Check out our review on the role of #retroelements and #viralmimicry during cancer treatment! @neoviral.bsky.social
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#Retroelements
Latest posts tagged with #Retroelements on Bluesky
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Posts tagged #Retroelements
Top left: Immunofluorescence images of anti-GFP (green) and anti-ATRX (red) counterstained with DAPI (blue) illustrating absence of ATRX in Sun1GFP+ microglia nuclei in 2-month-old ATRX miKO mice. Scale bar, 50 µm. Bottom left: Representative images of microglia tracings; Sholl analysis reveals excessive branching in ATRX miKO compared to control microglia. Right: Immunofluorescence staining of CD68 (green) and Ai14+ (red) cortical and hippocampal CA1 microglia. Scale bar, 50 µm.
What's the role of microglial chromatin-mediated processes? This study shows that loss of ATRX in #microglia disrupts #chromatin structure, leading to de-repression of #retroelements & a viral mimicry #inflammation response that impairs hippocampal neuron function @plosbiology.org 🧪 plos.io/46cBaE4
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Top left: Immunofluorescence images of anti-GFP (green) and anti-ATRX (red) counterstained with DAPI (blue) illustrating absence of ATRX in Sun1GFP+ microglia nuclei in 2-month-old ATRX miKO mice. Scale bar, 50 µm. Bottom left: Representative images of microglia tracings; Sholl analysis reveals excessive branching in ATRX miKO compared to control microglia. Right: Immunofluorescence staining of CD68 (green) and Ai14+ (red) cortical and hippocampal CA1 microglia. Scale bar, 50 µm.
What's the role of microglial chromatin-mediated processes? This study shows that loss of ATRX in #microglia disrupts #chromatin structure, leading to de-repression of #retroelements & a viral mimicry #inflammation response that impairs hippocampal neuron function @plosbiology.org 🧪 plos.io/46cBaE4
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Top left: Immunofluorescence images of anti-GFP (green) and anti-ATRX (red) counterstained with DAPI (blue) illustrating absence of ATRX in Sun1GFP+ microglia nuclei in 2-month-old ATRX miKO mice. Scale bar, 50 µm. Bottom left: Representative images of microglia tracings; Sholl analysis reveals excessive branching in ATRX miKO compared to control microglia. Right: Immunofluorescence staining of CD68 (green) and Ai14+ (red) cortical and hippocampal CA1 microglia. Scale bar, 50 µm.
What's the role of microglial chromatin-mediated processes? This study shows that loss of ATRX in #microglia disrupts #chromatin structure, leading to de-repression of #retroelements & a viral mimicry #inflammation response that impairs hippocampal neuron function @plosbiology.org 🧪 plos.io/46cBaE4
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We are hiring. Join us if you like the topic. Also, we’re nice and dedicated people here @immunosens.bsky.social @unibonn.bsky.social 🥸 Exiting times ahead in #immunosky & #retroelements
Funded by @erc.europa.eu
www.nature.com/naturecareer...
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Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer
👉 buff.ly/ikXlqbh
#ViralMimicry #Inflammation #HGSOC #Retroelements
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Could blocking ‘jumping genes’ help fight disease and #aging? #retrovirus #retroelements #3TC #HIV #HTLV www.science.org/content/arti...
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Congratulations Miguel @brancolab.bsky.social on your fantastic inaugural lecture as Professor of Genome Regulation @qmul.ac.uk "On the Versatility of Genomes". What a trip down memory lane from the good old days of me being your first postdoc working on #retroelements! Congratulations!!
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3) nuclear element (LINEs), they developed
a composite retroelement-Age clock called
➡️ “Retro-Age.”
The results support the idea that certain #retroelements in the human genome may be involved in aging.
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