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Blood biochemical and gut microbiotic neural network models forecasting human biological age | Aging Aging | doi:10.18632/aging.206360. Anastasia A. Kobelyatskaya, Olga N. Tkacheva, Alexandra A. Melnitskaia, Anna K. Ilyushchenko, Lubov V. Machekhina, Irina D. Strazhesko, Alexey Moskalev

#PaperoftheDay: "Blood biochemical and gut microbiotic neural network models forecasting human biological age"

DOI ⬇️
doi.org/10.18632/aging.206360

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Healthy life extension: Geroscience’s north star | Aging Aging | doi:10.18632/aging.206359. David A. Barzilai

#PaperoftheDay: "Healthy life extension: Geroscience’s north star"

DOI ⬇️
doi.org/10.18632/aging.206359

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Characterization of tumor endothelial cells (TEC) in gastric cancer and development of a TEC-based risk signature using single-cell RNA-seq and bulk RNA-seq data | Aging Aging | doi:10.18632/aging.205928. Meng Fan, Xiaofei Xu, Yu Hu

#PaperoftheDay: "Characterization of tumor endothelial cells (TEC) in gastric cancer and development of a TEC-based risk signature using single-cell RNA-seq and bulk RNA-seq data"

DOI ⬇️
doi.org/10.18632/aging.205928

#aging #research #oa #gerontology #peerreview #publishing

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MiR-33a-5p in stored red blood cells regulates genes of innate immune response and promotes inflammation | Aging Aging | doi:10.18632/aging.205925. Jingrui Zhang, Dan Zhang, Jing Zhao, Wei Zheng

#PaperoftheDay: "MiR-33a-5p in stored red blood cells regulates genes of innate immune response and promotes inflammation"

DOI ⬇️
doi.org/10.18632/aging.205925

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice | Aging Aging | doi:10.18632/aging.206358. Naidu B. Ommi, Dwight A. L. Mattocks, Mark C. Horowitz, Sailendra N. Nichenametla

#PaperoftheDay: "D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice"

DOI ⬇️
doi.org/10.18632/aging.206358

#aging #research #openaccess #peerreview #publishing

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P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts | Aging Aging | doi:10.18632/aging.206357. Shan Zhu, Jennifer Q Zhou, Kan Wang, Ming-lei Guo, Yan Y Sanders

#PaperoftheDay: "P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts"

DOI ⬇️
doi.org/10.18632/aging.206357

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Aging retinal pigmented epithelium: omics-based insights into vision decline | Aging Aging | doi:10.18632/aging.205914. Ioan V. Matei, Luminita Paraoan

#PaperoftheDay: "Aging retinal pigmented epithelium: omics-based insights into vision decline"

DOI ⬇️
doi.org/10.18632/aging.205914

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis | Aging Aging | doi:10.18632/aging.206008. Hao Zhang, Bing Han, She Tian, Yongjun Gong, Liwen Chen, Li Liu

#PaperoftheDay: "HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis"

DOI ⬇️
doi.org/10.18632/aging.206008

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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LIMK1 promotes the development of cervical cancer by up-regulating the ROS/Src-FAK/cofilin signaling pathway | Aging Aging | doi:10.18632/aging.206007. Yajing Jia, Yongping Li, Naiyi Du, Wei Zhao, Yakun Liu

#PaperoftheDay: "LIMK1 promotes the development of cervical cancer by up-regulating the ROS/Src-FAK/cofilin signaling pathway"

DOI ⬇️
doi.org/10.18632/aging.206007

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived | Aging Aging | doi:10.18632/aging.206356. Akihiko Taguchi, Yuka Okinaka, Carsten Claussen, Sheraz Gul

#PaperoftheDay: "A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived"

DOI ⬇️
doi.org/10.18632/aging.206356

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Sevoflurane impedes neuropathic pain by maintaining endoplasmic reticulum stress and oxidative stress homeostasis through inhibiting the activation of the PLCγ/CaMKII/IP3R signaling pathway | Aging Aging | doi:10.18632/aging.206001. An Xie, Xianjie Zhang, Feng Ju, Yukai Zhou, Dan Wu, Jia Han

#PaperoftheDay: "Sevoflurane impedes neuropathic pain by maintaining endoplasmic reticulum stress and oxidative stress homeostasis through inhibiting the activation of the PLCγ/CaMKII/IP3R signaling pathway"

DOI ⬇️
doi.org/10.18632/aging.206001

#aging #research #openaccess

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Characteristics of auto-quantified tumor-infiltrating lymphocytes and the prognostic value in adenocarcinoma of the esophagogastric junction, gastric adenocarcinoma, and esophageal squamous cell carci... Aging | doi:10.18632/aging.205999. Hao Dong, Longqing Yao, Jiahui Fan, Peipei Gao, Xiaorong Yang, Ziyu Yuan, Tiejun Zhang, Ming Lu, Xingdong Chen, Chen Suo

#PaperoftheDay: "Characteristics of auto-quantified tumor-infiltrating lymphocytes and the prognostic value in adenocarcinoma of the esophagogastric junction, gastric adenocarcinoma, and esophageal squamous cell carcinoma"

DOI ⬇️
doi.org/10.18632/aging.205999

#aging #research

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Identification of <i>Escherichia coli</i> strains using MALDI-TOF MS combined with long short-term memory neural networks | Aging Aging | doi:10.18632/aging.205995. Qiqi Mao, Xie Zhang, Zeping Xu, Ya Xiao, Yufei Song, Feng Xu

#PaperoftheDay: "Identification of Escherichia coli strains using MALDI-TOF MS combined with long short-term memory neural networks"

DOI ⬇️
doi.org/10.18632/aging.205995

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Causal effects of inflammation on long-term mortality: A mendelian randomization study | Aging Aging | doi:10.18632/aging.206352. Eliano P. Navarese, Dean J. Kereiakes, Timothy D. Henry, Marc Brouwer, Giuseppe Talanas, Mehriban Isgender, Michael E. Farkouh, Jacek Kubica

#PaperoftheDay: "Causal effects of inflammation on long-term mortality: A mendelian randomization study"

DOI ⬇️
doi.org/10.18632/aging.206352

#aging #research #openaccess #openscience #peerreview #gerontology #journal #publishing #meded

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Aging-associated mitochondrial circular RNAs | Aging Aging | doi:10.18632/aging.206354. Hyejin Mun, Do-Won Ham, Nam Chul Kim, Bo-In Kwon, Young-Kook Kim, Je-Hyun Yoon

#PaperoftheDay: "Aging-associated mitochondrial circular RNAs"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #openscience #peerreview #gerontology #journal #publishing #meded

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Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV | Aging Aging | doi:10.18632/aging.206353. Alan Tomusiak, Sierra Lore, Morten Scheibye-Knudsen, Eric Verdin

#PaperoftheDay:
"Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV"

DOI ⬇️
doi.org/10.18632/aging.206353

#aging #research #openaccess #peerreview #gerontology #journal #publishing #meded

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Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer? | Aging Aging | doi:10.18632/aging.206355. Iman M. Al-Naggar, George A. Kuchel

#PaperoftheDay:
"Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?"

🔗 www.aging-us.com/article/2063...

#aging #research #openaccess #peerreview #gerontology #journal #publishing #meded

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Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancer | Aging Aging | doi:10.18632/aging.205973. Bo Tao, Ziming Wang, Dacheng Xie, Hongxue Cui, Bin Zhao, Juanjuan Li, Liang Guo

#PaperoftheDay:
"Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancer"

DOI ⬇️
doi.org/10.18632/aging.205973

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Luteolin targets the AGE-RAGE signaling to mitigate inflammation and ferroptosis in chronic atrophic gastritis | Aging Aging | doi:10.18632/aging.205969. Nailin Zhang, Pingping Chen, Xiaoyan Liang, Jianhui Sun, Qiquan Liu, Shengjiang Guan, Qiao Wang

#PaperoftheDay:
"Luteolin targets the AGE-RAGE signaling to mitigate inflammation and ferroptosis in chronic atrophic gastritis"

DOI ⬇️
doi.org/10.18632/aging.205969

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Development and validation of a nomogram to predict overall survival in patients with glioma: a population-based study | Aging Aging | doi:10.18632/aging.205967. Wei Huang, Yuhe Lei, Xiongbin Cao, Gengrui Xu, Xiaokang Wang

#PaperoftheDay:
"Development and validation of a nomogram to predict overall survival in patients with glioma: a population-based study"

DOI ⬇️
doi.org/10.18632/aging.205967

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure | Aging Aging | doi:10.18632/aging.205960. Jie Chen, Xiaohong Wei, Xuefen Wu, Qian Zhang, Guiyang Xia, Huan Xia, Hongcai Shang, Sheng Lin

#PaperoftheDay:
"Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure"

DOI ⬇️
doi.org/10.18632/aging.205960

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Needle-scalpel therapy inhibits the apoptosis of nucleus pulposus cells via the SDF-1/CXCR4 axis in a rat degenerative cervical intervertebral disc model | Aging Aging | doi:10.18632/aging.205959. Wenlong Yang, Muqing Liu, Qinran Sun, Lei Liu, Wenqing Wu, Fangming Liu, Zhizhen Liu

#PaperoftheDay:
"Needle-scalpel therapy inhibits the apoptosis of nucleus pulposus cells via the SDF-1/CXCR4 axis in a rat degenerative cervical intervertebral disc model"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #oa #gerontology #peerreview #journal #publishing

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Identification of differentially expressed genes to predict the risk of heart failure in older patients with hypertrophic cardiomyopathy | Aging Aging | doi:10.18632/aging.205956. Hao Dong, Chufan Yin, Dongping Xiao, Yong Tang

#PaperoftheDay:
"Identification of differentially expressed genes to predict the risk of heart failure in older patients with hypertrophic cardiomyopathy"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Characterization of the gut microbiota and fecal metabolome in the osteosarcoma mouse model | Aging Aging | doi:10.18632/aging.205951. Yuan Li, Xiaochen Qiao, Yi Feng, Ruhao Zhou, Kun Zhang, Yongchun Pan, Ting Yan, Lei Yan, Sen Yang, Xiaochun Wei, Pengcui Li, Chaojian Xu, Zhi Lv, Zhi Tian

#PaperoftheDay:
"Characterization of the gut microbiota and fecal metabolome in the osteosarcoma mouse model"

DOI ⬇️
doi.org/10.18632/aging.205951

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Long non-coding RNA HOTTIP promotes renal cell carcinoma progression through the regulation of the miR-506 pathway | Aging Aging | doi:10.18632/aging.205947. Chengyao Zhang, Zhiya Hu, Yongxin Fu, Jiawu Wang

#PaperoftheDay:
"Long non-coding RNA HOTTIP promotes renal cell carcinoma progression through the regulation of the miR-506 pathway"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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An immune biomarker associated with EMT serves as a predictor for prognosis and drug response in bladder cancer | Aging Aging | doi:10.18632/aging.205927. Yike Jiang, Zichuan Yu, Hao Zheng, Xuanrui Zhou, Minqin Zhou, Xitong Geng, Yanting Zhu, Shuhan Huang, Yiyang Gong, Liangyun Guo

#PaperoftheDay:
"An immune biomarker associated with EMT serves as a predictor for prognosis and drug response in bladder cancer"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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G-CSF promotes the development of hepatocellular carcinoma by activating the PI3K/AKT/mTOR pathway in TAM | Aging Aging | doi:10.18632/aging.205922. Heng Cao, Shunxiang Wang

#PaperoftheDay:
"G-CSF promotes the development of hepatocellular carcinoma by activating the PI3K/AKT/mTOR pathway in TAM"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Black phosphorus quantum dots prevent atherosclerosis in high-fat diet-fed apolipoprotein E knockout mice | Aging Aging | doi:10.18632/aging.205874. Yiran Ji, Yilin Wen, Shengwei Zhang, Bingxuan Xu, Shuai Sun, Yun Chen, Xintao Shuai, Tingting Zheng

#PaperoftheDay:
"Black phosphorus quantum dots prevent atherosclerosis in high-fat diet-fed apolipoprotein E knockout mice"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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CALCR exacerbates renal cell carcinoma progression via stabilizing CD44 | Aging Aging | doi:10.18632/aging.205586. Haiyang Yan, Zhaohui Xing, Shuai Liu, Peng Gao, Qingli Wang, Guiying Guo

#PaperoftheDay:
"CALCR exacerbates renal cell carcinoma progression via stabilizing CD44"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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Cathepsin L induces cellular senescence by upregulating CUX1 and p16<sup>INK4a</sup> | Aging Aging | doi:10.18632/aging.205955. Yuwei Wu, Danli Jiang, Qing Liu, Shaoyang Yan, Xiuzhen Liu, Ting Wu, Wei Sun, Gang Li

#PaperoftheDay:
"Cathepsin L induces cellular senescence by upregulating CUX1 and p16INK4a"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing

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