#TGFbeta

pharmaphorum

@pharmaphorum.bsky.social

2 months ago

#JiangsuHengruiPharma has chalked up a first-in-class approval for retlirafusp alfa, a #bifunctionaldrug that targets #PDL1 and #TGFbeta, as a treatment for advanced #gastriccancer.

pharmaphorum.com/news/hengrui...

IRB Barcelona

@irbbarcelona.org

4 months ago

🗣️ Dr. @hoheyn.bsky.social (@cnag-ffm.bsky.social eu.bsky.social): “Applying state-of-the-art technology, we observed how #TGFbeta blocks #immunotherapy efficacy and identified new therapeutic targets to improve #ColorectalCancer treatments.”

IRB Barcelona

@irbbarcelona.org

4 months ago

On the one hand, #TGFbeta prevents a sufficient number of T lymphocytes (the cells responsible for eliminating #cancer cells) from reaching the tumour from the blood. On the other hand, it blocks the expansion of the few T cells that manage to infiltrate the tumour.

IRB Barcelona

@irbbarcelona.org

4 months ago

Published in @natgenet.nature.com, the study reveals how, via a hormone called #TGFbeta, colorectal tumours build a dual barrier that prevents cells from the immune system from acting against the #cancer.

Tim Springer Lab

@springerlab.bsky.social

4 months ago

🔬 Welcome to the Springer Lab

Follow along to see how structure, mechanics, and biology come together to shape life at the molecular level.

#Integrins #TGFbeta #Mechanobiology #StructuralBiology #Biophysics #Organoids #RegenerativeMedicine #SpringerLab

News Medical

@newsmedical.bsky.social

1 year ago

Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children Scientists reveal that reactivation of Epstein-Barr virus (EBV), driven by TGFβ-induced immune suppression, is a key driver of multisystem inflammatory syndrome in children (MIS-C) following COVID-19....

Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children 🚨🧬🧒 www.news-medical.net/news/2025031... #MISC #EpsteinBarr #TGFbeta #ChildHealth #Immunology #COVID19 #Pediatrics #Inflammation #Virus #SARSCoV2 @nature.com

Toril Holien

@torilhol.bsky.social

1 year ago

Looking forward to "BMPs in Bone Biology" next week! 🦴👩‍🔬
#BMP #TGFbeta
Please sign up and join us 👇

@drshasnain.bsky.social

1 year ago

#PhD #IBD #IntestinalFibrosis #ResearchOpportunity #TheUniversityofQueensland #TranslationalResearchInstitute #Australia #Brisbane #IL24 #TGFbeta #ScientificResearch
#MaterResearch #TRI #UQ

Savage-Dunn lab

@cswormlab.bsky.social

1 year ago

Lab members holding gifts from holiday party

Year's end thoughts: Amidst the challenges, 2024 has been a year of growth for the Savage-Dunn lab.
#celegans #tgfbeta #genetics
1/n

News Medical

@newsmedical.bsky.social

1 year ago

Heart failure triggers multimorbidity by altering stem cells, study reveals Researchers identified that heart failure (HF) promotes multimorbidity by altering hematopoietic stem cells (HSCs) to produce pro-inflammatory macrophages, increasing vulnerability in multiple organs....

Heart failure triggers multimorbidity by altering stem cells, study reveals 🚑🔬❤️ www.news-medical.net/news/2024052... #HeartFailure #Multimorbidity #StemCells #Inflammation #HealthResearch #CardiacHealth #TGFbeta #ChronicDisease

Savage-Dunn lab

@cswormlab.bsky.social

1 year ago

We're hiring! Our NIH R35 MIRA grant was funded! Trainees at all levels (postbacs, graduate students, technicians, postdocs) will be considered! If you're interested in #TGFbeta and #BMP signaling, #Celegans genetics, #lipid metabolism or host-pathogen response, DM or email