#microsky

E. coli outbreak linked to raw cheese. See affected products, states. The ongoing outbreak has sickened people across at least three states, according to the FDA.

1 hour ago

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Ordinary differential equation models of SARS-CoV-2 replication dynamics and antiviral drug efficacies - npj Viruses npj Viruses - Ordinary differential equation models of SARS-CoV-2 replication dynamics and antiviral drug efficacies

9 hours ago

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Clostridia from preterm infants metabolize human milk oligosaccharides to suppress pathobionts and modulate intestinal function in organoids - Nature Microbiology Clostridium perfringens lacking perfringolysin O toxin isolated from preterm infants metabolizes human milk oligosaccharide disialyllacto-N-tetraose to produce metabolites that promote the growth of c...

11 hours ago

#microsky #microbiomesky #microbiome

From Chris Stewart’s lab with a sialic acid twist

www.nature.com/articles/s41...

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Nature Microbiology

@natmicrobiol.nature.com

15 hours ago

Clostridia from preterm infants metabolize human milk oligosaccharides to suppress pathobionts and modulate intestinal function in organoids Nature Microbiology, Published online: 16 March 2026; doi:10.1038/s41564-026-02297-4Clostridium perfringens lacking perfringolysin O toxin isolated from preterm infants metabolizes human milk oligosaccharide disialyllacto-N-tetraose to produce metabolites that promote the growth of commensal bifidobacteria, inhibit pathogens and suppress inflammation in an organoid model.

Out Now! Clostridia from preterm infants metabolize human milk oligosaccharides to suppress pathobionts and modulate intestinal function in organoids #MicroSky

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Nature Microbiology

@natmicrobiol.nature.com

15 hours ago

Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19 Nature Microbiology, Published online: 16 March 2026; doi:10.1038/s41564-026-02285-8Longitudinal metatranscriptomics in a prospective cohort of 1,164 adults hospitalized for COVID-19 reveals that azithromycin offered no apparent anti-inflammatory benefit but enriched the respiratory microbiome with potential pathogens and antimicrobial resistance genes.

Out Now! Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19 #MicroSky

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Vivek Mutalik

@vivekmutalik.bsky.social

15 hours ago

#microsky

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Rebecca Drummond 🍄

@therad-lab.bsky.social

16 hours ago

Two people have died from bacterial meningitis in the UK. An expert answers your questions Two people have died in a bacterial meningitis outbreak in the south of England. Here’s what you need to know.

Worried about the #meningitis outbreak in the UK? I've answered some common questions in this @uk.theconversation.com article:
theconversation.com/two-people-h...
#immunosky #microsky 🧪

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AMI Journals

@ami-journals.bsky.social

16 hours ago

Prevention of food spoilage and the control of foodborne diseases remain major challenges for the food industry. A new study evaluates the antibacterial and antibiofilm activities of hazelnut skin extract (HSE) against spoilage bacteria and foodborne pathogens.

https://ow.ly/Vh1u50Yreiu

#Microsky

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Biomedical Journal

@biomedj.bsky.social

17 hours ago

CRISPR-Cas9-mediated elimination of plasmid-borne #carbapenemase genes restores ertapenem susceptibility in clinical #Klebsiella pneumoniae isolates

www.sciencedirect.com/science/arti... #OpenAccess #MicroSky

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TRAstonDrs

@castltrastondrs.bsky.social

17 hours ago

#Medsky🧪 #IDsky #microsky #publichealth @ukhsa.bsky.social #Meningococcaldisease ( #meningitis & #septicaemia) is an uncommon but serious disease caused by meningococcal bacteria.
Very occasionally, the )meningococcal bacteria can cause serious illness,

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#microsky #phagesky #phage

17 hours ago

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Microbial Biotechnology (MBT)

@microbiotech.bsky.social

19 hours ago

#MicroSky: Chronic Spontaneous Urticaria (CSU) is linked to gut dysbiosis and elevated serum uric acid/hypoxanthine. Lactobacillus paragasseri LG-1 alleviates urticaria by degrading these metabolites, inhibiting TLR4-NF-κB inflammation, and remodeling gut microbiota. doi.org/10.1111/1751...

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A modular biodevice assembly tool kit for combinatorial screening and benchmarking multiple cell surface display platforms in Escherichia coli - Journal of Biological Engineering Journal of Biological Engineering - Bacterial cell surface display is a versatile platform technology for synthetic biology applications. A successful display platform often requires ad hoc testing...

1 day ago

#microsky #synbiosky

link.springer.com/article/10.1...

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Iowa respiratory virus activity stays high as flu and RSV rise, COVID-19 continues to fall Respiratory virus activity in Iowa remained high but showed mixed trends during the week ending March 7, according to the Iowa Department of Health and Human Se

1 day ago

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Current Research in Microbial Sciences

@microbesinfect.bsky.social

1 day ago

Therapeutic challenges & Emerging Strategies against #Carbapenem -Resistant #Acinetobacter baumannii.

Emerging agents like sulbactam‑durlobactam, eravacycline & cefiderocol offer new options against multifaceted CRAB resistance.

www.sciencedirect.com/science/arti... #OpenAccess #MicroSky

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Cross-domain metabolic interactions link Methanobrevibacter smithii to colorectal cancer microbial ecosystems - Nature Communications Here, the authors identify widespread disease associations of gut archaea, particularly in colorectal cancer, with further experiments revealing Methanobrevibacter smithii cooperation with cancer-asso...

1 day ago

Cross-domain metabolic interactions link Methanobrevibacter smithii to colorectal cancer microbial ecosystems
#microbiology #methanogens #methane #cancer #ColorectalCancer #MicroSky #ArchaeaSky
@natcomms.nature.com
doi.org/10.1038/s414...

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Crystal structure of methanogen MtxX (Methanogen Marker Protein MMP4) from Methanothermobacter thermautotrophicus ΔH Structural analysis of the methanogen protein MtxX.

1 day ago

Crystal structure of methanogen MtxX (Methanogen Marker Protein MMP4) from Methanothermobacter thermautotrophicus ΔH
#microbiology #methanogens #methane #MicroSky #ArchaeaSky
@femsjournals.bsky.social @femsmicro.org
doi.org/10.1093/fems...

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@bacteriophile.bsky.social

1 day ago

High stability of the genome of Akkermansia muciniphila MucT under long-term culturing conditions
#microbiology #bacteria #MicroSky
@asm.org
doi.org/10.1128/spec...

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Animalcules

1 day ago

#Microsky

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@castltrastondrs.bsky.social

1 day ago

Acetogens beyond gas fermentation: Enhancing bioconversion of lignocellulosic biomass
#microbiology #acetogens #bacteria #biotechnology #MicroSky
doi.org/10.1016/j.bi...

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TRAstonDrs

1 day ago

Memory loss is fuelled by gut microbes in ageing mice If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline.

#Medsky🧪 #Neurosky #microsky #publichealth Progressive decreases in the ability to learn and remember are a normal consequence of healthy ageing. Severe cognitive decline is also seen in ageing-associated conditions such as #dementia .

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Animalcules

@bacteriophile.bsky.social

1 day ago

Translocation of bacteria from the gut to the brain in mice Recent studies link gut dysbiosis to neurological disease, but the underlying mechanisms remain unclear. This study shows that a high-fat diet increases gut permeability and enables bacterial transloc...

journals.plos.org/plosbiology/...

#microsky

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Vaccinating bats could be good for people. But how do you vaccinate a bat? In a new study, bats lap up vaccine-laced saline or chow down on vaccine-carrying mosquitoes. Will that have any impact on the flying mammal's immune system?

1 day ago

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Cross-family and phage-specific gene requirements for Klebsiella infection revealed by scalable RB-TnSeq genetic screens Bacteriophages (phages) are being cataloged at unprecedented rates and are recognized as key players in nutrient and energy cycling across ecosystems. Yet, the biological determinants of phage-host specificity and infection success remain poorly understood. Here, we used a randomly barcoded, genome-wide, loss-of-function transposon mutant library (RB-TnSeq) of Klebsiella sp. M5al, a plant-associated, nitrogen-fixing rhizobacterium, to identify bacterial genetic determinants necessary for the infection of 25 double-stranded DNA phages spanning five viral families. This approach identified 42 bacterial genes associated with phage infection, encompassing genes involved in receptor biosynthesis, regulatory pathways, electron transport, and unknown functions. Disruption of genes involved in receptor biosynthesis, such as glycosyltransferases involved in lipopolysaccharide (LPS) production, conferred cross-resistance to half of the phages, while intracellular gene disruptions had phage-specific effects. Taxonomically, we found significant differences in RB-TnSeq profiles across phage families and genera. While bacterial gene requirements are generally clustered by phage genus, we also observed notable divergences within genera. These differences were associated with variation in receptor usage, likely driven by divergence in tail fiber or other host recognition proteins. In some cases, differential reliance on bacterial intracellular factors suggested that even closely related phages may depend on distinct infection strategies, potentially involving phage-specific genes of unknown function. Our findings reveal key genetic dependencies shaping phage-host interactions and offer a framework for predicting infection outcomes in natural and applied settings. ### Competing Interest Statement The authors have declared no competing interest. Department of Energy and Environment, https://ror.org/05d5hbz44, #DE-SC0020173, #DE-SC0023307

1 day ago

#microsky #phagesky #phage

www.biorxiv.org/content/10.6...

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Q&A: What factors influence likelihood and severity of Ebola outbreaks? Researcher at Penn State discusses results of two papers that looked at factors that contribute to how Ebola virus disease outbreaks begin and how severe they become.

2 days ago

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We study pandemics, and the resurgence of measles is a grim sign of what’s coming Controlling the spread of many infections, including measles, depends on trust in public health, which is eroding.

2 days ago

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christoph_STCmicrobeblog

@christophstc.bsky.social

2 days ago

#MicroSky

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Current Research in Microbial Sciences

@microbesinfect.bsky.social

2 days ago

How are #kefir microbial communities & product characteristics maintained in industrial production?

Kefir’s complex microbial symbiosis drives flavor & health benefits but industrial methods dilute key functions. New synthetic cultures offer solutions
www.sciencedirect.com/science/arti... #MicroSky

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