals reported.

🔗 Read more: bit.ly/ONCOnews09Ma...

#ONCOnews #OncoAlert

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🔷 Development of Giredestrant continues across settings, including evERA in advanced disease (NDA accepted by the FDA) and lidERA in early breast cancer, with submission planned soon.

🔗 Read more: bit.ly/ONCOnews09Ma...

#ONCOnews #OncoAlert #OncEd #BreastCancer #AdvancedBreastCancer #Metastatic

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🔷 Based on the MajesTEC-3 trial, this combination brings together a BCMA-targeted bispecific antibody and CD38-directed therapy, offering a novel dual-targeted approach for patients who have received prior lines of therapy.

🔗 Read more: bit.ly/ONCOnews06-M...

#ONCOnews #OncoAlert #OncEd #Oncology

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🔷 Based on results from the phase 3 BRUIN CLL-321 trial, this treatment expands options for patients progressing after prior BTK inhibitor therapy, marking a key milestone in hematologic oncology.

🔗 Read more: bit.ly/ONCOnews04-M...

#ONCOnews #OncoAlert #OncEd #Oncology #CancerCare #Cancer

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🔷 Based on Phase 3 VERIFY data, if approved, Rusfertide could become a first-in-class therapy, offering a novel treatment approach for patients requiring improved hematocrit control.

🔗 Read more: bit.ly/ONCOnews03-M...

#ONCOnews #OncoAlert #OncEd #BiotechNews #PharmaNews #Oncology #Hematology

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New from our ACS Cancer Surveillance team:

Rates of #ColorectalCancer (CRC) are increasing in younger generations, largely by cancers in the distal colon and rectum. Rectal cancer now makes up nearly one third of all CRC diagnoses.

#CanSky #OncoSky #OncoAlert #CancerStatistics 🧪

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🔷 The LITESPARK-022 Phase 3 data suggests added benefit from combining PD-1 blockade with HIF-2α inhibition in the post-nephrectomy setting.

🔗 Read more: bit.ly/ONCOnews02-M...

#ONCOnews #OncoAlert #OncEd #Oncology #CancerResearch #Immunotherapy #TargetedTherapy #RenalCellCarcinoma #KidneyCancer

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🔷 This regulatory milestone underscores continued progress in targeted therapies for lung cancer and reinforces momentum in precision oncology.

🔗 Read more: bit.ly/ONCOnews27Fe...

#ONCOnews #OncoAlert #OncEd #Oncology #CancerCare #Healthcare #Medicine #Innovation #Science #MedicalResearch #Pharma

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🔷 The findings signal a potential new therapeutic option for patients with limited treatment choices in advanced TNBC.

🔗 Read more: bit.ly/ONCOnews27Fe...

#ONCOnews #OncoAlert #OncEd #Oncology #CancerCare #Healthcare #Medicine #Innovation #Science #Oncology #CancerResearch #HealthTech

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🔷 These findings reinforce the value of a bone-targeted combination strategy in improving outcomes for patients with advanced, high-risk disease.

🔗 Read more: bit.ly/ONCOnews27Fe...

#ONCOnews #OncoAlert #OncEd #Oncology #CancerCare #Healthcare #Medicine #Innovation #Science #MedicalResearch

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🔷 This approval bolsters biomarker-driven strategies in first-line metastatic colorectal cancer, giving clinicians a new evidence-based option to improve patient outcomes.

🔗 Read more: bit.ly/ONCOnews25Fe...

#ONCOnews #OncoAlert #OncEd #Oncology #CancerCare #ColorectalCancer #mCRC #Cancer

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🔷 Findings from the randomized, double-blind study led by GETNE provide important evidence on the role of adding targeted therapy to Somatostatin analogs in progressive NET management.

🔗 Read more: bit.ly/ONCOnews23Fe...

#ONCOnews #OncoAlert #OncEd #NeuroendocrineTumors #NETs #Oncology #Cancer

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🔷 This first all-oral, fixed-duration (14 cycles), chemo-free regimen reduced progression/death risk by 35% vs.chemoimmunotherapy in the AMPLIFY study (HR 0.65; p=0.0038)

🔗 Read more: bit.ly/ONCOnews23Fe...

#ONCOnews #OncoAlert #OncEd #FDAApproval #CLL #Leukemia #Hematology #Oncology #Cancer

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🔷 If approved, giredestrant could offer a targeted endocrine therapy option designed to overcome resistance associated with ESR1 mutations in HR-positive disease.

🔗 Read more: bit.ly/ONCOnews23Fe...

#ONCOnews #OncoAlert #OncEd #FDAApproval #BreastCancer #BreastCancerAwareness #Oncology

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🔷 Findings support chemotherapy-first strategies as a potential radiation-sparing option, helping reduce treatment burden while maintaining efficacy in selected patients.

🔗 Read more: bit.ly/ONCOnews20Fe...

#ONCOnews #OncoAlert #OncEd #RectalCancer #ColorectalCancer #Oncology #CancerResearch

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🔷 The approval expands treatment access across 33 countries, offering a new immunotherapy option for patients with limited alternatives after BCG therapy.

🔗 Read more: bit.ly/ONCOnews20Fe...

#ONCOnews #OncoAlert #OncEd #BladderCancer #Oncology #CancerTreatment #Immunotherapy #CancerResearch

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🔷 If approved, iberdomide could offer a novel treatment option for heavily pretreated patients with limited therapeutic choices.

🔗 Read more: bit.ly/ONCOnews18Fe...

#ONCOnews #OncoAlert #OncEd #MultipleMyeloma #Hematology #Oncology #CancerResearch #CancerTreatment #FDA #FDAApproval

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🔷 The study evaluated whether dual checkpoint inhibition could improve recurrence outcomes over standard PD-1 blockade; however, the combination increased immune-mediated and serious adverse events without added benefit.

🔗 Read more: bit.ly/ONCOnews16Fe...

#ONCOnews #OncoAlert #OncEd #Melanoma

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🔷 Introduces Tumor Treating Fields (TTFields) therapy, a novel, noninvasive, biophysical treatment modality.

🔗 Read more: bit.ly/ONCOnews12Fe...

#ONCOnews #OncoAlert #OncEd #FDAApproval #PancreaticCancer #TumorTreatingFields #Oncology #CancerInnovation #LocallyAdvanced #MedTech #CancerCare

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This approval supports biomarker-driven treatment selection and expands access to precision immunotherapy in advanced gynecologic cancers.

🔗 Read more: bit.ly/ONCOnews12Fe...

#ONCOnews #OncoAlert #OncEd #FDAApproval #CompanionDiagnostics #PrecisionOncology #OvarianCancer #GynecologicOncology

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🔷 The approval is based on KEYNOTE-B96, which demonstrated improvements in progression-free survival (PFS) and overall survival (OS), introducing an immunotherapy-based combination strategy in platinum-resistant disease.

🔗 Read more: bit.ly/ONCOnews11Fe...

#ONCOnews #OncoAlert #OncEd #Cancer #FDA

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🔷 The randomized study is designed to assess efficacy and safety versus placebo, with progression-free survival (PFS) as the primary endpoint.

🔗 Read more: bit.ly/ONCOnews10Fe...

#ONCOnews #OncoAlert #OncEd #Glioma #Phase3Trial #ClinicalTrials #Oncology #NeuroOncology #TargetedTherapy

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