Human-focused life sciences are moving from vision to implementation.
#betterscience is #humanrelevant
Huge thanks to all the brilliant participants 👏
safermedicines.org/royal-societ...
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#humanrelevant
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Posts tagged #humanrelevant
Registration for live-stream closes Monday 2nd Feb. On-demand recording will be available soon.
#betterscience is #humanrelevant
royalsociety.org/science-even...
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Figure 1 from the linked paper showing a ‘Schematic representation of in silico methods across the rare disease therapeutic pipeline.’ The caption reads: “Methods span from diagnosis (e.g., variant analysis) to drug discovery (e.g., virtual screening), preclinical development (e.g., disease modeling), and clinical trials (e.g., virtual patients, pharmacokinetics/ pharmacodynamics (PK/PD) modeling). Abbreviations: PBPK physiologically based pharmacokinetics, popPK population pharmacokinetics, HTS, high-throughput screening, QSAR quantitative structure–activity relationship.”
🖥️ #InSilico tech is revolutionizing #RareDisease research! 🦓
Computational models, machine learning, and digital twins can:
✅ Integrate complex data
✅ Simulate biology
✅ Predict actionable outcomes
#HumanRelevant 🧪 🧬
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The Alliance for Human Relevant Science welcomes the government's roadmap to phase out animal testing. We are ready to help deliver and accelerate this vital transition. #betterscience #humanrelevant
www.humanrelevantscience.org/replacing-an...
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The time may come when we look back and realise that animal experiments have been a huge and costly distraction, a path we might have done better to completely avoid.
#betterscience
#humanrelevant safermedicines.org/blog_post/mi...
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A graphic with a photo of a white and grey rat standing up but slightly crouching in front of a geometric blue and yellow background. The text reads: “Business Wire. October 7, 2025. “This advance demonstrates the ability of Human-on-a-Chip systems to replicate complex neurological processes such as stress-related cognitive decline without the need for animal studies.” James Hickman, PhD. Chief Scientist, Hesperos.
🤝 Hesperos, Inc. and Bayer teamed up to create the first-ever human microphysiological system that can model central nervous system stress.
Read the paper by Autar et al. 👇
doi.org/10.1016/j.bi...
#neuroskyence #invitro #mps #organonchips #brainonachip #NAMs #humanrelevant 🧪
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It’s time for the research community to move away from animal models and invest fully in #HumanRelevant science—approaches that use human cells, tissues, and data.
Expand this thread for some highlights of human-based #HIVResearch 👇
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Sign and share this petition to make sure animal testing is REALLY phased out in the UK! #betterscience #humanrelevant you.38degrees.org.uk/petitions/a-...
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Patients would benefit from human-relevant science in place of preclinical animal tests that risk incorrect predictions of safety and efficacy. #betterscience #humanrelevant safermedicines.org/blog_post/on...
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UK government needs to quickly up its game, or be left in the dirt by the forward-thinking US FDA, NIH and EPA, who now realise that #betterscience is #humanrelevant
safermedicines.org/blog_post/as...
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Rather than try to create a “mouse model” of Tourette Syndrome, as has been done for years, scientists at Yale University conducted an animal-free study by examining human brain tissue. #animals #humanrelevant #Tourette
www.elsevier.com/about/press-...
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Experimental methods that don’t use animals, like tissue chips and computational models, lead to the development of safer and more effective therapies and pharmaceuticals.
#betterscience #humanrelevant
utahnewsdispatch.com/2025/04/16/k...
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The FDA is phasing out animal testing for therapies like monoclonal antibodies, pushing for human-relevant “NAMs” like organ-on-a-chip, AI toxicity models & human cell assays. A huge shift we’ve long championed at MIMETAS.
🔗 Read the announcement: www.fda.gov/news-events/... #HumanRelevant
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30 Wochen #Einsamkeit im #Mäusekäfig? Solche #Tierversuche sind unnötig! Eine Studie mit 42.000 Menschen zeigt: Einsamkeit hinterlässt Spuren im Blut – eine Erkenntnis gewonnen ganz ohne #Tierleid. Wer den #Menschen verstehen will, muss auch am Menschen #forschen. #Humanrelevant statt #grausam!
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Animal tests are notoriously bad at identifying liver-toxic drugs. Now is the time to implement predictive complex in vitro models of human livers into routine drug testing #betterscience #humanrelevant
www.frontiersin.org/journals/dru...
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“I’m not a mouse, I’m not even a monkey,” she says. “When we are doing drug testing in animals, and then we take it into a clinical trial in humans we see a lot of drugs fail.” #betterscience #humanrelevant
www.theguardian.com/environment/...
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“We’re not going to be able to replace animals in biomedical research with the meager investments that federal agencies are now making.”
#betterscience #humanrelevant
thehighwire.com/news/house-o...
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The time has come for a decisive shift away from animal testing and toward technologies that prioritize accuracy, facilitate precision medicine and establish more humane research practices #betterscience #humanrelevant
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"In order to successfully tackle cancer, we must embrace its complexity, prioritize prevention, and transition to innovative research methods that use human-focused models"
#betterscience #humanrelevant
www.scienceadvancement.org/reflections/...
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