#cder

RinnLynn

@cder-indo.bsky.social

2 weeks ago

Would you wait till it gets bigger
#sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

13 2 0 0

RinnLynn

@cder-indo.bsky.social

3 weeks ago

Getting locked up in the hotel room, can someone come and help me? 🥺
#sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

14 2 1 0

RinnLynn

@cder-indo.bsky.social

1 month ago

This post is GEM certified 💎

#sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

17 3 0 0

RinnLynn

@cder-indo.bsky.social

2 months ago

Are my pussy beautiful 🥺?

#sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

33 8 1 0

RinnLynn

@cder-indo.bsky.social

2 months ago

Need someone that worthy enough to take the black Excalibur from my sissy ass

#sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

39 7 0 0

RinnLynn

@cder-indo.bsky.social

2 months ago

Am I cute?
ボク、カワイイ？🥺🥰
#sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

29 6 1 0

Helen Branswell 🇨🇦

@helenbranswell.bsky.social

3 months ago

FDA staff fear Tracy Beth Høeg will bring bias and instability to embattled drug center Høeg is set to become the fifth head of the FDA's drug center in a year.

Tracy Beth Høeg assumes the role of acting director of the #FDA's drugs division Monday. #CDER staff are worried about what Høeg will do. Among her targets: #RSV monoclonals that have been game changers, but which Høeg questions. @lizzylawrence.bsky.social reports. www.statnews.com/2025/12/11/t...

63 23 0 2

pharmaphorum

@pharmaphorum.bsky.social

4 months ago

FDA appoints veteran Pazdur to replace Tidmarsh The FDA has steadied the ship at CDER by naming veteran regulator Richard Pazdur as director, although he was reportedly reluctant to take the job

The #FDA has steadied the ship at #CDER by naming veteran regulator Richard Pazdur as director, although he was reportedly reluctant to take the job.
pharmaphorum.com/news/fda-app...

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RinnLynn

@cder-indo.bsky.social

4 months ago

Ready to serve you 😘😘
#sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

31 3 1 0

RinnLynn

@cder-indo.bsky.social

5 months ago

ummmm why you look so HOTTTT
#locktober #sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl #hentai

26 4 0 0

40:40 Recruitment - celia@4040recruitment.co.uk

@4040rec.bsky.social

5 months ago

FDA pilots fast-track scheme for US-made generics In another effort to boost domestic drug manufacturing, the FDA is piloting fast-track reviews for generics tested and made in US facilities.

#generics #FDA #pharmamanufacturing #importedmedicines #fasttrackreviews #bioequivalencetesting #APIs #drugmanufacturing #patientaccess #pharmaceuticalmanufacturing #pharmaceuticalproduction #CDER #manufacturingofmedicines #FDAPreCheck #pharmamanufacturingfacilities
zurl.co/yuskn

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RinnLynn

@cder-indo.bsky.social

5 months ago

Are you brave enough to replace the plug with your HARD thing? 😜
#locktober #sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl

44 6 0 0

RinnLynn

@cder-indo.bsky.social

5 months ago

Just a few days left... oh wait, fucccc-
#locktober #sissy #femboy #cder #crossdresser #男の娘 #hentai #ts #tsgirl

52 5 0 0

RinnLynn

@cder-indo.bsky.social

5 months ago

Ready for locktober 😁
#locktober #femboy #sissy #chastity #ts #tgirl #nsfw #cder #cderindo #男の娘 #女装

21 3 0 0

BioMassSpec

@realbiomassspec.bsky.social

5 months ago

Metabolomic signatures in adults with metabolic syndrome indicate preclinical disruptions in pathways associated with high-density lipoprotein cholesterol, sugar alcohols - Cardiovascular Diabetology – Endocrinology Reports Background Metabolic syndrome is a pressing public health issue and risk factor for the development of type 2 diabetes (T2D) and cardiovascular disease (CVD), yet clinical practice is lacking in biomarkers that represent pre-clinical perturbations of the heterogenous subtypes of risk. This study aimed to characterize the baseline metabolome in relation to known clinical characteristics of risk in a sample of obese adults. Methods Untargeted metabolome data from N = 126 plasma samples with baseline data from a previously completed study including obese adults with metabolic syndrome. Metabolites were acquired using validated liquid chromatography mass spectrometry methods with 15–25 internal standards quantified by peak heights. Pearson’s correlations were used to determine relationships between baseline metabolites, sample characteristics (e.g., age, body mass index (BMI)), and atherosclerotic clinical characteristics (e.g., high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), triglycerides), adjusting for multiple comparisons using the Benjamini–Hochberg False Discovery Rate (FDR) method. Differences in metabolite levels between clinical classifications of dysglycemia (e.g., normal, prediabetes, diabetes) at baseline were assessed using ANOVA and adjusted for multiple comparisons and adjusted for covariates. Results The sample consisted primarily of female (74%) participants, predominantly white (70%), with an average age of 56 years. After FDR adjustment, two baseline metabolites were significantly associated with age (xylose, threitol), two with BMI (shikimic acid, propane-1,3-diol), one with LDL (tocopherol-alpha), and 42 with HDL cholesterol. Three metabolites were significantly associated with fasting blood glucose (FBG) levels at baseline (glucose, gluconic acid lactone, pelargonic acid). Conclusions This study identified novel metabolite associations with known markers of T2D and CVD risk. Specific metabolites, such as alpha-tocopherol, branched-chain amino acids (BCAAs), and sugar-derived metabolites like mannose and xylose, were significantly associated with age, BMI, lipid profiles, and glucose measures. Although most sample participants had normal HDL cholesterol at baseline, 42 metabolites including branched chain amino acids were significantly associated with HDL, suggesting pre-clinical perturbations in biological pathways associated with both diabetes and cardiovascular comorbidities. Metabolomic signatures specific to prediabetes and metabolic syndrome can enhance risk stratification and enable targeted prevention strategies for T2D. Longitudinal studies are needed to understand how these associations change over time in at-risk individuals compared with controls.

Metabolomic signatures in adults with metabolic syndrome indicate preclinical disruptions in pathways associated with high-density lipoprotein cholesterol, sugar alcohols #CDER #MassSpec clindiabetesendo.biomedcentral.com/articles/10....

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RinnLynn

@cder-indo.bsky.social

5 months ago