#bbot

@lilyluwhot.bsky.social

1 day ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/7pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️ ☮️🕊️ ☮️ ☮️

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Lilyluwhot

@lilyluwhot.bsky.social

1 week ago

#Purrs4Peace is in 1 hour at 3 pm EDT/7 pm UK! Join
@squirtthecat.bsky.social & me as we purr/woof/coo for a better world! Hop on Squirt's #Peacebus - ALL WELCOME! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #theaviators

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StockTitan

@stocktitan.net

1 week ago

BBOT Announces Publication in Cancer Discovery Highlighting Preclinical Data Demonstrating BBO-11818 is a Potent and Selective panKRAS Inhibitor BridgeBio Oncology Therapeutics (Nasdaq: BBOT) announced publication in Cancer Discovery of preclinical data for BBO-11818, a non‑covalent, orally bioavailable panKRAS inhibitor that binds KRAS in both ON and OFF states and shows activity across KRASG12D, G12V, and G12C mutants.Key facts: >500‑fold selectivity for KRAS over other RAS isoforms, robust monotherapy tumor inhibition in preclinical models across colorectal, pancreatic, and lung cancers, and a confirmed partial response (56% tumor reduction) in the ongoing Phase 1 KONQUER‑101 trial. Additional clinical data and an internal combination with BBO‑10203 are expected later in 2026.

#BBOT BBOT Announces Publication in Cancer Discovery Highlighting Preclinical Data Demonstrating BBO-11818 is a Potent and Selective panKRAS Inhibitor

www.stocktitan.net/news/BBOT/bbot-announces...

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StockTitan

@stocktitan.net

1 week ago

BBOT Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress BBOT debuted as a publicly traded oncology company developing a differentiated portfolio of three clinical-stage small molecule inhibitors targeting the RAS pathway. Announced encouraging preliminary safety and efficacy data across all three programs: BBO-8520’s differentiated efficacy and safety

#BBOT BBOT Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress

www.stocktitan.net/news/BBOT/bbot-reports-f...

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Lilyluwhot

@lilyluwhot.bsky.social

2 weeks ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️

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Lilyluwhot

@lilyluwhot.bsky.social

3 weeks ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join me, @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️PurrpurrPurr

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Lilyluwhot

@lilyluwhot.bsky.social

1 month ago

Purring with gratitude for the different groups that bring comfort to us as we miss newly OTRB furiends. Thank yoo #pawcircle #HealingPurrsPawty #BBoT & #PA for #Tributeride, #wlf10thbattalion #AngelGang & #TheAviators. Yoo all ROCK! #Purrs4Peace PurrpurrPurrpurrPurrpurrPurrpurrPurrpurrPurrpurrPurr

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Lilyluwhot

@lilyluwhot.bsky.social

1 month ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️PurrpurrPurrpurr

8 1 0 1

Lilyluwhot

@lilyluwhot.bsky.social

1 month ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @SquirtTheCat & da #peacecrew as we purr/woof/coo/tweet for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️

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Lilyluwhot

@lilyluwhot.bsky.social

1 month ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo/post for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️

4 1 0 0

Lilyluwhot

@lilyluwhot.bsky.social

1 month ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️PurrpurrPurrpurr

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Freshet News

@freshetnews.bsky.social

1 month ago

Clean Energy Summit 2026 2026 Clean Energy Summit BUY A TICKET NOW Day Hour Minute Second Burnaby isn’t just hosting the conversation on clean energy, we’re leading it. As a recognized centre for clean energy and climate inno...

The Burnaby Board of Trade has its Clean Energy Summit this month.

🎟️ www.bbot.ca/clean-energy...

#bbot #burnaby #cleanenergy #environment #business

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Lilyluwhot

@lilyluwhot.bsky.social

1 month ago

Purring with gratitude for the different groups that bring comfort to us as we miss newly OTRB furiends. Thank yoo #pawcircle #HealingPurrsPawty #BBoT & #PA for #Tributeride, #wlf10thbattalion #AngelGang & #TheAviators. Yoo all ROCK! #Purrs4Peace PurrpurrPurrpurrPurrpurrPurrpurrpurrPurrpurrPurrpurr

4 2 0 0

Lilyluwhot

@lilyluwhot.bsky.social

1 month ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️

4 1 1 0

Lilyluwhot

@lilyluwhot.bsky.social

2 months ago

Purring with gratitude for the different groups that bring comfort to us as we miss newly OTRB furiends. Thank yoo #pawcircle #HealingPurrsPawty #BBoT & #PA for #Tributeride, #wlf10thbattalion #AngelGang & #TheAviators. Yoo all ROCK! #Purrs4Peace PurrpurrPurrpurrPurrpurrPurrpurrPurrpurrPurrpurr

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Lilyluwhot

@lilyluwhot.bsky.social

2 months ago

Pls join us at #Purrs4Peace in 25 mins! Hop on SquirtTheCat.bsky.social 's #Peacebus & purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome to join da #PeaceCrew! PurrpurrPurrpurrPurrpurrPurrpurrPurrpurrPurr

6 1 1 3

StockTitan

@stocktitan.net

2 months ago

BBOT Announces New Clinical Data Advancing Its Portfolio of Three Innovative and Differentiated RAS and PI3Kα Pipeline Programs BridgeBio Oncology Therapeutics (Nasdaq: BBOT) reported preliminary Phase 1 safety and antitumor data across three oral RAS/PI3Kα programs: BBO-8520, BBO-11818, and BBO-10203. Key highlights include a 65% ORR (11/17) and 66% 6-month PFS in KRASG12C NSCLC with BBO-8520 monotherapy (data cutoff Nov 15, 2025), durable responses in combination with pembrolizumab, and responses in KRASG12C/STK11 and/or KEAP1 co-mutants. BBO-11818 showed a confirmed PR in pretreated PDAC with a 56% tumor reduction at higher dose levels (data cutoff Dec 10, 2025). BBO-10203 selected a 500 mg QD expansion dose, reported no hyperglycemia, and is advancing combination cohorts. Additional combination and expansion data expected H2 2026.

#BBOT BBOT Announces New Clinical Data Advancing Its Portfolio of Three Innovative and Differentiated RAS and PI3Kα Pipeline Programs

www.stocktitan.net/news/BBOT/bbot-announces...

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Lilyluwhot

@lilyluwhot.bsky.social

2 months ago

#Purrs4Peace is in 45 minutes at 3 pm EDT/8 pm UK! Join @squirtthecat.bsky.social & me as we purr/woof/coo for a better world! Hop on Squirt's #Peacebus - ALL WELCOME! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #theaviators PurrpurrPurrpurrPurrpurrPurrpurrPurr

9 2 3 1

Lilyluwhot

@lilyluwhot.bsky.social

2 months ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo/tweet for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️

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Lilyluwhot

@lilyluwhot.bsky.social

2 months ago

Please join us at #Purrs4Peace in 15 mins! Hop on @squirtthecat.bsky.social 's #Peacebus & purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome to join da #PeaceCrew! PurrpurrPurrpurrPurrpurrPurrpurr Purrpurr

13 4 0 0

Lilyluwhot

@lilyluwhot.bsky.social

3 months ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/8pm UK! Join @squirtthecat.bsky.social & da #peacecrew as we purr/woof/coo/tweet for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️

2 1 0 0

StockTitan

@stocktitan.net

3 months ago

BBOT Announces Late-Breaking Preclinical Data on BBO-10203, a First-in-Class RAS:PI3Kα Breaker, at the San Antonio Breast Cancer Symposium (SABCS) BridgeBio Oncology Therapeutics (Nasdaq: BBOT) announced late-breaking preclinical data on BBO-10203 at SABCS on Dec 10, 2025. Data show BBO-10203 is a first-in-class covalent RAS:PI3Kα breaker that binds PI3Kα at Cys242, blocks RAS-driven PI3Kα-AKT signaling, and produces dose- and time-dependent pAKT inhibition after oral dosing without inducing hyperglycemia in glucose tolerance testing.BBO-10203 demonstrated robust anti-tumor activity as monotherapy and combined with fulvestrant, ribociclib, trastuzumab or chemotherapy in preclinical breast cancer models. A Phase 1 trial (BREAKER-101; NCT06625775) is enrolling with initial Phase 1 data expected in first half of 2026.

#BBOT BBOT Announces Late-Breaking Preclinical Data on BBO-10203, a First-in-Class RAS:PI3Kα Breaker, at the San Antonio Breast Cancer Symposium (SABCS)

www.stocktitan.net/news/BBOT/bbot-announces...

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Lilyluwhot

@lilyluwhot.bsky.social

3 months ago

Pls join us at #Purrs4Peace in 30 mins! Hop on @squirtthecat.bsky.social 's #Peacebus & purr/woof/coo for peace! #wlf #zshq #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators #AnipalsofBluesky All Welcome to join da #PeaceCrew! PurrpurrPurrpurrPurrpurrPurrpurr

5 1 1 0

Lilyluwhot

@lilyluwhot.bsky.social

4 months ago

Pls join us at #Purrs4Peace in 45 mins at 3pm EST/8pm UK! Hop on @squirtthecat.bsky.social 's #Peacebus & purr/woof/coo for peace! #wlf #zshq #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome to join da #PeaceCrew! PurrpurrPurrpurrPurrpurrPurrpurr

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StockTitan

@stocktitan.net

4 months ago

#BBOT BBOT Reports Third Quarter 2025 Financial Results and Update on Corporate Progress

www.stocktitan.net/news/BBOT/bbot-reports-t...

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Lilyluwhot

@lilyluwhot.bsky.social

4 months ago

#Purrs4Peace is in 55 mins at 3 pm EDT/8 pm UK! Join
@squirtthecat.bsky.social & me as we purr/woof/coo for a better world! Hop on Squirt's #Peacebus-ALL WELCOME! #wlf #zshq #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #theaviators #anipalsofbluesky #catsofbluesky #dogsofbluesky

4 3 0 0

Lilyluwhot

@lilyluwhot.bsky.social

4 months ago

Pls join us at #Purrs4Peace in 15 mins! Hop on @squirtthecat.bsky.social #Peacebus & purr/woof/coo for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators #AnipalsofBluesky All Welcome to join da #PeaceCrew! PurrpurrPurrpurrPurrpurrPurr

2 1 0 0

StockTitan

@stocktitan.net

4 months ago

BBOT Announces Poster Presentations at the San Antonio Breast Cancer Symposium (SABCS) BridgeBio Oncology Therapeutics (Nasdaq: BBOT) announced two poster presentations at the San Antonio Breast Cancer Symposium (SABCS), Dec 9-12, 2025, in San Antonio, Texas. Both posters feature BBO-10203, described as a first-in-class, orally bioavailable, selective breaker of the RAS:PI3Kα interaction.Details: a Late-Breaking Pre-clinical poster (Abstract 3568, Presentation PS2-12-06) on Dec 10, 5:00–6:30 p.m. CT by Kerstin Sinkevicius, PhD, reports tumor growth inhibition alone and combined with fulvestrant or ribociclib without inducing hyperglycemia. A Trials-in-Progress poster (Abstract 203, Presentation PS5-07-06) on Dec 12, 12:30–2:00 p.m. CT by Andreas Varkaris, MD, PhD, outlines the phase 1a/1b BREAKER-101 study of BBO-10203 in advanced solid tumors.

#BBOT BBOT Announces Poster Presentations at the San Antonio Breast Cancer Symposium (SABCS)

www.stocktitan.net/news/BBOT/bbot-announces...

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Lilyluwhot

@lilyluwhot.bsky.social

4 months ago

Do yoo want to make the world a better place? #Purrs4Peace is at 3pm EST/7pm UK! Join @SquirtTheCat & da #peacecrew as we purr/woof/coo/tweet for peace! #wlf #zshq #fbjam #weeti #BBoT #PA #Tributeride #Pawgaritaville #HealingPurrsPawty #pawcircle #TheAviators All Welcome! ☮️💞 ☮️
UK pals pls note time!

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Lilyluwhot

@lilyluwhot.bsky.social

4 months ago

Purring with gratitude for the different groups that bring comfort to us as we miss newly OTRB furiends. Thank yoo #pawcircle #HealingPurrsPawty #BBoT & #PA for #Tributeride, #wlf10thbattalion #AngelGang & #TheAviators. Yoo all ROCK! #Purrs4Peace PurrpurrPurrpurrPurrpurrPurrpurrpurrPurrpurrPurrpurr

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Posts tagged #bbot