#Yap1

Antibodies.com

@antibodies-dot-com.bsky.social

3 months ago

Antibodies.com | Antibodies, Proteins, and ELISA Kits Antibodies.com supplies high-quality antibodies, proteins, and ELISA kits to life science researchers at cost-effective prices. Discover more, for less.

Using the phosphor-YAP1 (Ser128) antibody from antibodies.com, the group also revealed increased #YAP1 #phosphorylation in persister cells. We’re proud that our product, helped uncover the potential role of YAP-TEAD activity in supporting cell survival.

Barriga Lab

@eliasbarrigalab.bsky.social

5 months ago

Finally, our work reveals a hidden mechanical state of regeneration where tissue stiffening instruct cells to transit into regenerative states...

Far from perfect but always looking forward to hearing from you #Regeneration #Mechanobiology #Piezo1 #Yap1 #Xenopus #FrogPower #Morphogenesis

Barriga Lab

@eliasbarrigalab.bsky.social

5 months ago

... then we found that cells sense this stiffening via #Piezo1, which in turn activates #Yap1. This Piezo1–Yap1 cascade relays tissue mechanics into transcriptional programs that support the transition into regenerative bud states...

Olga Meiri Chaim #ScienceNotSilence #Hypersensory #MaskUP #Vax

@olgachaim.bsky.social

7 months ago

#YAP1 #SDC1 #proteoglycan #KRAS #glycotime #cancer
Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers.

Cell Chemical Biology

@cp-cellchembiol.bsky.social

1 year ago

The July Issue of @CellChemBiol is live! Read it here: http://dlvr.it/T9mKhz #smoothened #hedgehog #optogenetics #NaVs #Rho-GTPase #YAP1 #MesenchymalStemCells #K2Pchannels #PROTAC #deubiquitylase #chromatin #PARPinhibitors

Giorgio Seano

@giorgioseano.bsky.social

1 year ago

Luigi Luigidaweb GIF ALT: Luigi Luigidaweb GIF

We then deeply investigated the vulnerabilities and molecular regulators of VC-Resist with the hope of targeting this invasive and resistant cell state in the future. #YAP1 #FGFR1 (5/11)