#Rloop

Latest posts tagged with #Rloop on Bluesky

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Posts tagged #Rloop

Milo B. Fasken, Ph.D.

@milofasken.bsky.social

8 months ago

Cellular imbalance of specific RNA binding proteins associates with harmful R-loops Author summary R-loops are three-stranded structures formed by a DNA-RNA hybrid and the displaced ssDNA. The accumulation of R-loops damages the genome, highlighting the need for their tight regulatio...

#Dis3 #Rloop #RBP #RNAExosome #RNA

journals.plos.org/plosgenetics...

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Milo B. Fasken, Ph.D.

@milofasken.bsky.social

1 year ago

R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania - Nature Communications All genomes are replicated in a temporal order, though the determinants of such timing are poorly characterized. Here, the authors show that the unusual chromosome size-dependent DNA replication timin...

#Rloop #RNA #RNaseH1

www.nature.com/articles/s41...

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Milo B. Fasken, Ph.D.

@milofasken.bsky.social

1 year ago

The hidden weavers: A review of DNA/RNA R-loops in stem cell biology and therapeutic potential R-loops, three-stranded nucleic acid structures composed of RNA-DNA hybrids, are increasingly recognized as central regulators of genomic stability an…

#Rloop #RNADNAHybrid

www.sciencedirect.com/science/arti...

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Andrew Deans

@genomestability.bsky.social

7 years ago

DXH9 prevents #Rloop formation. Identified in a screen for proteins co-precipitating with S9.6 anti-DNA:RNA hybrid antibody. @CellReports
https://goo.gl/jjkaWL

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