Day 3 of the #GRC on #microproteins #darkproteome with a lively discussion on mega big data analyses for human #ncORFs #sORFs! What a great group!!
11
1
1
0
#ncORFs
Latest posts tagged with #ncORFs on Bluesky
Trending
Posts tagged #ncORFs
Summary of the ORFs in this catalog
tl;dr
This is a new authoritative catalog of #ncORFs for your #darkproteome research. We have updated many features, and expanded substantially from the original release. You can choose to use either a Comprehensive and Primary set.
This catalog will be supported by #GENCODE in forthcoming updates.
2
0
1
0
Length distribution of the Primary set ncORFs
Yet, we know this is ongoing work. The Primary set is biased: it's got an overrepresentation of very short ncORFs, most of which are uORFs.
Still, our goal is to democratize work on these #ncORFs, so that you can pick either the Comprehensive or Primary sets based on your needs.
0
0
1
0
Type and distribution of ncORFs in this set
The Comprehensive Set includes >28,000 ncORFs. Notably, we now expand this reference catalog to include many of the most interesting #ncORFs that have been overlooked:
- nonAUG ORFs, such as those using CUG, GUG and UUG start codons
- tiny ORFs that are 15 codons or less.
0
0
1
0
An overview of defining all ncORFs and the Primary set of ncORFs with enriched features.
We take the output of 9 prominent #Riboseq analyses and systematically map them to #GENCODE v45. We develop two concepts for your use:
- Comprehensive set: all high-quality #ncORFs
- Primary set: #ncORFs with metrics similar to protein-coding genes.
0
0
1
0
Congrats @simonelsasser.bsky.social and so excited to see this work in print!
#genomics
#bioinformatics
#RNAsky
🔎 #microproteins
🧬 💻
#RiboSeq
#ncORFs
5
1
0
0
Speaker list for the 2025 Gordon Research Conference on Microproteins
If you are excited about the #darkproteome. If you want to delve into #ncORFs and #RiboSeq, then this is the meeting for you!
Check out the speaker list. 🤩
0
0
0
0