#ZP2

Luca Jovine

@jovinelab.org

10 months ago

Ny forskning kan leda till hormonfritt preventivmedel Jakten på ett hormonfritt preventivmedel har pågått i många år. Nu har forskare på KI upptäckt ett sätt att stoppa befruktning med hjälp av antikroppar. – Det hade gett kvinnor möjligheten att själva ...

Thanks @svtnyheter.bsky.social for covering our #ZP2 non-hormonal #contraception story!

www.svt.se/nyheter/inri...

@ki.se
@esrf.fr
@pnas.org
@vetenskapsradet.bsky.social
@kawresearch.bsky.social

Luca Jovine

@jovinelab.org

11 months ago

Structural basis of ZP2-targeted female nonhormonal contraception | PNAS Monoclonal antibody IE-3 prevents mouse fertilization by binding ZP2, a major component of the oocyte-specific zona pellucida (ZP). We show that an...

Fresh off the press in @pnas.org: functional and structural studies of the interaction between #fertilization-blocking mAb IE-3 and mammalian #egg coat protein #ZP2

www.pnas.org/doi/10.1073/...

Thanks to
@vetenskapsradet.bsky.social @erc.europa.eu @embo.org @kawresearch.bsky.social @dfg.de

Luca Jovine

@jovinelab.org

1 year ago

Just in time for 8 March, we are thrilled to open the way to targeted non-hormonal contraception with the first structure of a fertilization-blocking antibody bound to a key female reproductive protein, #ZP2:

Structural basis of ZP2-targeted immunocontraception
www.biorxiv.org/content/10.1...

Luca Jovine

@jovinelab.org

1 year ago

Happy to bring the #ZP2 and egg coat filament story to HZB BESSY, where one the key datasets was collected!