#ipscells

3 days ago

💉 What if diabetes patients never had to inject insulin again?
Japan's Orizuru Therapeutics completed the world's first transplant of iPS cell-derived islet cells. A woman with 20+ yrs of Type 1 diabetes received treatment in Feb 2025.
#iPSCells #RegenerativeMedicine #Diabetes

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1 week ago

🧬 HISTORIC: Japan approved the world's first iPS cell therapies as products.
"ReHeart" — cell sheet repairing damaged hearts
"Amshepri" — dopamine neurons for Parkinson's
20 years from Yamanaka's Nobel discovery to real medicine.
#iPSCells #StemCell #RegenerativeMedicine

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First-of-a-kind stem-cell therapies set for approval in Japan Regenerative medicines are headed for people with Parkinson’s disease or severe heart failure — but researchers are concerned about minimal clinical-trial data.

1 week ago

Nature comment: two first #iPSCells medicines got conditional approval after treating only 7–8 patients

Smart acceleration or risky precedent?

buff.ly/2PgcKWj

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1 week ago

📣 📣 📣 World first!!

Japan’s health ministry has granted a provisional 7-year approval for the commercialization of two regenerative medicine products derived from #iPSCells, aimed at treating ischemic cardiomyopathy and Parkinson’s disease.
buff.ly/nAKKmib

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1 week ago

🧬 Why are human legs longer than arms, but chimps have the opposite?
Kyoto & Hiroshima Univ. grew the world's first ape limb precursor cells from iPS stem cells — bonobos, chimps & gibbons.
Their "Whole-Zoo iPS Project" turns zoos into genetic libraries.
#iPSCells #StemCell

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2 weeks ago

👁️ World first: Japan begins clinical trials for corneal regeneration using donor-derived iPS cells.
Reimei, an Osaka University spinoff, is testing iPS cell sheets to restore sight. If it works, this could end the global cornea donor shortage.
#iPSCells #RegenerativeMedicine

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3 weeks ago

🧬WORLD FIRST: Japan approves 2 iPS cell products
🫀ReHeart: cardiac sheets for heart failure
🧠Amshepri: cell transplant for Parkinson's
20yrs after Yamanaka's Nobel discovery, iPS cells finally reach patients.
What's regen medicine like in YOUR country?
#iPSCells #iPS

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BioInformant - Stem Cell Industry News

3 months ago

Pierre Savatier discussing his recent results on inter-species chimeras, including those based on rabbit blastocysts, and based on primate (human and non-human) naive #iPSCells.

#FSSCR2025
✨🔬 Exciting #StemCell science ahead!
Lyon, Nov 17–19, 2025

Full program here 🫵
buff.ly/kLeH5ET

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@bioinformant.bsky.social

6 months ago

About Event | iPSC Drug Development Summit The 5th iPSC Drug Development Summit is the longest-standing and most comprehensive meeting focused exclusively on iPSC-derived therapies

I'm excited to announce the 5th iPSC Drug Development Summit (Oct 1–2, 2025, Boston), the industry’s leading forum advancing iPSC-derived therapies hosted by Hanson Wade.

ipsc-therapies-summit.com/about/about-...

#ipscells #drugdiscovery #drugdevelopment

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RichardJR

@electricbluesfan.bsky.social

6 months ago

14/16 Future approaches promise even greater precision.

Stanford researchers combine induced pluripotent stem cells with CRISPR gene editing to create scalable tissue replacements.

CRISPR offers more targeted correction than viral gene addition, with fewer side effects.

#CRISPR #iPSCells

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News Medical

@newsmedical.bsky.social

10 months ago

iPS cell transplants show early promise for treating Parkinson's disease safely In a first-of-its-kind human trial, researchers transplanted iPS-cell-derived dopaminergic progenitors into patients with Parkinson’s disease and observed promising motor improvements with no serious ...

iPS cell transplants show early promise for treating Parkinson's disease safely 🧠🧬💉 www.news-medical.net/news/2025042... #Parkinsons #StemCells #RegenerativeMedicine #Neuroscience #CellTherapy #iPSCells #Dopamine #Neurodegeneration #TranslationalResearch @nature.com

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1 year ago

Extensive pre-clinical testing of the safety and efficacy of midbrain dopaminergic cells derived from clinical-grade human #iPSCells lines, paving the way for an autologous clinical trail in Parkinson's disease. Harvard Medical School.
#CellTherapy
https://buff.ly/4ia51Se

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1 year ago

Wow! Another phase III clinical trial using #iPSCells derived cells, for Parkinson's disease.

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1 year ago

Allogeneic CAR NK cells derived from #iPSCells in lymphoma (phase I trial): safe and impressive results for follicular lymphoma, as well as for relapsed LBCL after autologous #CARTcells.
Towards a ready-to-use CART treatment?

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BioInformant - Stem Cell Industry News

1 year ago

Autologous #iPSCells production at Cira for $316,000, and 50x less in 10 years.

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@bioinformant.bsky.social

1 year ago

This is exciting progress to see for #ipscells!

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Shicheng Guo

@shihcheng.bsky.social

1 year ago

Two-year safety outcomes of iPS cell-derived mesenchymal stromal cells in acute steroid-resistant graft-versus-host disease - Nature Medicine Sustained safety outcomes were seen at 2-year follow-up after induced pluripotent stem cell-derived mesenchymal stromal cell infusion in 15 individuals with steroid-resistant acute graft-versus-host…

In a 2-year follow-up of a trial on iPS cell-derived MSCs for steroid-resistant acute graft-versus-host disease, 60% of 15 participants survived, highlighting its potential. #iPScells #GvHD PMID:38778211, Nat Med 2024, @NatureMedicine

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1 year ago

First-in-human using allogeneic #iPSCells in four patients with cornea defect (limbal stem-cell deficiency LSCD)! And it works! No clinical rejection, disease stage had improved, and visual acuity was enhanced. A larger clinical trial is planned.
In the Lancet
https://buff.ly/4fhik2f
#CellTherapy

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2 years ago

Rabbit naive #iPSCells can colonize rabbit blastocysts and create highly chimeric rabbit fetuses. A new tool to study the determinant of embryonic colonization-competence. By Nathalie Beaujean, Pierre Savatier, Marielle Afanassieff and colleagues.
t.co/4itGOlLK93

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