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Register now to attend Dr. D J Christopher's talk on TB Elimination in India: The Challenges

ucsf.zoom.us/meeting/regi...

📅 March 19, 2026, at 8 am PDT

Hosted by the UCSF Institute for Global Health Sciences

#Tuberculosis #EndTB #TBSky

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March cover of The Lancet Microbe

March cover of The Lancet Microbe

Our March issue is now online:

www.thelancet.com/journals/lan...

Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #malaria #HIV #Streptococcus #PCV #RiftValleyFever #pertussis #tuberculosis #TB #AMR

#IDSky #ClinMicro #TBSky #OA

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New from AHRI in @jem.org AND on the cover!

📸 shows a human TB granuloma in lung tissue. The red, green & yellow cells shown, for example, are all different type of macrophage - immune cells that fight infection by engulfing & killing microbes like Mtb

#TBSky #IDSky

🔗 rupress.org/jem/article/...

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Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology Single-cell and spatial transcriptomics of human TB lung tissues from individuals in South Africa revealed that MMP1+CXCL5+ fibroblasts and SPP1+ macrophag

Played a small part in this cool study @jem.org.

Identifies myofibroblasts as sources of tissue damaging enzymes (MMP1) in TB granuloma, probably responding to cytokine cues from nearby macrophages.

Question now is: can we target therapeutically to prevent post-TB lung damage?

#TBSky #IDSky

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TBFighters are on the Hill today, advocating for increased funding to fight TB! Join us and help amplify our work by using @pih.org's tool to contact your representatives: https://act.pih.org/tb-funding-2026 
#TBHillDay #TBSky #IDSky

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El 18 de Marzo celebramos en Sevilla la IX Jornada de TB celebrando el día mundial de la TB. La inscripción es gratuita. Será presencial y on line simultáneamente. Os animamos a participar
#Tuberculosis #TBSky

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A great tool to be used in remote settings for countries having limited resources. Hoping for a quicker roll out now. #TBSky

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Unsurprising yet still depressing
#TBSky #IDSky

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🧪 Join us at the TB GAPS iECHOHub on Weds, 25 Feb for a presentation on Computer‑aided detection for pediatric TB, an emerging area of interest with unique diagnostic challenges and questions about performance, limitations, and appropriate use.
Register here: buff.ly/mIgT5ff
#GlobalHealth #TBSky

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#WorldDayofSocialJustice calls for equal access to healthcare. TB disproportionately affects marginalized communities, highlighting the urgent need for inclusive health policies. Let's work towards a fair and healthy world for everyone. #HealthForAll #TBSky

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New research article

#Bedaquiline resistance in patients with Xpert MTB/RIF Ultra-tested #rifampicin resistant #tuberculosis in the Western Cape, South Africa: a prospective study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #TBSky #TB #AMR #OpenAccess #OA

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Optimized Mass Spectrometry to Uncover M. tuberculosis Biomarkers in Extracellular Vesicles from Asymptomatic Tuberculosis Patients We used novel mass spectrometry to discover Mtb peptides in EV-enriched human serum samples. We found previously described and novel Mtb peptides. These fi

Quite clever how you can detect Mycobacterial antigens in extracellular vehicles in blood during asymptomatic TB.

Useful as biomarkers but maybe also to work out in vivo what are early / most abundant Mtb antigens produced.

#TBSky

academic.oup.com/jid/advance-...

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Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis - The EMBO Journal Bacterial pathogens must withstand metal-induced stress during infection, yet the mechanisms by which they sense and respond to toxic metal ions remain incompletely understood. Here, we uncover a prev...

Mycobacterium tuberculosis is so evolved at surviving environmental stresses!

By @oneyrolles.bsky.social & team
#TBSky #MicroSky @embojournal.org

link.springer.com/article/10.1...

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An incredible FOUR MILLION DOLLARS will be distributed to worthy charities bc of the #P4A2026 and there's still time to vote who will get the funds! If you, like us, are looking for some #Tuberculosis fighting causes to support, here are some you can vote for (& you can vote multiple times):
#TBSky

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Taking Side Effects Seriously | Nausea & Vomiting | Curry International Tuberculosis Center

Taking Side Effects Seriously | Nausea & Vomiting National Webinar
Monday, March 30, 2026
12:00 - 1:30 pm Pacific Time

www.currytbcenter.ucsf.edu/trainings/ta...

#Tuberculosis #CurryTBCenter #TB #SideEffects #TBSky

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Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

1/📢 In our new publication, we estimate that in 2022, 134 million people worldwide had a recent Mycobacterium tuberculosis (Mtb) infection and were at high risk of progressing to TB disease. Read the full paper in PLOS Medicine (tinyurl.com/mtbinfection). #TBSky

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Such a fun collaboration with @mel-foulon.bsky.social from the TS lab 🤝-👀 We combined dual RNA-Seq 🧬 and advanced imaging 🔬 to uncover how intracellular compartmentalization drives niche-specific metabolic phenotypes in mycobacteria!!
Fantastic team effort ✨
#Tbsky #microsky

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30 Years of Progress in Pediatric Tuberculosis (and So Much More to Do) - Ann Loeffler, MD (4/17/25)
30 Years of Progress in Pediatric Tuberculosis (and So Much More to Do) - Ann Loeffler, MD (4/17/25) YouTube video by UCSF Pediatrics

The current #tuberculosis #outbreak at a high school in SF is an important reminder of the advances and ongoing needs for child and adolescent TB; check out the recent @ucsfchildrens.bsky.social grand rounds on #childtb: youtu.be/RiOt70vekHI?...
#idsky #tbsky

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New investment brings TB testing closer to communities GHIT Fund invests USD 1.8 million to support research on the Lung Flute ECO

Tooting our own horn (again)🫁: www.itg.be/en/health-st... #TBsky #TB @itmantwerp.bsky.social @djaganath.bsky.social #EndTB#IDxPost#IDSky

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Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQlYlP

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Mycobacterium tuberculosis Transmission in Healthcare Settings: A Systematic Review of Frequency, Risk Factors, and Exposure Conditions This systematic review of 86 studies and 35,698 exposures suggests M. tuberculosis transmission in healthcare is rare; 93% of reported transmissions were a

TB transmission in healthcare is thankfully rare. Good to get some metrics of what are the highest risk exposures (that are worth following up).

#IDSky #TBSky
@cidjournal.bsky.social
academic.oup.com/cid/advance-...

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Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQjZ0W

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Concerning #IDSky #TBSky

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The effects of war on digital adherence technology engagement for TB treatment in Ukraine The Russian invasion of Ukraine in February 2022 has disrupted TB care. We examine the effects of the war on people with drug-susceptible TB (PWTB) and health care worker (HCW) engagement with a digital adherence technology (DAT). We conducted a ...

What is the effect of #war on people with #tuberculosis?🚨

Our recent publication suggests that the effect of war is neither instantaneous nor uniform.👈 #TBSky #TB

pmc.ncbi.nlm.nih.gov/articles/PMC...

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An image of the next TB Ed Talks speaker, Dr. Salmaan Keshavjee, with information about his talk. "Search-Treat-Prevent: A Strategy to Eliminate TB, with Dr. Salmaan Keshavjee. Professor of Global Health and Social Medicine, Medical Anthropology at Harvard Medical School; Director of Harvard Medical School's Center for Global Health Delivery; a founder of the Zero TB Initiative. Live presentation on YouTube followed by a Q&A. Wednesday, January 28th. 8pm ET/1am GMT."

An image of the next TB Ed Talks speaker, Dr. Salmaan Keshavjee, with information about his talk. "Search-Treat-Prevent: A Strategy to Eliminate TB, with Dr. Salmaan Keshavjee. Professor of Global Health and Social Medicine, Medical Anthropology at Harvard Medical School; Director of Harvard Medical School's Center for Global Health Delivery; a founder of the Zero TB Initiative. Live presentation on YouTube followed by a Q&A. Wednesday, January 28th. 8pm ET/1am GMT."

Tomorrow is 2026's first TB Ed Talk with Dr. Salmaan Keshavjee! Tune in to learn about Search-Treat-Prevent: a strategy to eliminate #Tuberculosis. Watch with us here: https://www.youtube.com/live/iiw9EqjWFrg
#IDSky #TBSky

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A “Just Transition” for Drug-Resistant Tuberculosis | Public Humanities | Cambridge Core A “Just Transition” for Drug-Resistant Tuberculosis - Volume 1

Person‑centred TB care is holistic, individualized, respectful and empowering.
A new KNCV publication argues this shift is only the start of a just transition for DR‑TB, urging us to ask: Who sets the agenda? Who benefits? And who is left behind?
#TBSky #TB #DRTB @universitypress.cambridge.org

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An image of the next TB Ed Talks speaker, Dr. Salmaan Keshavjee, with information about his talk. "Search-Treat-Prevent: A Strategy to Eliminate TB, with Dr. Salmaan Keshavjee. Professor of Global Health and Social Medicine, Medical Anthropology at Harvard Medical School; Director of Harvard Medical School's Center for Global Health Delivery; a founder of the Zero TB Initiative. Live presentation on YouTube followed by a Q&A. Wednesday, January 28th. 8pm ET/1am GMT."

An image of the next TB Ed Talks speaker, Dr. Salmaan Keshavjee, with information about his talk. "Search-Treat-Prevent: A Strategy to Eliminate TB, with Dr. Salmaan Keshavjee. Professor of Global Health and Social Medicine, Medical Anthropology at Harvard Medical School; Director of Harvard Medical School's Center for Global Health Delivery; a founder of the Zero TB Initiative. Live presentation on YouTube followed by a Q&A. Wednesday, January 28th. 8pm ET/1am GMT."

Only a few days until 2026's first TB Ed Talk with Dr. Salmaan Keshavjee! Tune in to learn about Search-Treat-Prevent: a strategy to eliminate #Tuberculosis. Submit questions at the link below or ask questions live: https://forms.gle/nyS52pM93bwathQ66
#IdSky #TBSky

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Register today!
Complex Contact Investigations

Postgraduate course sponsored by all four TB COEs as part of the 30th Annual Conference of The Union-North America Region

web.cvent.com/event/ed3744...

📅February 25, 2026
📍Philadelphia, PA

#EndTB #TBSky #Tuberculosis #CurryTBCenter @theunion.org

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New personal view article

Controlled human infection with #Mycobacterium #tuberculosis: practical considerations for clinical trials

www.thelancet.com/journals/lan...

#ClinMicro #IDSky #TBSky #TB #CHIM #OpenAccess #OA

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Registration Open! The Evolving Landscape of Laboratory Testing for Tuberculosis - Webinar

📅 February 12

💻 www.currytbcenter.ucsf.edu/trainings/ev...

#CurryTBCenter #Tuberculosis #GotCurry #TBSky

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