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5/5 Authors: Gabriel Reygondeau, Yulia Egorova, Kristina Boerder, Derek P. Tittensor, Kristin Kaschner, Kathleen Kesner-Reyes, Nicolas Bailly, William W. L. Cheung.

📖 Read the full paper 'AquaX: An enhanced and revised AquaMaps framework..' in #PLOSOne: journals.plos.org/plosone/arti...

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Nontargeted metabolomics analysis of potential biomarkers for patients with chronic ischemic stroke in extremely cold rural regions: An exploratory case-control study Objective Chronic ischemic stroke (CIS) is a serious cardiovascular event, closely related to genetic and environmental factors in its occurrence and development. This study aims to reveal the potenti...

Nontargeted metabolomics analysis of potential biomarkers for patients with chronic ischemic stroke in extremely cold rural regions: An exploratory case-control study #PlosOne #MassSpec dx.plos.org/10.1371/jour...

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Original post on fediscience.org

We need a better way to fund basic #research in 🇪🇺 to stimulate innovation. so far with have #Horizon program and #ERC . Both are great but we lack a lower level of funding for testing or proof of concept (2 Years ~140k€ + postdoc) no overhead allowed (100% dedicated to research) . Selection of […]

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When Horses Smell Your Fear: The Science Behind Spooked Saddles | PEP UNLIMITED LLC A new study published in PLOS One suggests that horses can detect human fear through smell, and that this may directly affect how cautious, jumpy, or stressed they become around us.

When Horses Smell Your Fear: The Science Behind Spooked Saddles
pepunlimited.com/animals/when...

#HorseS #EquineScience #HorseTraining #Bond #Communication #Psychology #PLOSOne #EmotionalContagion #HorseRiding #Horsemanship #EquineWellness #FearAndAnimals #Behavior #Handlers #Confidence #PepRaise

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When Horses Smell Your Fear: The Science Behind Spooked Saddles | PEP UNLIMITED LLC A new study published in PLOS One suggests that horses can detect human fear through smell, and that this may directly affect how cautious, jumpy, or stressed they become around us.

When Horses Smell Your Fear: The Science Behind Spooked Saddles
pepunlimited.com/animals/when...

#Horses #Behavior #Equine #Science #Training #Bond #Communication #Psychology #PLOSOne #EmotionalContagio #HorseRiding #Horsemanship #EquineWellness #Animals #HorseHandlers #Confidence #PepUnlimited

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RAINBOW trial reveals patterns in depression and weight loss A recent study published in PLOS One explores the connection between depression and weight loss during an integrated behavioral treatment program. The research, part of the RAINBOW trial, provides val...

💡 A recent study published in @PLOSONE explores the connection between depression and weight loss during an integrated behavioral treatment program.

Read more: i2db.wustl.edu/rainbow-tria...

#WashUMedicine #WashUMed #Research #PLOSOne #Depression #Weightloss #RAINBOWTrial

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Direct measurement of free glucocorticoids in small volumes of mouse and rat serum using ultrafiltration and liquid chromatography-tandem mass spectrometry Glucocorticoids are critical steroid hormones secreted from the adrenal glands. In mice and rats, over 90% of circulating corticosterone is bound to proteins such as corticosteroid-binding globulin an...

Direct measurement of free glucocorticoids in small volumes of mouse and rat serum using ultrafiltration and liquid chromatography-tandem mass spectrometry #PlosOne journals.plos.org/plosone/arti...

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#PLoSONE Experimental evidence that penis size, height, and body shape influence assessment of male sexual attractiveness and fighting ability in humans journals.plos.org/plosbiology/...

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Por qué los caballos perciben el miedo humano y se estresan Un estudio en PLOS ONE revela que los caballos huelen el miedo humano: el sudor eleva su estrés, baja el contacto y acentúa sus sobresaltos. Hay días en los que la cuadra parece idéntica a sí misma: e...

Por qué los caballos perciben el miedo humano y se estresan #19deenero #felizlunes #Caballos #Equitacion #Ciencia #BienestarAnimal #Etologia #ComportamientoAnimal #Olfato #PsicologiaAnimal #Veterinaria #ManejoEquino #PLOSOne #INRAE #IFCE donporque.com/los-caballos...

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Whole-mount staining of primate testis

Human Marmoset Macaque
Bouin's PFA fixative
0.5~50 mm³

PT-CLEAR3D staining
BABB optical clearing

Germ cell: MAGE-A4 PIWIL4
Sertoli: Vimentin Sox9
Peritubular myoid cell & Blood Vessel: α-SMA

#PLOSONE 2025
journals.plos.org/plosone/arti...

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Targeting ceramide metabolism to restore hypoxia-induced apoptosis in p53-deficient colon cancer cells Hypoxic stress in solid tumors triggers growth arrest and apoptosis through p53 activation and stabilization. This environment inactivates p53 and drives the expansion of p53-mutant clones, which acce...

Targeting ceramide metabolism to restore hypoxia-induced apoptosis in p53-deficient colon cancer cells #PlosOne #MassSpec dx.plos.org/10.1371/jour...

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A 38-plex PCR MALDI-TOF MS-based assay to detect SNPs common in elite athletes There is great demand for a novel technique to facilitate the rapid identification of multiple single-nucleotide polymorphisms (SNPs) prevalent in elite athletes. Case-control and genome-wide associat...

A 38-plex PCR MALDI-TOF MS-based assay to detect SNPs common in elite athletes #PlosOne dx.plos.org/10.1371/jour...

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Control of quiescence and activation of human muscle stem cells by cytokines Skeletal muscle homeostasis and repair depend on the activation of tissue resident stem cells called satellite cells. To understand the early molecular basis of human satellite cell activation, epigen...

New #PLOSONE paper: Control of quiescence and activation of human muscle stem cells by cytokines. #Myoblue tinyurl.com/3asw9wcv

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¿Qué revela la ciencia sobre el placer anal en las mujeres? Placer anal femenino: amplio estudio detalla caricias externas, entrada superficial y combinaciones con pautas de seguridad y lenguaje claro. La evidencia más amplia y precisa publicada hasta la fecha...

¿Qué revela la ciencia sobre el placer anal en las mujeres?
#PlacerAnal #SaludSexual #PLOSONE #Sexualidad #Lubricantes #Preservativo #OMS #NHS #España #Periodismo #DonPorque #3dediciembre #felizmiercoles
donporque.com/placer-anal-...

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TSLPR deficiency attenuates AHR independently of eosinophilia and mucus secretion in a chronic HDM mouse model of allergic asthma Background Asthma is marked by chronic airway inflammation, immune dysregulation, and airway remodeling. While TSLP is known to influence allergic diseases like asthma, the role of TSLPR in airway rem...

Our new #PLOSONE study is out! 📢
Deleting TSLPR in chronic HDM asthma lowered AHR and cut IL-4/IL-13 + HDM-IgE but eosinophils, mucus, and collagen didn’t budge 🤷‍♂️.

#Asthma biology stays complicated.

journals.plos.org/plosone/arti...

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Development and validation of ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method to quantify monotropein in blueberries Blueberries (Vaccinium species) are an economically important fruit crop rich in bioactive compounds like polyphenols and flavonoids. Interestingly, some blueberry cultivars also produce monotropein, ...

Development and validation of ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method to quantify monotropein in blueberries #PlosOne dx.plos.org/10.1371/jour...

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Mass spectrometry-based metabolomics uncovers distinct metabolic signatures and potential therapeutic targets in Plasmodium knowlesi Malaria remains a major global health challenge, caused by several Plasmodium species and transmitted via mosquito vectors. Among these, Plasmodium knowlesi is notable for its zoonotic nature, capable...

Mass spectrometry-based metabolomics uncovers distinct metabolic signatures and potential therapeutic targets in Plasmodium knowlesi #PlosOne dx.plos.org/10.1371/jour...

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A Fragmentation behavior-guided UHPLC-Q-Orbitrap HRMS method for the quantitative analysis of 26 perfluoroalkyl substances and their alternatives in water Perfluoroalkyl substances (PFASs), including newly introduced alternatives, are of global concern due to their environmental persistence, bioaccumulation, and potential health risks. We developed and ...

A Fragmentation behavior-guided UHPLC-Q-Orbitrap HRMS method for the quantitative analysis of 26 perfluoroalkyl substances and their alternatives in water #PlosOne dx.plos.org/10.1371/jour...

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Metabolomics and databases driven approach of identification of phytochemicals from seed of Salvia schimperi using high-performance liquid chromatography tandem mass spectrometry Salvia schimperi is widely used in Ethiopian folk medicine, particularly its raw and roasted seeds for treating ailments such as diarrhea. While numerous reports on its traditional uses and biological...

Metabolomics and databases driven approach of identification of phytochemicals from seed of Salvia schimperi using high-performance liquid chromatography tandem mass spectrometry #PlosOne dx.plos.org/10.1371/jour...

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Combined metabolomics and proteomics analysis of vascular cognitive impairment in hypertensive rats induced by endothelial injury Aim Based on metabolomics and proteomics research, we investigate the molecular biological mechanisms underlying vascular cognitive impairment (VCI) in rats induced by hypertension combined with endot...

Combined metabolomics and proteomics analysis of vascular cognitive impairment in hypertensive rats induced by endothelial injury #PlosOne #MassSpec journals.plos.org/plosone/arti...

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Removal efficiency of pharmaceuticals during the wastewater treatment process: Emission and environmental risk assessment The release of pharmaceuticals into the environment is a major concern. These compounds enter waterways through the effluent of wastewater treatment plants (WWTPs). However, most WWTPs using mechanica...

Removal efficiency of pharmaceuticals during the wastewater treatment process: Emission and environmental risk assessment #PlosOne #MassSpec journals.plos.org/plosone/arti...

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Comparison of mass spectrometry and fourier transform infrared spectroscopy of plasma samples in identification of patients with fracture-related infections Objectives Fracture-related infections (FRIs) have significant impact on patient outcomes. Diagnosing FRIs is challenging due to lack of robust, minimally invasive diagnostic tests in the early stages...

Comparison of mass spectrometry and fourier transform infrared spectroscopy of plasma samples in identification of patients with fracture-related infections #PlosOne journals.plos.org/plosone/arti...

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Acute radiation exposure in mice reveals traces of oxidation-mediated modifications in serum albumin High doses of ionizing radiation induce specific oxidation-mediated modifications on the sequence of amino acid that constitutes serum albumin, but the time-dependent response thereafter is unclear. W...

Acute radiation exposure in mice reveals traces of oxidation-mediated modifications in serum albumin #PlosOne #MassSpec journals.plos.org/plosone/arti...

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Preliminary study on metabolite differences between two obesity syndromes based on Q Exactive liquid chromatography–tandem mass spectrometry metabolomics Background According to traditional Chinese medicine, based on the pathogenesis, clinical manifestation, and treatment, obesity can be classified into two broad types, namely, “shi obesity” and “xu ob...

Preliminary study on metabolite differences between two obesity syndromes based on Q Exactive liquid chromatography-tandem mass spectrometry metabolomics #PlosOne journals.plos.org/plosone/arti...

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Open educational resources for distributed hands-on teaching in molecular biology. #MolecularBiology #OpenEducationalResources #PLOSone
journals.plos.org/plosone/arti...

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Puzzle Hi-C: An accurate scaffolding software. #HiC #Genomics #Bioinformatics #GenomeScaffolding #PLOSone 🧬 🖥️
journals.plos.org/plosone/arti...

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Circulating metabolites in patients with chronic heart failure are not related to gut leakage or gut dysbiosis Background The gut microbiota produces numerous metabolites that can enter the circulation and exert effects outside the gut. Several studies have reported altered gut microbiota composition and circu...

Circulating metabolites in patients with chronic heart failure are not related to gut leakage or gut dysbiosis #PlosOne #MassSpec journals.plos.org/plosone/arti...

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Making MALDI-TOF MS for entomological parameters accessible: A practical guide for in-house library creation Matrix-assisted laser desorption-ionisation time of flight mass spectrometry (MALDI-TOF MS) is a powerful analytical method that has been used extensively to identify sample ions of complex mixtures, ...

Making MALDI-TOF MS for entomological parameters accessible: A practical guide for in-house library creation #PlosOne journals.plos.org/plosone/arti...

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Nurses on the frontline during the COVID-19 pandemic in Ireland This study was conducted to examine redeployed nurses' resilience, and explore how they coped, during a period of adversity (COVID-19 pandemic). It also examines the impact on their personal and profe...

I am delighted to be chosen as a special feature for the #PLOSResearchShowcase today highlighting my recent publication. Thank you #PLOSOne

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Comparison of the composition and antiplasmodial activity of Artemisia annua teas using an untargeted metabolomic approach The use of teas made from locally cultivated Artemisia annua to fight malaria in remote areas where access to care is difficult is a matter of debate. This study aimed at document differences in the c...

Comparison of the composition and antiplasmodial activity of Artemisia annua teas using an untargeted metabolomic approach #PlosOne #MassSpec journals.plos.org/plosone/arti...

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