Latest posts tagged with #apicaljunctions on Bluesky
Since epithelial #cytokinesis/abscission resolves at the level of #apicaljunctions, conditions where alpha-cat becomes persistently unfolded may interfere—and this could drive binucleation in cells that use this #polyploid state. 9/12
Curiously, LZTS2 localizes to #basal bodies #centrosomes #midbody BUT ALSO #apicaljunctions. LZTS2 was also enriched in two recent BioID screens with the AJ/TJ component Afadin (Manser and @peiferlabunc.bsky.social labs). So LZTS2 seemed like a good target. 7/12
