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Webinar at EMBL-EBI: Automatic annotation systems in UniProt. 12 March 2026, 15:00-16:00 GMT

Webinar at EMBL-EBI: Automatic annotation systems in UniProt. 12 March 2026, 15:00-16:00 GMT

Webinar speakers (with headshots): David CJ Carpentier, Scientific Database Curator; Pedro Raposo, Senior Curator/Bioinformatician. EMBL-EBI

Webinar speakers (with headshots): David CJ Carpentier, Scientific Database Curator; Pedro Raposo, Senior Curator/Bioinformatician. EMBL-EBI

If you are interested in knowing how #UniProt uses automatic annotation tools to enrich its data, join our #webinar on 12 March: we will discuss the two main tools currently in use in the database, ARBA and UniRule.

Registration is free but essential: www.ebi.ac.uk/training/eve...

πŸ–₯️🧬

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Combining information from these structures with functional information from #uniprot and co-evolutionary information via #alphafold we found new FANCD2 interactors that utilize the same site

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(2/3) The work entitled β€œTfR1 deficiency beyond combined immunodeficiency. Pivotal role of mitochondrial function and iron-sulfur cluster biogenesis in disease pathogenesis” reports that disease-associated #TfR1 variants ( #Uniprot #P02786 ) are also linked with severe mitochondrial dysfunction.

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Graphics image showing webinar at EMBL-EBI about Exploring large-scale proteomics data in UniProt. The webinar will run on 12 February 2026 at 15:00 GMT. The speakers are Emily Bowler-Barnett and Aurelien Luciani. Image credit: Rebecca Nicholl, EMBL-EBI

Graphics image showing webinar at EMBL-EBI about Exploring large-scale proteomics data in UniProt. The webinar will run on 12 February 2026 at 15:00 GMT. The speakers are Emily Bowler-Barnett and Aurelien Luciani. Image credit: Rebecca Nicholl, EMBL-EBI

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Join our upcoming webinar to learn exploring and accessing large-scale #proteomics data in #UniProt. Registration is free but essential: www.ebi.ac.uk/training/eve...

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πŸ‘ Thanks to our collaborators and the Complex Portal community!

πŸ”— Explore: www.ebi.ac.uk/complexporta...

#ComplexPortal #ProteinComplexes #IntAct #UniProt #OpenScience #FAIRdata #EMBL_EBI 🎊

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πŸ‘©β€πŸ”¬ 𝐒𝐨 𝐭𝐑𝐒𝐬 𝐍𝐞𝐰 𝐘𝐞𝐚𝐫, let’s resolve not just to feel healthier, but to understand how our biology really works - guided by evidence, tools, and data that are openly accessible and citable. 🧠✨

#COMPLEXPORTAL #IntAct #UniProt #EMBLEBI #NEWYEAR2026

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πŸ‘ Huge thanks to UniProt for integrating the isoform information!

🀝 This was a joint curation effort by IntAct and UniProt, and a great example of collaborative science.
Here’s to an exciting year ahead! πŸš€πŸ§¬
tinyurl.com/N-terminal-p...

#EMBLEBI #IntActEBI #UniProt #Proteoforms

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#Biocuration is essential to transform unstructured biological data into machine-readable and structured resources. While institutional databases (e.g. #UniProt) can afford professional biocuration, many smaller initiatives rely on volunteer efforts (2/8).

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when you code over weekend and results are f*ck*ng awesome!!

#R #claude #perplexity
#TrEMBLE #uniprot #proteomes #taxonomic_divisions #fungi

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Database Tutorials Explore how to use BLAST, cBioPortal, PolyPhen-2, and UniProt - perfect for both classroom learning and independent projects.

πŸ‘©β€πŸ« πŸ’» STEM educators: How can your students gain experience with real-world #genomics data?

The Database Tutorials module provides guidance for using #BLAST, #cBioPortal, #PolyPhen-2 and #UniProt in classrooms or independent projects: www.jax.org/education-an...

#Dataskyence #EduSky

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UniProt UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.

(5/5) As a result, the work lead by Frederic and AntΓ²nia shed a bit more light on #COX4I1 ( #UniProt link β†’ www.uniprot.org/uniprotkb/P1... ), and its role in #LeighSyndrome, a condition that affects approximately 1 in 40,000 live births.

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Let’s make your science more FAIR - Findable, Accessible, Interoperable, and Reusable.
#Biocuration #FromBenchToDatabase #FAIRdata #ProteinInteractions #EMBL-EBI #IntAct-EBI #OpenScience #UniProt #DataMatters

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Hey #TeamMassSpec,

Many non-human proteomics studies still search against taxon-filtered FASTAs.

❌ Redundant sequences
❌ Inflated search space
βœ… Reference proteomes cut redundancy, improve annotation, and make results comparable.

πŸ‘‰ Time to move beyond taxon filters. #proteomics #massspec #uniprot

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Graphics image showing webinar at EMBL-EBI about "A guide to Uniprot for students". The webinar will run on 02 October 2025 at 15:00 BST.

Graphics image showing webinar at EMBL-EBI about "A guide to Uniprot for students". The webinar will run on 02 October 2025 at 15:00 BST.

Graphic showing  the speakers' photos and names, as well as their role at EMBL-EBI: David CJ Carpentier (Scientific Database Curator) and Paul Denny (Senior Database Curator)

Graphic showing the speakers' photos and names, as well as their role at EMBL-EBI: David CJ Carpentier (Scientific Database Curator) and Paul Denny (Senior Database Curator)

Join us on Thursday, 2 October for an introductory webinar on UniProt! We will explore the types of data available and how this data can be analysed to answer biological questions.

Register here: www.ebi.ac.uk/training/eve...

#UniProt #ProteinScience #UniProtWebsite #EMBLEBITraining #Webinar

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US genomics pioneer Paul Thomas joins SIB as Swiss-Prot co-director Paul Thomas joins Alan Bridge in leading SIB’s largest group, based in Geneva. As a pioneer in computational biology for genomics, principal investigator of a globally important resource on gene...

🧬 US genomics expert Paul Thomas joins SIB as Swiss-Prot co-director, with @alanbridge.bsky.social
πŸ” Leader in gene function research; among the world’s most-cited scientists
πŸ“Š His arrival strengthens SIB’s role in generating trustworthy, AI-ready biological knowledge #UniProt #GeneOntology
More πŸ‘‡

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UniProt: user benefits up to 39 times higher than operational costs Academic and private researchers using UniProt, a unique and high-quality knowledgebase for proteins co-developed by SIB, benefit from efficiency gains worth a combined €373-565 million each year. T...

#uniprot user benefits are estimates to be on the order of 20 times higher than operational costs www.sib.swiss/news/uniprot-user-benefi...

#infrastructure #opendata #curation #FAIRdata #proteins

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A short history of the UniProt RDF and SPARQL. After founding of UniProt in 2002, UniProt was available in #RDF since 2007, and has grown to a 225 billion statement/edge/triple knowledge graph queryable with #SPARQL

A short history of the UniProt RDF and SPARQL. After founding of UniProt in 2002, UniProt was available in #RDF since 2007, and has grown to a 225 billion statement/edge/triple knowledge graph queryable with #SPARQL

#UniProt The largest open+free #knowledgegraph in the life sciences. I will be talking about the why and the use cases at #semantics2025 5th of September 2025. Looking forward to seeing you all there!

2025-eu.semantics.cc/page/sessions

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🧬 MFM13 is now listed on UniProt as a disease variant linked to mutation in the HSPB8 gene.
Another step toward to better recognition and awareness of this ultra-rare HSPB8-related myopathy.
πŸ”— See section Disease&Variants on Uniprot
#MFM13 #HSPB8 #Uniprot #Myopathy

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New #publication from our network! Our partners at @fraunhoferitmp.bsky.social introduce the Knowledge Graph Generator (KGG) β€” an automated workflow for building disease-specific #KnowledgeGraphs using public data sources like #ChEMBL and #UNIPROT.

πŸ‘‰ academic.oup.com/bioinformati...

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The UniProt website API: facilitating programmatic access to protein knowledge. #UniProt #REST_API @narjournal.bsky.social‬ 🧬 πŸ–₯️
academic.oup.com/nar/advance-...

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protein structure in small window of bigger web page, no way to full size.

protein structure in small window of bigger web page, no way to full size.

#uniprot just hides the controls.. so you can't even try to full screen. but you can fortunately link out the #ebi #alphafold site where (ctd..)

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May is skin cancer awareness month! We're highlighting Telomerase holoenzyme complex (CPX-265) featuring TERT(UniProt:O14746). ComplexPortal: tinyurl.com/mt7u4wbs & visit UniProt for all melanoma-linked proteins tinyurl.com/mryjvyu7 #MelanomaAwareness, #ComplexPortal, #IntAct-EBI, #UniProt

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It is Skin Cancer awareness month! Explore manually curated interactomes of proteins associated with familial melanoma in IntAct. Access the network in IntAct (tinyurl.com/26tc7xtm). #IntAct-ebi, #ComplexPortal, #UniProt, #MelanomaAwareness, #HumanDisease, #SunSafety, #SpotSkinCancer,

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Very pleased that CD-Code is now cross-referenced by #UniProt and that we made it into the latest release: www.uniprot.org/release-note...

Browse our manually curated #condensates at: cd-code.org

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UniProt UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.

We're really excited that CD-CODE is now cross-referenced by #UniProt and has already been included in the latest release: www.uniprot.org/release-note...

Spreading knowledge about #biomolecular #condensates πŸ₯³

@ebi.embl.org @sib.swiss @mpi-cbg.de @tothpetroczylab.bsky.social @hymanlab.bsky.social

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Original post on akademienl.social

At @swat4hcls there was a presentation by @albdrg that I really like: https://www.youtube.com/watch?v=F4Nl-nmLZA4 This uses #SPARQL to combine data in a privacy aware #beacons-api and combine it with public #knowledgegraph like #uniprot by @SIB and #wikidata @wikidata to reduce cost of the data […]

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Screenshot showing the QLever SPARQL query editor, a federated query against the OMERO Knowledge Graph and the Uniprot SPARQL endpoint. Results show the OMERO well number, the taxon annotation, the corresponding scientific name and scientific names of hosted organisms.

Screenshot showing the QLever SPARQL query editor, a federated query against the OMERO Knowledge Graph and the Uniprot SPARQL endpoint. Results show the OMERO well number, the taxon annotation, the corresponding scientific name and scientific names of hosted organisms.

My #SPARQL query of the day: List all known organisms in the #uniprot taxonomy database for which the donor of a sample depicted in #OMERO
is a host. Promptly answered
by federating local #OMERO Virtual Knowledge Graph and https://sparql.uniprot.org/sparql I […]

[Original post on mastodon.world]

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An #ML pipeline
- to quantify similarities between human and animal protein targets
- using
1. protein 3D structure-based features from #PDB
2. nominal data from #UNIPROT
3. bioactivity data from #ChEMBL
- to identify optimum animal model for studying a target
πŸ‘‡

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(2/2) They investigated mitofusin 1 and mitofusin 2 proteins ( #UniProt #Q8IWA4 and #O95140) and their role in interorganelle communication and autophagy. Congratulations to the first author, Isabel Gordaliza, and the whole team behind this outstanding job. #IRBScience

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One Billion Biochemical RDF Triples! <p>That must be a record! Eric Jain wrote on <a href="http://lists.w3.org/Archives/Public/public-semweb-lifesci/">public-semweb-lifesci</a>:</p> <div class="language-plaintext highlighter-rouge"><div class="highlight"><pre class="highlight"><code>The latest release of the UniProt protein database contains just over a billion triples*! PRESS RELEASE :-) The data is all available via the (Semantic or otherwise) Web: http://beta.uniprot.org/ ...or can be bulk-downloaded from: ftp://ftp.uniprot.org/ * Counting some reification statements, and assuming no overlap between "named graphs". P.S. This should be the last you'll hear from me on this topic -- I'm off to new adventures... </code></pre></div></div> <p>I surely hope this is not the last we hear of this huge RDF collection.</p> <p class="post-meta"><i>This post was originally posted as https://chem-bla-ics.blogspot.com/2007/10/one-billion-biochemical-rdf-triples.html.</i></p>

a bit over 17 years ago: "One Billion Biochemical RDF Triples!" chem-bla-ics.linkedchemistry.info/2007/10/24/one-billion-b...

#semweb #uniprot

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