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Elimination of visceral leishmaniasis as a public health problem in Bangladesh: Lessons learned and questions remaining Author summary In 2023, Bangladesh became the first country validated by the WHO for eliminating visceral leishmaniasis (kala-azar) as a public health problem—defined as having less than 1 case per…

#ScienceReadForSunday: Elimination of #VisceralLeishmaniasis as a public health problem in #Bangladesh: Lessons learned and questions remaining
journals.plos.org/plosntds/art...

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A new tool at a complex time for malaria decision making Malaria remains a major global health challenge, with an estimated 282 million new cases and 610 000 deaths in 2024.1 Although substantial progress has been made through a variety of treatment and…

#ScienceReadForSunday: A new tool at a complex time for malaria decision making
www.thelancet.com/journals/lan...

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Biochemical profiling provides a low-cost and globally accessible method to detect falsified vaccines and insulin - Scientific Reports For many decades, there have been numerous reported cases of falsified liquid medical products, including vaccine and insulin preparations worldwide, but to date, there has been a lack of affordable…

#ScienceReadForSunday: Biochemical profiling provides a low-cost and globally accessible method to detect falsified vaccines and insulin
www.nature.com/articles/s41...

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Probabilistic classification of late treatment failure in uncomplicated falciparum malaria - Nature Communications Distinguishing treatment failure from reinfection is crucial for assessing antimalarial efficacy in endemic regions. Here the authors introduce the probabilistic classifier PfRecur, a software…

#ScienceReadForSunday: Probabilistic classification of late treatment failure in uncomplicated #falciparum #malaria
www.nature.com/articles/s41...

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A cross-sectional survey of Plasmodium falciparum and Plasmodium vivax in India using rapid diagnostic test and microscopy across 12 sites of varying transmission, 2023–2024 - Malaria Journal Background In India, Plasmodium falciparum and Plasmodium vivax remain in circulation. Accurate detection of the parasite species remains crucial for prompt initiation of treatment and reducing…

#ScienceReadForSunday: A cross-sectional survey of Plasmodium #falciparum and Plasmodium #vivax in India using rapid diagnostic test and microscopy across 12 sites of varying transmission, 2023–2024 #malaria
link.springer.com/article/10.1...

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Epidemiological Shifts in Visceral Leishmaniasis Incidence, Relapse, and Mortality in Brazil, 2007–2023: Analysis Using the National Notifiable Diseases Information System AbstractBackground. Brazil accounts for >90% of visceral leishmaniasis (VL) cases reported in South America. VL is a notifiable disease in Brazil and pa

#ScienceReadForSunday: Epidemiological Shifts in #VisceralLeishmaniasis Incidence, Relapse, and Mortality in #Brazil, 2007–2023: Analysis Using the National Notifiable Diseases Information System
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Moving towards high-dose primaquine or single-dose tafenoquine for Plasmodium vivax treatment in Cambodia: a meeting report from dissemination of results of the EFFORT trial to stakeholders - Malaria Journal Cambodia has targeted malaria elimination by 2025. As the malaria burden has decreased in Cambodia, transmission has become more focal, and Plasmodium vivax has become the predominant species. The…

#ScienceReadForSunday: Moving towards high-dose primaquine or single-dose tafenoquine for Plasmodium vivax treatment in Cambodia: a meeting report from dissemination of results of the EFFORT trial to stakeholders #malaria
link.springer.com/article/10.1...

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Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas’ disease drug discovery Author summary Chagas’ disease, a consequence of infection with the parasite Trypanosoma cruzi, is a severe global health problem. Most of the 6–7 million infected individuals reside in Latin America…

#ScienceReadForSunday: Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas’ disease drug discovery
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Model-guided geospatial surveillance system for antimalarial drug resistance Disease surveillance activities are usually resource-constrained and should be optimised to generate the most informative scientific findings, and to make the best use of time, finances, and…

#ScienceReadForSunday: Model-guided geospatial surveillance system for antimalarial drug resistance #malaria
journals.plos.org/globalpublic...

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Model-guided geospatial surveillance system for antimalarial drug resistance Disease surveillance activities are usually resource-constrained and should be optimised to generate the most informative scientific findings, and to make the best use of time, finances, and…

#ScienceReadForSunday: Model-guided geospatial surveillance system for antimalarial drug resistance #malaria
journals.plos.org/globalpublic...

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A systematic review and meta-analysis of the impact of vaccination on prevention of long COVID - Nature Communications This meta-analysis demonstrates that people who received COVID-19 vaccination had a lower risk of long COVID compared with those who were unvaccinated during the Omicron era, with booster doses…

#ScienceReadForSunday: A systematic review and meta-analysis of the impact of vaccination on prevention of long #COVID
www.nature.com/articles/s41...

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Probabilistic classification of late treatment failure in uncomplicated falciparum malaria - Nature Communications Distinguishing treatment failure from reinfection is crucial for assessing antimalarial efficacy in endemic regions. Here the authors introduce the probabilistic classifier PfRecur, a software…

#ScienceReadForSunday: Probabilistic classification of late treatment failure in uncomplicated falciparum malaria
www.nature.com/articles/s41...

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#ScienceReadForSunday: Prospective characterisation of drug-resistant bloodstream infections in Africa and Asia (ACORN2): a surveillance network assessment @TropMedOxford @LOMRU

www.thelancet.com/journals/lan...

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Model-guided geospatial surveillance system for antimalarial drug resistance Disease surveillance activities are usually resource-constrained and should be optimised to generate the most informative scientific findings, and to make the best use of time, finances, and…

#ScienceReadForSunday: Model-guided geospatial surveillance system for antimalarial drug resistance
journals.plos.org/globalpublic...

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Analysis of Phlebotomine sandflies in Laos from 2014–2024: Inventory, description of a new species, screening for Leishmania and detection of Trypanosoma Author summary Phlebotomine sandflies are best known as insect vectors of arboviruses and leishmaniasis, a parasitic disease of global health concern. While neighboring Thailand has reported locally…

#ScienceReadForSunday: Analysis of Phlebotomine sandflies in Laos from 2014–2024: Inventory, description of a new species, screening for Leishmania and detection of Trypanosoma @TropMedOxford #LOMWRU
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The effects of introduced procedural errors on malaria rapid diagnostic test performance in a laboratory setting - Malaria Journal Background Rapid Diagnostic Tests (RDTs) are the primary means of malaria diagnosis in sub-Saharan Africa. Outside large health facilities, individuals performing RDTs have little or no formal…

#ScienceReadForSunday: The effects of introduced procedural errors on malaria rapid diagnostic test performance in a laboratory setting @malariaJournal @CDCgov
link.springer.com/article/10.1...

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Prevalence, intensity, and risk factors of schistosomiasis and intestinal parasitic infections among primary school children in northern Uganda: Implications for public health interventions Author summary Schistosomiasis and intestinal parasitic infections are significant public health challenges, especially in low-resource settings like Northern Uganda. These infections can lead to…

#ScienceReadForSunday: Automated reporting of primaquine dose efficacy, tolerability and safety for #Plasmodium #vivax #malaria using a systematic review and individual patient data meta-analysis
journals.plos.org/plosntds/art...

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Mapping Plasmodium transitions and interactions in the Anopheles female - Nature Single-cell transcriptomic analyses of Plasmodium falciparum and Anopheles gambiae reveal key developmental stages, processes and factors in parasite–mosquito interactions and identify potential…

#ScienceReadForSunday: Mapping Plasmodium transitions and interactions in the Anopheles female #malaria
www.nature.com/articles/s41...

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Prevalence, intensity, and risk factors of schistosomiasis and intestinal parasitic infections among primary school children in northern Uganda: Implications for public health interventions Author summary Schistosomiasis and intestinal parasitic infections are significant public health challenges, especially in low-resource settings like Northern Uganda. These infections can lead to…

#ScienceReadForSunday: #ScienceReadForSunday: Automated reporting of primaquine dose efficacy, tolerability and safety for #Plasmodium #vivax #malaria using a systematic review and individual patient data meta-analysis
journals.plos.org/plosntds/art...

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Prevalence, intensity, and risk factors of schistosomiasis and intestinal parasitic infections among primary school children in northern Uganda: Implications for public health interventions Author summary Schistosomiasis and intestinal parasitic infections are significant public health challenges, especially in low-resource settings like Northern Uganda. These infections can lead to…

#ScienceReadForSunday: Prevalence, intensity, and risk factors of #schistosomiasis and intestinal parasitic infections among primary school children in northern Uganda: Implications for public health interventions
journals.plos.org/plosntds/art...

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Rapid screening of ethylene glycol and diethylene glycol in raw materials and medicinal syrups using low-cost field deployable assays - Scientific Reports There have been hundreds of child deaths due to contamination of medicinal syrups with diethylene glycol (DEG) and ethylene glycol (EG). Detection of DEG and EG is usually performed by gas…

#ScienceReadForSunday: Rapid screening of ethylene glycol and diethylene glycol in raw materials and medicinal syrups using low-cost field deployable assays
www.nature.com/articles/s41...

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Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis - Malaria Journal Background The antirelapse efficacy of primaquine is related to the total dose administered, whereas the risks of haemolysis and gastrointestinal intolerance are associated with the daily dose…

#ScienceReadForSunday: Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis
link.springer.com/article/10.1...

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Rethinking a hybrid malaria chemoprevention delivery strategy for children in sub-perennial settings: a modelling study integrating age- and seasonally-targeted delivery - Malaria Journal Background The World Health Organization recommends perennial malaria chemoprevention (PMC), generally using sulfadoxine-pyrimethamine (SP) to children at high risk of severe Plasmodium falciparum…

#ScienceReadForSunday: Rethinking a hybrid malaria chemoprevention delivery strategy for children in sub-perennial settings: a modelling study integrating age- and seasonally-targeted delivery
link.springer.com/article/10.1...

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Probabilistic classification of late treatment failure in uncomplicated falciparum malaria - Nature Communications Distinguishing treatment failure from reinfection is crucial for assessing antimalarial efficacy in endemic regions. Here the authors introduce the probabilistic classifier PfRecur, a software…

#ScienceReadForSunday: Probabilistic classification of late treatment failure in uncomplicated #falciparum #malaria
www.nature.com/articles/s41...

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The development of a global research agenda and individual participant data platform for visceral leishmaniasis: challenges and future opportunities - Parasites & Vectors Background Visceral leishmaniasis (VL) is one of the neglected tropical diseases (NTDs) listed by the World Health Organization (WHO). The disease is currently in the elimination phase in the Indian…

#ScienceReadForSunday: The development of a global research agenda and individual participant data platform for visceral leishmaniasis: challenges and future opportunities
link.springer.com/article/10.1...

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Probabilistic classification of late treatment failure in uncomplicated falciparum malaria - Nature Communications Distinguishing treatment failure from reinfection is crucial for assessing antimalarial efficacy in endemic regions. Here the authors introduce the probabilistic classifier PfRecur, a software…

#ScienceReadForSunday: Probabilistic classification of late treatment failure in uncomplicated #falciparum #malaria
www.nature.com/articles/s41...

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A cross-sectional survey of Plasmodium falciparum and Plasmodium vivax in India using rapid diagnostic test and microscopy across 12 sites of varying transmission, 2023–2024 - Malaria Journal Background In India, Plasmodium falciparum and Plasmodium vivax remain in circulation. Accurate detection of the parasite species remains crucial for prompt initiation of treatment and reducing…

#ScienceReadForSunday: A cross-sectional survey of Plasmodium falciparum and Plasmodium vivax in India using rapid diagnostic test and microscopy across 12 sites of varying transmission, 2023–2024
link.springer.com/article/10.1...

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Long-term outcomes of benznidazole treatment in chronic Chagas disease: A 27-year cohort study of parasitological cure and death in the Jequitinhonha Valley, Brazil Author summary Chagas disease is a common parasitic disease that occurs mainly in poor regions of countries with low development rates of Latin America, including Brazil. According to the World…

#ScienceReadForSunday: Long-term outcomes of benznidazole treatment in chronic #Chagas disease: A 27-year cohort study of parasitological cure and death in the Jequitinhonha Valley, Brazil
journals.plos.org/plosntds/art...

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Mapping Plasmodium transitions and interactions in the Anopheles female - Nature Single-cell transcriptomic analyses of Plasmodium falciparum and Anopheles gambiae reveal key developmental stages, processes and factors in parasite–mosquito interactions and identify potential…

#ScienceReadForSunday: Mapping Plasmodium transitions and interactions in the Anopheles female
www.nature.com/articles/s41...

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Mapping Plasmodium transitions and interactions in the Anopheles female - Nature Single-cell transcriptomic analyses of Plasmodium falciparum and Anopheles gambiae reveal key developmental stages, processes and factors in parasite–mosquito interactions and identify potential…

#ScienceReadForSunday: Mapping Plasmodium transitions and interactions in the Anopheles female
www.nature.com/articles/s41...

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