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Posts tagged #directedevolution

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In planta directed evolution: Turning a single leaf into a laboratory of quasi-infinite variants | Plantae Directed evolution aims to identify variants of a gene of interest (GOI) with improved or novel functions by accelerating mutation and selection under experimental conditions. However…

📄🌿 PSRW summary

In planta directed evolution: Turning a single leaf into a laboratory of quasi-infinite variants

🔗 plantae.org/in-planta-di...

#PlantaePSRW #PlantScience #DirectedEvolution

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🔥Hot Off the Press | GRAPE: #DirectedEvolution in #Plants
A #Science study shows GRAPE enables fast, versatile directed evolution in planta. Evolved NLR NRC3 escapes nematode inhibition; rice NLR Pikm-1 recognizes 6 AVR-Pik alleles. Boosts plant breeding.
ow.ly/ZlMQ50XyUek

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Rapid and scalable platform enables directed evolution in plant cells Directed evolution is a laboratory technique that mimics natural selection and allows scientists to evolve genes and the proteins they encode. Traditionally, this technique has been used in microbes, mammalian cells, or in test tubes.

✨Scientists are *evolving* genes in the lab! 🧬 Mimicking nature's power to create & refine proteins.🤯 What will they engineer next? #DirectedEvolution

Source: phys.org/news/2025-10-rapid-scala...

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Our new paper on AI-generated TrpBs with @anima-anandkumar.bsky.social. GenSLM generated very useful promiscuous TrpB #enzymes, bypassing a lot of #directedevolution! great work by the whole team, especially Theophile Lambert. www.biorxiv.org/content/10.1...

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📅July 7-11
The 2025 Onassis Lectures in Biology and Chemistry will be held @forth-ite.bsky.social, Heraklion, Crete. This year’s Lectures are devoted to the advances, challenges, and future prospects of #Re-engineeringBiology through #DirectedEvolution and #Synthetic cellular pathways.

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Research Position (PhD) in organic chemistry and b... <div style="text-align: justify;">The&nbsp; research&nbsp; group&nbsp; „Organic&nbsp; Chemistry&nbsp; and&nb...

Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry.
🙏 RETWEET (We want to recruit internationally)

Organic chemistry meets #DirectedEvolution
Highly interdisciplinary & passionate research group

uni-bielefeld.hr4you.org/job/view/433...

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Ammonia is key to fertilizers and essential to feed the world.🌍Its industrial production consumes ~2% of the global energy.
In this fully funded PhD project, you'll combine #enzymedesign and #directedevolution to turn nitrogen into ammonia.💡🌱

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A huge thanks to my past and present group members, mentors, and collaborators who have supported this journey!

#Biocatalysis #EnzymeEngineering #Photoenzymes #SustainableChemistry #DirectedEvolution #ComputationalBiology #ProteinDesign #Hiring #PhDPositions

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Three PhD positions | Computational protein design Three PhD postiions in computational protein design

🌍 Exciting news! This summer, my group joins @mpimicrobiomarburg.bsky.social l to create photoenzymes for solar energy conversion & carbon capture. With #ProteinDesign 🖥️ & #DirectedEvolution 🧬, we’ll push enzyme design to new limits for a sustainable future!

#Hiring www.mpg.de/24336572/phd...

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‘Need for speed: high throughput’ – mass spectrometry approaches for high-throughput directed evolution screening of natural product enzymes Covering: 2015 to 2024Mass spectrometry (MS)-based methods have been implemented extensively for enzyme engineering due to their label-free nature, making them suitable for screening a wide range of b...

Check out our new review we wrote with @shaunmckinnie.bsky.social @robbieshepherd.bsky.social pubs.rsc.org/en/content/a... looking at the interface of MS for screening large mutant libraries like those associated with #directedevolution @ucscscicomm.bsky.social

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Very relevant to #DirectedEvolution and what transition vs. transversion mutations do if they happen at the 2nd base.

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New paper from our lab @elife.bsky.social . We show how #DirectedEvolution reshaped #CRISPR for expanding DNA recongition.
This is work by Kazi Hossain, an incredibly talented student visiting my lab from the Czub lab, now in Orozco's lab & Lukasz Nierzwicki.
doi.org/10.7554/eLif...

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We have a great PhD program across many disciplines, including #proteinengineering, #directedevolution, #machinelearning, #biocatalysis, #enzymes, and much more.

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This is a very good, succinct description of the problem! I gave it to my group to read. #directedevolution #enzymes #AI4proteins

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