Latest posts tagged with #Squamous on Bluesky
can enrich for this #hillock-like state. We identify surface markers that can be explored as ways to target the hillock-like state, which we think will be important to fully eradicate #squamous cancers. A companion manuscript identified #Tmprss11b as a #KLF4-regulated hillock gene impacting the TME.
Transcriptional plasticity is a major barrier to effective cancer treatment. We know a lot about it in #SCLC but less is known for #squamous #lungcancer. Luke Izzo & Tony Reyes have made major inroads into this problem in our latest preprint:
pubmed.ncbi.nlm.nih.gov/40161723/
Alarming…
#melanoma #basal #squamous #cell #carcinoma #skin #cancer #dermatology #australia
www.bbc.com/news/article...
The oncologist told me that he does not think there might be a metastasis based on my intermittent mild pain in the nose. I wonder if there are good biomarkers of #HPV-associated #squamous cell #cancer of the nasal vestibule.
Looking for the latest info about mets squamous cell skin cancer.
Who is doing the most innovative protocols with the least amount of side effects - specially around shrinking a tumor ahead of surgery + immunotherapy?
#squamous #cancer
Mechanistically, we find that #KLF4 is key, driving a shift from basal-like to hillock-like states. Our findings shed light on how cancer progression mirrors normal tissue development. We hope this work paves the way for cell state-specific therapies for #squamous lung cancer.
Schematic showing single cell RNA-seq from human squamous tumors, mouse models and tumor organoids. A second graphic shows a model of squamous lung cancer heterogeneity where KLF4 promotes basal cells to adopt a KRT13+ hillock-like state.
#Squamous #lungcancer cells aren’t all alike — the tumor is a mix of distinct cancer cell states! @lukeizzo.bsky.social & Oliver lab uncover #KRT13+ hillock-like, slow-dividing, immunomodulatory tumor cells that resemble the recently discovered normal lung #hillock cells (Lin et al, Nature, 2024).
POGOPHAGE (Monday lunchtime motion sketch 💀) #monster #animation #encounter #dungeoncrawl #rpg #squamous #aftereffects #ae #design #illustration #film
Perineural Invasion Is Associated With function-evoked #pain and altered extracellular matrix in #patients with head and neck #squamous cell carcinoma 🔬 #cancerpain #Perineuralinvasion #HNSCC #FunctionevokedPain www.sciencedirect.com/science/arti...
The Long Night- A Dwarf Fortress mod by Squamous.
This is the commercial that I made for it in my last CoQ episode. This is what i'm doing now I guess.
Long Night mod on Steam: steamcommunity.com/sharedfiles/...
#commercial #90s #DwarfFortress #mod #squamous #radical #TheLongNight #Longnight
Prof. Neil Gross #Surgical #oncology expert @mdanderson.bsky.social talks Future of surg onc & data/role for #neoadjuvant #immunotherapy for #squamous cell #carcinoma #SCC / post Tx cheek tumor was mostly scab/Only 5mm viable tu #Bridge2024 @sitcancer.bsky.social #FinishCancer
