JAMA Network Open presents RCT: Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery. Population: 210 men, 172 women. Intervention: 424 patients randomized, 382 analyzed. Findings show Sivelestat reduced ARDS compared to placebo.
In patients undergoing cardiovascular surgery with cardiopulmonary bypass, postoperative infusion with #Sivelestat significantly reduced the incidence of #ARDS and 90-day mortality compared with placebo.
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