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Synapse: Your Connection to our MSK Authors
Meet: Elisa De Stanchina
Research Focus: Res Facilities; Lab Member

Trastuzumab deruxtecan resistance via loss of HER2 expression and binding
synapse.mskcc.org/synapse/work...

#TrastuzumabDeruxtecan #HER2
#BreastCancerResearch #TargetedTherapy #Oncology

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Call for Papers: This Special Collection examines clinical and translational developments in high‑risk HER2+ early breast cancer, including response‑adapted strategies, ADCs, and biomarker‑guided approaches. buff.ly/3jv7zmw #BreastCancer #Oncology #HER2 #MedOnc #ClinicalTrials

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Nuestro póster destaca cuatro clases terapéuticas clave en oncología:
🔬 #ADC (conjugados anticuerpo-fármaco)
🎯 Terapias dirigidas a #HER2
🧬 Inhibidores de #CDK4/6
💊 Inhibidores de #PARP

#CancerDeMama #Oncología #InnovacionFarmaceutica #Farmaceutica #SaludGlobal #DengYueMedicinasEnHongKong

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Dr. Dennis Slamon's Inspiration Behind "Living Proof" | Stand Up To Cancer
Dr. Dennis Slamon's Inspiration Behind "Living Proof" | Stand Up To Cancer YouTube video by Stand Up To Cancer

Dr Dennis Slamon's journey as the pioneer of Herceptin, inspires a movie of his life, "Living Proof."

Dr. Dennis Slamon's Inspiration Behind "Living Proof" | Stand Up To Cancer

youtube.com/watch?v=vsa7...

YouTube, Stand Up To Cancer

#Herceptin #HER2

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📊 En este póster compartimos 5 empresas biofarmacéuticas chinas líderes en innovación contra el cáncer de mama y algunas de sus terapias clave.
💬 ¿Conocías alguna de estas compañías?

#CáncerDeMama #ADC #HER2 #InhibidoresCDK46 #InnovaciónEnSalud #DengYueMedicinasEnHongKong

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China impulsa la innovación en oncología.
📊 Descubre en este póster 5 medicamentos innovadores para el cáncer de mama.

#CáncerDeMama #Dalpiciclib #Pyrotinib #Chidamide #Envafolimab #DisitamabVedotin #HER2 #HER2Positive #TargetedTherapy #ADC #TerapiasInnovadoras #DengYueMedicinasEnHongKong

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Ther Adv Med Oncol: Real‑world pyrotinib beyond progression vs rechallenge in HER2+ mBC (incl. brain mets): PFS2 ~7.2 vs 6.3 mo (NS); OS 31.6 vs 21.0 mo (trend). CNS subgroup also benefited. Read: 【🔗https://buff.ly/xsK4lFw#BreastCancer #HER2 #BrainMets #Oncology

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💊FDA Approval Update | #HERNEXEOS® (#zongertinib tablets): the first targeted therapy for #HER2 mutant advanced #NSCLC
🔹For adults as an initial treatment option
🔹11% of patients with a complete response
🔹65% of patients with a partial response

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Zongertinib Approved by FDA for HER2+ NSCLC Zongertinib receives FDA accelerated approval for advanced HER2-mutant NSCLC, expanding targeted treatment options.

Zongertinib Receives FDA Accelerated Approval in HER2-Mutant NSCLC

oncodaily.com/oncolibrary/...

#OncoDaily #Oncology #Cancer #Health #Medicine #NSCLC #MedEd #MedOnc #MedNews #LungCancer #HER2 #TargetedTherapy #FDAApproval

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Analysis of 346 BCBM cases from the GEICAM RegistEM registry reveals faster CNS progression and poorer survival in TNBC and HER2+ subtypes, with major differences between de novo vs subsequent brain metastases.
🔗 buff.ly/74yHwuH
#BreastCancer #BrainMets #HER2 #TNBC #RealWorldEvidence

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Lung Cancer Targeted Therapies OncTalk 2026 {{MetaTags.description}}

Register:
give.cancergrace.org/event/lung-c...

Support free patient education 💙 #LungCancer #EGFR #HER2

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Diagnostic value of peripheral blood inflammatory indices for breast cancer grade and immunohistochemical markers: a retrospective observational study - BMC Cancer Introduction Breast cancer remains a leading global health burden with rising incidence, particularly in low- and middle-income countries. Emerging evidence suggests that systemic inflammatory indices...

Neutrophil-to-lymphocyte ratio (NLR) shows moderate value in predicting #BreastCancer grade and #HER2 status — a simple, low-cost blood marker with potential for early risk stratification.
#Oncology #Biomarkers #NLR link.springer.com/article/10.1...

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Synapse: Your Connection to our MSK Authors
Meet: Sohrab Prakash Shah
Research Focus: BIOSTAT/EPIDEMIOLOGY; Chief Attending

Determinants of sensitivity to HER2-targeted antibody drug conjugates in urothelial cancer
synapse.mskcc.org/synapse/work...

#UrothelialCancer #BladderCancer #HER2

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Preclinical studies of BB-1701, a HER2-targeting eribulin-containing ADC with potent bystander effect and ICD activity Statement of Significance: A HER2-targeting eribulin-containing ADC had exhibited good plasma stability; BB-1701 had potent antitumor activities against mu

Antibody Therapeutics(IF=4.5, Oxford University Press)
📢📢Preclinical studies of BB-1701, a HER2-targeting eribulin-containing ADC with potent bystander effect and ICD activity
academic.oup.com/abt/article/...
#ADC #HER2 #Antibody

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ctDNA findings from the Ni‑High phase Ib trial: ERBB2 focal amplification and early mMAF decline strongly predict improved outcomes with trastuzumab + nivolumab + chemo in HER2+ aGC.
🔗https://buff.ly/S2kBuFe
#GastricCancer #HER2 #ctDNA

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第一三共、エンハーツが中国でHER2陽性胃がん二次治療に承認──DESTINY-Gastric04に基づく | STELLANEWS.LIFE STELLANEWS.LIFE(ステラニュース・ライフ)は、科学や技術、医薬品分野における最新の研究成果や発見 | STELLANEWS.LIFE(ステラニュース・ライフ)は、科学や技術、医薬品分野における最新の研究成果や発見

第一三共、エンハーツが中国でHER2陽性胃がん二次治療に承認──DESTINY-Gastric04に基づく
ENHERTU (trastuzumab deruxtecan) approved in China for second-line HER2-positive gastric cancer based on DESTINY-Gastric04

stellanews.life/technology/8...

#GastricCancer #HER2 #ENHERTU #AntibodyDrugConjugate #DESTINYGastric04

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【第一三共、HER2陽性胃がん二次治療で中国承認】

✔ トラスツズマブ前治療後のHER2陽性進行・再発胃がんで承認
✔ 第3相DESTINY-Gastric04に基づく判断
✔ 画期的治療薬指定・優先審査の下で取得

トラスツズマブ デルクステカン(商品名エンハーツ)は抗HER2抗体薬物複合体。中国では三次治療で条件付き承認済みで、今回は二次治療に拡大。生存期間など詳細指標は本発表では限定的であり、追加データの確認が必要。
#胃がん #HER2 #抗体薬物複合体

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When first-line cancer treatment stops working, knowing your options and speaking up matters. This man shares his experience with second-line HER2 therapy, biopsy decisions, and why self-advocacy can shape your care journey. #CancerCare #SelfAdvocacy #HER2 #PatientEmpowerment #Oncology

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Triple HER2 Blockade With Trastuzumab, Pertuzumab, and Pyrotinib Versus Dual HER2 Blockade in the Neoadjuvant Treatment of HER2‐Positive Breast Cancer: A Randomized, Phase II Study Triple HER2 blockade with trastuzumab, pertuzumab, and pyrotinib (TPPy) did not improve total pathological complete response (tpCR) rates or breast pathological complete response (bpCR) rates compare....

#Article in @MedComm_MC
Triple #HER2 Blockade With #Trastuzumab, #Pertuzumab, and #Pyrotinib Versus Dual HER2 Blockade in the #Neoadjuvant Treatment of HER2-Positive Breast Cancer: A Randomized, Phase II Study doi.org/10.1002/mco2...

#ClinicalTrial

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Zanidatamab (Baihe’an®): Un avance clave en el cáncer de vías biliares HER2 positivo

📩 info@dengyuemed.com
🔗https://dengyuepharma.com

#Zanidatamab #BaiheAn #HER2 #BiliaryTractCancer #Oncology #BispecificAntibody #TargetedTherapy #BreakthroughTherapy #CSCO #CDE #FDA

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#brca #hereditarycancer #genetics #patientexperience
#EarlyDetection #her2 #prostatecancer #breastcancer #cysticfibrosis #sicklecell #heartdisease #diabetes #pancreaticcancer

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Bridgy Fed Bridgy Fed is a bridge between decentralized social networks like the fediverse, Bluesky, and web sites and blogs.

fed.brid.gy/bsky/globalv...

#HER2 #NEU
headlines-world.com/advanced-sea...
ПЛАЖА ЈУТА
multi-search-tag-explorer.headlines-world.com/advanced-sea...
#MIROSLAV #BENKA
multi-search-tag-explorer.headlines-world.com/advanced-sea...
aepiot.com

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La #FDA a accordé la désignation de "thérapie révolutionnaire" au #Sévabertinib pour le traitement de 1ère intention des patients atteints de #CancerDuPoumon non à petites cellules non réséquable ou métastatique présentant des mutations activatrices #HER2
www.targetedonc.com/view/fda-gra...

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Join Rachna Shroff, MD, MS, FASCO at an ASCO GI 2026 satellite symposium exploring HER2-positive GI cancers, from molecular testing to targeted therapy across gastric/GEJ, CRC, and biliary tract cancers.

👉 Register: https://bit.ly/48FksQl

#ASCOGI2026 #HER2 #GICancers

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The role of HER2 in advanced bladder cancer is rapidly expanding.

📖 Read the full clinical thought commentary for expert perspectives on testing strategies, treatment sequencing, and future directions in HER2-positive urothelial carcinoma: https://bit.ly/4pIHX11

#HER2 #BladderCancer

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Lunit SCOPE Achieves Remarkable Concordance with Pathologists in HER2 Analysis for Advanced Biliary Tract Cancer A recent study shows Lunit SCOPE's AI technology aligns closely with pathologists in HER2 interpretation, advancing cancer diagnostics for biliary tract cancer.

Lunit SCOPE Achieves Remarkable Concordance with Pathologists in HER2 Analysis for Advanced Biliary Tract Cancer #South_Korea #Seoul #Lunit #HER2 #Biliary_Cancer

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🎙️ New episode: HER2 Uncovered – From Low to Ultralow
A/Prof Ben Dessauvagie & Prof Gelareh Farshid explore HER2 ultralow breast cancer, evolving pathology practice and implications for MDT decision-making.
🎧 Listen now: t.ly/3E4kJ | #BeyondtheSlide #HER2 #HER2Ultralow #Oncology#MedEd #BreastCancer

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Join Matthew Gubens, MD, MS, FASCO and Estelamari Rodriguez, MD, MPH this Tuesday for a 1-hour expert discussion on the latest insights in HER2-altered NSCLC.

A concise, practical session designed to support real-world decision-making 👉 https://bit.ly/451c6QE

#MedicalEducation #CME #NSCLC #HER2

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💊FDA Approval Update | #Hyrnuo (#sevabertinib)
🔸For #HER2-mutant non-small cell lung cancer #NSCLC
⚙️Reversible tyrosine kinase inhibitor targets #EGFR and #HER2 protein
🌟MedChemExpress provides #Sevabertinib for research use.

#NSCLC #TyrosineKinaseInhibitor #TKI #FDA #FDAApproval

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The #FDA has given accelerated approval to #Bayer for oral #HER2 tyrosine kinase inhibitor sevabertinib as a second-line treatment for advanced HER2-mutant #NSCLC, allowing it to challenge #BoehringerIngelheim's recently approved Hernexeos.

pharmaphorum.com/news/bayer-t...

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