Latest posts tagged with #QuorumSensing on Bluesky
Did you know?
Some bacteria can actually “talk” to each other using chemical signals, a process called quorum sensing.
By releasing and detecting tiny molecules, bacteria can sense how many of them are nearby.
#BiologyBytes #DidYouKnow #QuorumSensing
I don't use this platform enough for this to work, but by chance are there any microbiologists out there with Chromobacterium violaceum strains Cv017 and Cv026 for AHL quorum sensing? #microbiology #quorumsensing
Figure 2 Kumar (2026): In planta colonization experiment testing AG129 WT, AG129easI and AG129easI(pBBR1MCS3easI). Ten plants (n = 10) were used in each group of inoculations. A) Quantification of CFUs/g of root in the rhizosphere 7 days post inoculation. B) Quantification of CFUs/g of root in the endosphere 7 days post inoculation. To assess statistical significance, t-test was used. All data are presented as means ± standard error (SD). The error bars indicate standard deviations. GraphPad Prism 9.2 (GraphPad Software, Inc.) was used for statistical analysis. *P < 0.05 **P < 0.005, ***P < 0.0005, ****P < 0.00005 as indicated.
New publication: AHL quorum sensing regulates T6SS and volatiles production in #rice root-colonizing #Enterobacter asburiae AG129, by @PaolinaGarbeva and others. #bacteria #quorumsensing
doi.org/10.1093/fems...
New research from the Neiditch lab at Rutgers NJMS on the Vibrio cholerae CqsR receptor reveals how this pathogen monitors host-derived ethanolamine to successfully navigate and colonize the human gut.
go.njmicrobe.org/m6qAAa #VibrioCholerae #QuorumSensing #CacheDomain #StructuralBiology
Wow, I hadn't realised Nigel Franks didn't publish about this until 2015. He'd been talking about it as long as I'd been at Bath (since 2002), probably longer. Gives me hope for some of my own #cooperation work that's languishing.
IMO, #quorumSensing explains a LOT.
www.nature.com/articles/sre...
What a privilege attending yesterday the 30th Norman Heatley lecture hosted by @dunnschool.bsky.social to listen in person to my favourite scientist and role model Bonnie Bassler talking about the wonders of #quorumsensing, the topic I started working on as a PhD student and future microbiologist!
How Gut Bacteria Communicate: Information Transfer in Quorum Sensing
A study models gut bacteria quorum sensing as a communication channel and finds Firmicutes and Bacteroidetes retain measurable mutual information, indicating fidelity. Read more: getnews.me/how-gut-bacteria-communi... #quorumsensing #gutmicrobiome
But this all changed when I heard a lecture by @belindaferrari.bsky.social during my undergrad about #quorumsensing in bacteria, and how it enabled them to work together to do all sorts of cool things (like fluoresce as a light organ in squid!) and I thought that was the coolest concept ever!
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System architecture of quorum-sensing circuits. Top left: Quorum sensing in proteobacteria. A signal synthase (blue) produces a diffusible signal (black circles) that binds to a cytoplasmic signal receptor (light blue). When the signal reaches sufficient concentrations, it binds to and activates the receptor, which causes changes in transcription of target genes. Top right: The las and rhl systems of P. aeruginosa. The lasB gene is activated by both systems. The specific acyl-homoserine lactone signal molecule is pictured for each system. Bottom: Illustration of circuit architecture: reciprocal, hierarchical, and independent. Indicated below are the relative levels of lasB gene activation and sensitivity shown by Thomas and colleagues in experimental and modeling studies.
Many bacteria use #QuorumSensing to control genes based on population density. @jrchandler.bsky.social &co explore a @plosbiology.org study showing that in P. aeruginosa, 2 QS circuits activate each other, enhancing robustness & explaining redundancy 🧪 Paper: plos.io/3I7DhRG Primer: plos.io/4niSZZd
System architecture of quorum-sensing circuits. Top left: Quorum sensing in proteobacteria. A signal synthase (blue) produces a diffusible signal (black circles) that binds to a cytoplasmic signal receptor (light blue). When the signal reaches sufficient concentrations, it binds to and activates the receptor, which causes changes in transcription of target genes. Top right: The las and rhl systems of P. aeruginosa. The lasB gene is activated by both systems. The specific acyl-homoserine lactone signal molecule is pictured for each system. Bottom: Illustration of circuit architecture: reciprocal, hierarchical, and independent. Indicated below are the relative levels of lasB gene activation and sensitivity shown by Thomas and colleagues in experimental and modeling studies.
Many bacteria use #QuorumSensing to control genes based on population density. @jrchandler.bsky.social &co explore a @plosbiology.org study showing that in P. aeruginosa, 2 QS circuits activate each other, enhancing robustness & explaining redundancy 🧪 Paper: plos.io/3I7DhRG Primer: plos.io/4niSZZd
The las and rhl QS systems have a reciprocal, synergistic, and unequal relationship. Top: Single-signal models demonstrate that the summed effects of single signals (3 oxo C12 HSL alone, red; C4 HSL alone, orange) cannot account for the maximal expression of lasI or rhlI. The upper green, flat surfaces in the plots indicate the maximum mean expression level measured across all combinations of signal concentrations while the lower semi-transparent surfaces mark the sum of single signal effects. The plotted points represent observed expression levels when C4 HSL is withheld (red) and when 3 oxo C12 HSL is withheld (yellow). Lines indicate the model predictions. Bottom: Multi-signal non-linear models capture the synergistic effects of both signals and match observed expression levels. Model estimates are shown as grid lines. Horizontal bars show the mean value of expression observed at each combination of signal concentrations. Lines extend from these mean values to the relevant grid point for clarity. Right: Data show that relationship of the las and rhl systems is reciprocal, and the multi-signal model quantifies the strength of those interactions. In particular, it reveals the contribution of both signals to the maximum fold-change in expression of both synthases. The charts in this panel summarize the contribution of 3 oxo C12 HSL (red), C4 HSL (yellow), and the synergistic combination of both (orange).
Bacterial #QuorumSensing is often assumed to follow a strict hierarchy. @brownlab.bsky.social &co find that #Pseudomonas aeruginosa instead uses a reciprocal, cooperative system that enhances responsiveness to population density & environmental changes @plosbiology.org 🧪 plos.io/3I7DhRG
System architecture of quorum-sensing circuits. Top left: Quorum sensing in proteobacteria. A signal synthase (blue) produces a diffusible signal (black circles) that binds to a cytoplasmic signal receptor (light blue). When the signal reaches sufficient concentrations, it binds to and activates the receptor, which causes changes in transcription of target genes. Top right: The las and rhl systems of P. aeruginosa. The lasB gene is activated by both systems. The specific acyl-homoserine lactone signal molecule is pictured for each system. Bottom: Illustration of circuit architecture: reciprocal, hierarchical, and independent. Indicated below are the relative levels of lasB gene activation and sensitivity shown by Thomas and colleagues in experimental and modeling studies.
Many bacteria use #QuorumSensing to control genes based on population density. @jrchandler.bsky.social &co explore a @plosbiology.org study showing that in P. aeruginosa, 2 QS circuits activate each other, enhancing robustness & explaining redundancy 🧪 Paper: plos.io/3I7DhRG Primer: plos.io/4niSZZd
The las and rhl QS systems have a reciprocal, synergistic, and unequal relationship. Top: Single-signal models demonstrate that the summed effects of single signals (3 oxo C12 HSL alone, red; C4 HSL alone, orange) cannot account for the maximal expression of lasI or rhlI. The upper green, flat surfaces in the plots indicate the maximum mean expression level measured across all combinations of signal concentrations while the lower semi-transparent surfaces mark the sum of single signal effects. The plotted points represent observed expression levels when C4 HSL is withheld (red) and when 3 oxo C12 HSL is withheld (yellow). Lines indicate the model predictions. Bottom: Multi-signal non-linear models capture the synergistic effects of both signals and match observed expression levels. Model estimates are shown as grid lines. Horizontal bars show the mean value of expression observed at each combination of signal concentrations. Lines extend from these mean values to the relevant grid point for clarity. Right: Data show that relationship of the las and rhl systems is reciprocal, and the multi-signal model quantifies the strength of those interactions. In particular, it reveals the contribution of both signals to the maximum fold-change in expression of both synthases. The charts in this panel summarize the contribution of 3 oxo C12 HSL (red), C4 HSL (yellow), and the synergistic combination of both (orange).
Bacterial #QuorumSensing is often assumed to follow a strict hierarchy. @brownlab.bsky.social &co find that #Pseudomonas aeruginosa instead uses a reciprocal, cooperative system that enhances responsiveness to population density & environmental changes @plosbiology.org 🧪 plos.io/3I7DhRG
The las and rhl QS systems have a reciprocal, synergistic, and unequal relationship. Top: Single-signal models demonstrate that the summed effects of single signals (3 oxo C12 HSL alone, red; C4 HSL alone, orange) cannot account for the maximal expression of lasI or rhlI. The upper green, flat surfaces in the plots indicate the maximum mean expression level measured across all combinations of signal concentrations while the lower semi-transparent surfaces mark the sum of single signal effects. The plotted points represent observed expression levels when C4 HSL is withheld (red) and when 3 oxo C12 HSL is withheld (yellow). Lines indicate the model predictions. Bottom: Multi-signal non-linear models capture the synergistic effects of both signals and match observed expression levels. Model estimates are shown as grid lines. Horizontal bars show the mean value of expression observed at each combination of signal concentrations. Lines extend from these mean values to the relevant grid point for clarity. Right: Data show that relationship of the las and rhl systems is reciprocal, and the multi-signal model quantifies the strength of those interactions. In particular, it reveals the contribution of both signals to the maximum fold-change in expression of both synthases. The charts in this panel summarize the contribution of 3 oxo C12 HSL (red), C4 HSL (yellow), and the synergistic combination of both (orange).
Bacterial #QuorumSensing is often assumed to follow a strict hierarchy. @brownlab.bsky.social &co find that #Pseudomonas aeruginosa instead uses a reciprocal, cooperative system that enhances responsiveness to population density & environmental changes @plosbiology.org 🧪 plos.io/3I7DhRG
Princeton researchers uncover 30 inhibitors of the quorum-sensing receptor PqsR in P. aeruginosa. These compounds block virulence—without affecting growth—by silencing PqsE-RhlR pathways. go.njmicrobe.org/4vrZIT #QuorumSensing #Pseudomonas #Antivirulence #BasslerLab
Quorum sensing mediates morphology and motility transitions in the model archaeon Haloferax volcanii
#microbiology #archaea #QuorumSensing
@asm.org
journals.asm.org/doi/10.1128/...
Just published! Paula Mugica has standardized a set of #quorumsensing tools for its use in gramnegative bacteria. Their utility range from the development of #synbio #circuits inside a cell to what is even cooler: for cell to cell communication :) pubs.acs.org/doi/10.1021/...
SpO2 pode mensurar a cognição? 🤯
#icmpc18 #icmpc2025 #EEG #fNIRS #ERP #QuorumSensing #Educação #Saúde #Segurança #DeepFesbe2025 #SoberaniaDigital #DREX
neuroinsight.net/blog/spo2-po...
💡 E se saúde não fosse só remédio, mas também renda, sombra, água e tempo pra viver? 🏞️
#Neurociencia #MenteDamasiana #icmpc18 #icmpc2025 #EEG #fNIRS #ERP #QuorumSensing #Educação #Saúde #Segurança #DeepFesbe2025 #SoberaniaDigital #DREX
neuroinsight.net/blog/saude-i...
Pertencimento, Apus, Estado Dinâmico e Liberdade Radical
#FeSBE2025 #SaúdeMental #DREXcidadão #Existência #RitmoDeVida #Decolonial #Neuroscience #Neurociencia #MenteDamasiana #EEG #fNIRS #ERP #QuorumSensing #Educação #Saúde
neurosciencegrrl.net/blog/pertenc...
🐝Quorum Sensing na sala de aula: inteligência coletiva inspirada em bactérias! 🦠
#FeSBE2025 #SaúdeMental #DREXcidadão #Existência #RitmoDeVida #Decolonial #Neuroscience #Neurociencia #MenteDamasiana #EEG #fNIRS #ERP #QuorumSensing #Educação #Saúde
brainsupport.com.br/blog/educaca...
Ambiente escolar modifica genes? 🧬
Epigenética revela: escolas regenerativas reprogramam DNA.
#FeSBE2025 #SaúdeMental #DREXcidadão #Existência #RitmoDeVida #Decolonial #Neuroscience #Neurociencia #MenteDamasiana #EEG #fNIRS #ERP #QuorumSensing #Educação #Saúde
brainsupport.com.br/blog/educaca...
Winzig klein, doch hochkomplex: #Bakterien sind faszinierende Organismen. Mithilfe chemischer Signale - dem sogenannten #QuorumSensing - koordinieren sie ihr Verhalten & kommunizieren in Lebensgemeinschaften. Mehr bei @scifri.bsky.social im Podcast. www.sciencefriday.com/segments/bac...
Frank Santoriello showed how phage φVP882 make life-or-death decisions using bacterial quorum sensing. Depending on host density and whether cells are on a surface or in liquid, the phage toggles between lysis & lysogeny. For more: wix.to/1Cx2fsI #Microbiology #Princeton #PhageBiology #QuorumSensing
Educação Municipal
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brainsupport.com.br/blog/educaca...
FeSBE2025
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brainsupport.com.br/blog/visao-d...
FeSBE2025
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brainsupport.com.br/blog/visao-d...
El Día como Función La Noche como Significado – Cerrar para Hacer Abrir para Ser
#FeSBE2025
#SaúdeMental
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#Decolonial
#Neuroscience
#OHBM2025
#Neurociencia
#MenteDamasiana
#icmpc18
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#EEG
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brainlatam.com/blog/dia-y-n...
SAÚDE INTEGRAL DO MUNICÍPIO
#FeSBE2025
#SaúdeMental
#DREXcidadão
#Existência
#RitmoDeVida
#Decolonial
#Neuroscience
#OHBM2025
#EEG
#fNIRS
#ERP
#QuorumSensing
#Educação
#Saúde
#Segurança
#DeepFesbe2025
#SoberaniaDigital
#DemocraciaTerritorial
#DREX
brainlatamimages.com/blog/saude-i...
Saúde Municipal e Ciência - Deep Fesbe 2025
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#Segurança
#DeepFesbe2025
#SoberaniaDigital
#DREX
neuroinsight.net/blog/saude-m...
