Latest posts tagged with #Targetome on Bluesky
#Targetome
SETD2 emerges as a chromatin regulator of iron metabolism, controlling IRP2 levels and ferroptosis sensitivity through epigenetic mechanisms 🧬⚙️
Details: www.maxapress.com/article/doi/10.48130/tar...
#ironaddict #details #metabolism
#Targetome
Zinc supplementation reduces COVID-19 mortality by half, with MT2A emerging as a key biomarker for metal stress and immune response 🦠⚡
Details: www.maxapress.com/article/doi/10.48130/tar...
#immuneresponse #metal #stress #zincsupplementation
#Targetome
New study in Nature Neuroscience reveals Fc effector function is crucial for lecanemab's amyloid clearance in Alzheimer's treatment.🧠✨
Details: www.maxapress.com/article/doi/10.48130/tar...
#alzheimer #naturelovers #neuroscience #effector
#Targetome
Mining TTD uncovers understudied target pairs ripe for combo therapy—data-driven map guides cheaper, smarter multi-drug shots. 🎯💊
Details: www.maxapress.com/article/doi/10.48130/tar...
#ttd #therapy #target
#Targetome
Targeting neddylation shows promise for metabolic disease treatment. Fine-tuning cullin 3 activity key for safe, effective therapies. 🔬💊
Details: www.maxapress.com/article/doi/10.48130/tar...
#metabolicdisease #promise #therapy #targeting
#Targetome
INKT cells uniquely bridge innate/adaptive immunity via CD1d/glycolipid recognition, offering promising off-the-shelf therapy for cancer/infections with low GVHD risk! 🧬💉
Details: www.maxapress.com/article/doi/10.48130/tar...
#recognition #therapy #infections
#Targetome
Two decades on, RNA has graduated from messenger to medicine, revolutionizing how we drug the undruggable. 🧬✨
Details: www.maxapress.com/article/doi/10.48130/tar...
#decades #rna #medicine
#Targetome
Ceramides predict heart risk solo; Zhang finds they hijack CYSLTR2/P2RY6, sparking plaque. Block the duo, cut inflammation, ignore lipids. 🫀🎯
Details: www.maxapress.com/article/doi/10.48130/tar...
#risk #inflammation #block
#Targetome
Silybin + carvedilol combo shows powerful synergistic effects against liver fibrosis by inhibiting Wnt4/β-catenin signaling in activated hepatic stellate cells! 🧬💊
Details: www.maxapress.com/article/doi/10.48130/tar...
#liverfibrosis #effect #combo
#Targetome
Alzheimer’s fails single-target fixes; letrozole-irinotecan duo rewires neurons, erasing mouse plaques. Cell study lights combo-therapy path. 🧠🔥
Details: www.maxapress.com/article/doi/10.48130/tar...
#singletarget #alzheimer #target #therapy
#Targetome
RNA drugs rewrite disease genes 💉 yet stability & delivery hurdles persist; nano-carriers & circRNA spark next-gen cures 🧬
Details: www.maxapress.com/article/doi/10.48130/tar...
#nextgen #drugs #genes #stability
#Targetome
Peroxisomes drive UCP1-independent heat via FASN-ACOX2 cycle, mmBCFA turnover. Cold redistributes FASN, coupling lipid synthesis to energy burn. 🌡️🔬
Details: www.maxapress.com/article/doi/10.48130/tar...
#instaenergy #synthesis #energyburn
#Targetome
Microglia tell astrocytes “step back” via Wnt signals, freeing synapses for pruning 🧠✨ Glia duet reshapes neural circuits beyond neurons.
Details: www.maxapress.com/article/doi/10.48130/tar...
#neuralcircuits #signals #duet #reshape
#Targetome
Limited single-gene drugs fuel combo therapies.🧬FDA approves some, but we need novel targets for true synergy.💊
Details: www.maxapress.com/article/doi/10.48130/tar...
#drugs #therapy #target
Is #targetome really a new, bona fide -omics term?
