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Posts tagged #hyperphosphorylation

Infographic showing how altered microRNA expression contributes to Alzheimer’s pathology — promoting amyloid-beta plaques, neurofibrillary tangles, neuroinflammation, and neuronal apoptosis in the hippocampus

Infographic showing how altered microRNA expression contributes to Alzheimer’s pathology — promoting amyloid-beta plaques, neurofibrillary tangles, neuroinflammation, and neuronal apoptosis in the hippocampus

In #Alzheimer dysregulated #microRNAs influence key #pathological features —
🧩 #Aβ plaque buildup
🧩 #Tau #hyperphosphorylation & neurofibrillary tangles
🧩 #Neuroinflammation & apoptosis in the hippocampus

Understanding these miRNA shifts opens doors to early diagnosis & targeted therapies.

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#Microhaemorrhages are common . intranasal #SARSCoV2 infection caused #microgliosis, #tau #hyperphosphorylation & α-synuclein pathology in 🐹 cortex even without CNS infection. Notably, the pathology persisted beyond #viralpersistence which could have implications for #longCOVID & #neurodegeneration

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