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Kickstarting the 2026 Reina Lab retreat with a good dose of #nightscience courtesy of Dr. Wayne Beach, an expert (human) Conversation Analyst, under the premise - can we leverage human interaction analysis frameworks to think outside the box in cellular communication? … food for thought

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This is unpublished but I don't really care - was my favorite! I think that's the best way to do science!

Amazing talk this morning 🎉
@odedrechavi.bsky.social @itaiyanai.bsky.social
#NightScience

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79 | Maria Leptin and creativity in grant writing - Night Science Maria Leptin is the President of the ERC, the European Research Council, and Professor of genetics at the University of Cologne. In this episode, Maria describes her own path as one driven by observat...

What is actually a high-risk, high-gain project proposal?
Great to hear the answer directly from the ERC president Maria Leptin.

🎧 nightscience.buzzsprout.com/1744020/epis...

Night Science (@nightsciencepod.bsky.social) is simply an amazing podcast for scientists!

#ERC #NightScience #GrantWriting

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Two heads are better than one, unless you’re a land planarian trying to find some grub. FORCE pilot project - check!

Video credit: Daniel Stoga

#nightscience
#WormWednesday
@hanhtkvu.bsky.social
@aikmi.bsky.social @embldbunit.bsky.social
@martaalvarez.bsky.social

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New book "Transdicourse 3: Women in Art, Science and Body Politics" is out - edited by the wonderful Jill Scott. In our chapter "Conversations in the Space of Art-Science Practice" Helen Pynor and I explore spaces, even the more "messy" ones, where art and science meet. #nightscience #dayart

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This deserves a #NightScience tag

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@itaiyanai.bsky.social #nightscience ✌️✊🙏

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Itai Yanai - Deutsch-Amerikanisches Institut. Haus der Kultur. Why do we humans no longer have a tail? An analysis of the human genome came to the conclusion that …

🧬 Why don’t humans have tails? Find out tonight at 8 PM with @itaiyanai.bsky.social
The Gorilla 🦍 in the Genome explores curiosity-driven science & breakthroughs in genetics.
📍 Geist Heidelberg | 🎟️ Tickets: dai-heidelberg.de/en/events/it...
#NightScience #Discovery #ScienceFestival

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Update: The messy middle meets ‘Night Science’ Exploring an exciting meta-science movement...

#newpost, exploring an exciting meta-science movement called #nightscience! Thanks @marymirvis.bsky.social for the resource!

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#nightscience needs some #young #blood -when you ask for #establishment for #ideas -one gets #established #ideas!!

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Phenomenal talk this morning 🤯🔥
#Nightscience

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I love the idea of #NightScience. But in terms of explaining the origins of ideas (also great), what if you don't know where an idea came from? Sometimes there's a "eureka" moment that can be recalled, but other times, the origin of an idea can be unclear. But we need to talk about this...

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Shop - Night Science By purchasing our merch you are supporting the Night Science Institute's mission - thank you! Our merch partner, FII Marketing, produces items on-demand in the United States and Canada, and uses union...

#NightScience merch has dropped! We have tees, a hat, a mug, some stickers - show your Night Science pride and support the Institutes mission at the same time! Don't be the last one in your lab ... 😊

night-science.org/home/about-u...

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Can creativity in science be learnt? These researchers think so Time pressure gets in the way of ideas. Developing ‘creative oases’ and small grants for risky ideas can encourage innovative thinking in science.

Can #creativity be learnt? A Nature Careers feature on Night Science featuring our Founders @itaiyanai.bsky.social and @martinlercher.bsky.social investigates this issue at the heart of #NightScience

www.nature.com/articles/d41...

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Scientific bedlam at the world’s weirdest and wildest research conference Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.

So mainstream media is covering #NightScience conferences now?? 🤔
www.nature.com/articles/d41...

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Bring On The Night
Bring On The Night YouTube video by The Police - Topic

The website now includes a #NightScience section with all publications & projects dedicated to scientific adventures & side hustles... Inspired by @itaiyanai.bsky.social & @martinlercher.bsky.social of course 😉
www.uni-potsdam.de/en/specbioca...
www.youtube.com/watch?v=YVgW...

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Just came back from what might actually be the most unusual, brilliant, and delightfully crazy scientific gathering on this planet: Woodstock of Biology 2 + Night Science. | Daniel Żarski Just came back from what might actually be the most unusual, brilliant, and delightfully crazy scientific gathering on this planet: Woodstock of Biology 2 + Night Science. We rode trains into the woo...

Just came back from what might actually be the most unusual, brilliant, and delightfully crazy scientific gathering on this planet: Woodstock of Biology 2 + Night Science.

Read more 👇👇

#WoodstockBio2 #NightScience #TCTeAC #ScienceCanBeMagic #ReproDevoFish

www.linkedin.com/posts/daniel...

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#TCTeAC - the Woodstock of Biology2 & #nightscience - was such an amazing event!! We met great scientists who creatively presented their high quality work. We dreamt and discussed in a very broad, open-minded setting. Talking science outside of our nutshell can be soo valuable - let's do this again!

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#fightforsciemce at #TCTeAC with #nightscience :) cell & gene people gather together.

(no scientist got hurt)

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#nightscience at #TCTeAC, hence the umbrella

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After a great day 1, looking forward to day 2 of #WoodstockOfBiology #NightScience

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Original post on fediscience.org

“Night science is the creative side of the scientific process” — what does that mean?

Recently, I learned about this lecture series about “Night Science” and the creative process from the wonderful @HeidiSeibold !

Coined, apparently, by Jacques Monod, “Day Science” is the scientific process we […]

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I’d like to begin by congratulating my fellow graduates in the Rockefeller Class of 2015. I’m proud to be among you, and as one of your peers there’s obviously not much I can say to you by way of advice. But I can address the important people seated with you, your parents and family. If they’re like mine, they’re probably wondering what exactly their son or daughter has been doing for the past five to seven years. 

Every path through a PhD is different. From a variety of experiences and educational backgrounds in Applied Physics or Zoology, we arrive here from the world over, don a white lab coat, and call ourselves scientists. Invariably, we all feel like impostors at first. Entering a busy laboratory, it is easy to feel overwhelmed, surrounded by people who know what they're doing, while you expend every ounce of mental effort trying to follow along. But this disorientation is by design. It is in truth, the first real taste of freedom. There are no departments here to define ourselves by, classes are minimal, and the support, from the Dean’s office, the library, or student housing, is so extraordinary, that your next experiment is your sole focus. You are encouraged to learn science the best possible way: by doing it, from day one, your curiosity all the fuel you’ll need. 

For there is a simple truth behind what a PhD means here, and that is learning how to ask questions. And if I may, I’d like to posit that one question stands out as a key foundation, one that animates every scientist in this room on a daily basis, one that is the source of many of our adventures. It is the first question I asked here in earnest, and it is one that all of us scientist or not, can relate to. Here it is:

“How do we know that?” 

I was in Bob Darnell’s office in my first year when I asked it. Bob had presented to the first year as part of the Seminars in Modern Biology. It’s one of only two mandatory courses here, and it consists entirely of Rockefeller faculty presenting their

I’d like to begin by congratulating my fellow graduates in the Rockefeller Class of 2015. I’m proud to be among you, and as one of your peers there’s obviously not much I can say to you by way of advice. But I can address the important people seated with you, your parents and family. If they’re like mine, they’re probably wondering what exactly their son or daughter has been doing for the past five to seven years. Every path through a PhD is different. From a variety of experiences and educational backgrounds in Applied Physics or Zoology, we arrive here from the world over, don a white lab coat, and call ourselves scientists. Invariably, we all feel like impostors at first. Entering a busy laboratory, it is easy to feel overwhelmed, surrounded by people who know what they're doing, while you expend every ounce of mental effort trying to follow along. But this disorientation is by design. It is in truth, the first real taste of freedom. There are no departments here to define ourselves by, classes are minimal, and the support, from the Dean’s office, the library, or student housing, is so extraordinary, that your next experiment is your sole focus. You are encouraged to learn science the best possible way: by doing it, from day one, your curiosity all the fuel you’ll need. For there is a simple truth behind what a PhD means here, and that is learning how to ask questions. And if I may, I’d like to posit that one question stands out as a key foundation, one that animates every scientist in this room on a daily basis, one that is the source of many of our adventures. It is the first question I asked here in earnest, and it is one that all of us scientist or not, can relate to. Here it is: “How do we know that?” I was in Bob Darnell’s office in my first year when I asked it. Bob had presented to the first year as part of the Seminars in Modern Biology. It’s one of only two mandatory courses here, and it consists entirely of Rockefeller faculty presenting their

work to students as they sort out which lab to join. I arrived mainly interested in the cell biology of viruses with the terrific capacity invade cells many times their size and make us sick, from the common cold to Ebola. How did they manage that? However, Bob’s presentation was on a disease called paraneoplastic neurodegeneration and the role of a protein called NOVA in regulating RNA splicing in the brain…he might as well have been speaking in ancient Greek. What’s worse, I’m quite sure I fell asleep. The only thing I recall was him mentioning one of my favorite books on science, Arrowsmith by Sinclair Lewis, which was roughly based on the Rockefeller Institute in its early days. This prompted me to write him an email, and I soon found myself in his office learning what the lab was up to at a more relaxed pace so I could understand. <Lab description> And so I asked “How do we know that?” Without hesitation, Bob fired up his computer and showed me the data. He revealed to me a new cartography of our genomes, that long list of instructions that makes a person, with stunning depth and clarity. It dawned on me that I could take the solutions in one lab and bring them to address scientific questions I was interested in.  After our discussion, which lasted the better part of two hours, I asked to rotate in his laboratory. I had found a mentor. 

“How do we know that?” It’s a powerful question for 5 words. It’s powerful precisely because it takes any explanation or observation and immediately, instinctively even, holds it up to scrutiny. No explanation for the workings of nature is immune to this question. And note that a satisfactory answer to this question is never “we know because I said so,” no matter who is speaking. Only verifiable experiment and careful observation can answer it. The egalitarian quality of this question contributes to a unique culture here. At Rockefeller, you’re surrounded by world-class professors, physicians, postdocs and staff, all of whom

work to students as they sort out which lab to join. I arrived mainly interested in the cell biology of viruses with the terrific capacity invade cells many times their size and make us sick, from the common cold to Ebola. How did they manage that? However, Bob’s presentation was on a disease called paraneoplastic neurodegeneration and the role of a protein called NOVA in regulating RNA splicing in the brain…he might as well have been speaking in ancient Greek. What’s worse, I’m quite sure I fell asleep. The only thing I recall was him mentioning one of my favorite books on science, Arrowsmith by Sinclair Lewis, which was roughly based on the Rockefeller Institute in its early days. This prompted me to write him an email, and I soon found myself in his office learning what the lab was up to at a more relaxed pace so I could understand. <Lab description> And so I asked “How do we know that?” Without hesitation, Bob fired up his computer and showed me the data. He revealed to me a new cartography of our genomes, that long list of instructions that makes a person, with stunning depth and clarity. It dawned on me that I could take the solutions in one lab and bring them to address scientific questions I was interested in. After our discussion, which lasted the better part of two hours, I asked to rotate in his laboratory. I had found a mentor. “How do we know that?” It’s a powerful question for 5 words. It’s powerful precisely because it takes any explanation or observation and immediately, instinctively even, holds it up to scrutiny. No explanation for the workings of nature is immune to this question. And note that a satisfactory answer to this question is never “we know because I said so,” no matter who is speaking. Only verifiable experiment and careful observation can answer it. The egalitarian quality of this question contributes to a unique culture here. At Rockefeller, you’re surrounded by world-class professors, physicians, postdocs and staff, all of whom

are your immediate peers. We share this beautiful campus, run into each other on the way to lunch or a lecture, and rub shoulders over drinks at the Faculty and Student’s Club, where there is little pretense between a Nobel prize winner and a first year student. That is because you are encouraged to question and to doubt, in the service of a better verifiable explanation. This refreshing attitude pervades campus life, such that on a daily basis it’s not President Tessier-Lavigne, Dean Strickland, or Professor Vosshall; it’s Marc, Sid, and Leslie. A fierce curiosity for the natural world is the only badge that is truly required. 

This curiosity led me to find the right virus to study, which brought me to Charlie Rice’s lab. And one meeting with Bob and Charlie together was all it took, I now had two outstanding mentors. Far from them balking at the idea of an untested first year graduate student taking on an independent project, bridging two laboratories, and requiring biochemical and computational skills he did not possess, they said go for it. Their trust showed me that they are as much students as I am. 

By asking “how do we know that?” we jolt ourselves into thinking, both critically and creatively, because the answer is often “we don’t”. And that’s okay. In fact that’s good. That’s when “How do we know that?" transforms into “How could we know that?” which we use to test made-up explanations known as hypotheses. It’s a call to action that is usually followed by its famous cousins “I wonder what would happen if…” and later “Are you seeing what I’m seeing?” I know I’m not alone in saying that these questions help form the daily backbone of working on a PhD. Doubt plus curiosity is a powerful combination. 

Now, contrary to what you might think, I don't want it seem as if science is an all-encompassing panacea for every question worth asking. Knowledge is not the same as wisdom. Part of the reason "How do we know that?" is such an important question to ask in

are your immediate peers. We share this beautiful campus, run into each other on the way to lunch or a lecture, and rub shoulders over drinks at the Faculty and Student’s Club, where there is little pretense between a Nobel prize winner and a first year student. That is because you are encouraged to question and to doubt, in the service of a better verifiable explanation. This refreshing attitude pervades campus life, such that on a daily basis it’s not President Tessier-Lavigne, Dean Strickland, or Professor Vosshall; it’s Marc, Sid, and Leslie. A fierce curiosity for the natural world is the only badge that is truly required. This curiosity led me to find the right virus to study, which brought me to Charlie Rice’s lab. And one meeting with Bob and Charlie together was all it took, I now had two outstanding mentors. Far from them balking at the idea of an untested first year graduate student taking on an independent project, bridging two laboratories, and requiring biochemical and computational skills he did not possess, they said go for it. Their trust showed me that they are as much students as I am. By asking “how do we know that?” we jolt ourselves into thinking, both critically and creatively, because the answer is often “we don’t”. And that’s okay. In fact that’s good. That’s when “How do we know that?" transforms into “How could we know that?” which we use to test made-up explanations known as hypotheses. It’s a call to action that is usually followed by its famous cousins “I wonder what would happen if…” and later “Are you seeing what I’m seeing?” I know I’m not alone in saying that these questions help form the daily backbone of working on a PhD. Doubt plus curiosity is a powerful combination. Now, contrary to what you might think, I don't want it seem as if science is an all-encompassing panacea for every question worth asking. Knowledge is not the same as wisdom. Part of the reason "How do we know that?" is such an important question to ask in

science, is because it’s easy to spot when it no longer applies. Standing in front of the many works of art that adorn this campus, this question is all but useless. It is utterly, perhaps comically, inept while falling in love.

This question makes it clear that science is a means, a way of looking at the world, and should not be confused with being an end unto itself. And here again our question has something to offer, because it is best phrased as "how do WE know that?" As a distinctly human creation, science is a great big "WE.” It is less a collection of facts and figures than a riveting history of brave souls who've asked "how do we know that?" devised an experiment, and shared the results with others. It is a history of invention and entrepreneurship, of engagement with public leadership to action, of articulating the need for research, of pointing out uncomfortable truths, and of providing life-saving cures. This is the legacy we formally inherit today, and it hinges on a great responsibility: for as much as we learn to doubt by asking “how do we know that?”, we have an equal if not more pressing responsibility to inspire everyone to ask it. What makes “how do we know that?” so special is that it is the best of Socratic doors. It’s an invitation to bring others in close, to show, to teach, and to nurture face-to-face the very human desire to know.

And so, friends and family, I have a challenge for you. Ask your son or daughter, or their advisor, or a passerby later at the reception, who’s carrying and constantly glancing at a timer. They’re probably a student or postdoc in the middle of an experiment, enjoying a brief snack. Ask them what they work on. And when they make a declaration on their subject, ask them, “how do we know that?” I guarantee that the first response is likely to be “it’s complicated,” but if you wait, the follow-up response can move you. And if they're really good, you might just want to head to the lab to ask and see for yourself.

science, is because it’s easy to spot when it no longer applies. Standing in front of the many works of art that adorn this campus, this question is all but useless. It is utterly, perhaps comically, inept while falling in love. This question makes it clear that science is a means, a way of looking at the world, and should not be confused with being an end unto itself. And here again our question has something to offer, because it is best phrased as "how do WE know that?" As a distinctly human creation, science is a great big "WE.” It is less a collection of facts and figures than a riveting history of brave souls who've asked "how do we know that?" devised an experiment, and shared the results with others. It is a history of invention and entrepreneurship, of engagement with public leadership to action, of articulating the need for research, of pointing out uncomfortable truths, and of providing life-saving cures. This is the legacy we formally inherit today, and it hinges on a great responsibility: for as much as we learn to doubt by asking “how do we know that?”, we have an equal if not more pressing responsibility to inspire everyone to ask it. What makes “how do we know that?” so special is that it is the best of Socratic doors. It’s an invitation to bring others in close, to show, to teach, and to nurture face-to-face the very human desire to know. And so, friends and family, I have a challenge for you. Ask your son or daughter, or their advisor, or a passerby later at the reception, who’s carrying and constantly glancing at a timer. They’re probably a student or postdoc in the middle of an experiment, enjoying a brief snack. Ask them what they work on. And when they make a declaration on their subject, ask them, “how do we know that?” I guarantee that the first response is likely to be “it’s complicated,” but if you wait, the follow-up response can move you. And if they're really good, you might just want to head to the lab to ask and see for yourself.

As new PhDs graduate, I'm reflecting on the below convocation address I delivered at my own PhD ceremony about science's most essential question: "How do we know that?" Equal parts #NightScience meditation and a call to action. Sometimes we need to hear from our younger selves. #StandUpForScience

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When the sun sets, the real explorers come out. Armed with a headlamp and curiosity, I hunt insects in the dark—then record every creeping detail in My Science Diary. Science begins with observation. Adventure begins at night. 🎥🐛 #CreepyWorldVR #NightScience #GatewayScience #vr #vrchat #insects

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"Night Science" – Wie die VolkswagenStiftung Freiraum für kreatives Denken schafft | VolkswagenStiftungSchließenWeiterWeiter Wissenschaft braucht Kreativität – doch im Forschungsalltag fehlt dafür oft der Raum. Mit dem neuen Förderangebot "Night Science" will die VolkswagenStiftung das ändern. Warum und wie unkonventionelle...

„It takes two to think!“ 🤝 Wir fördern mit #NightScience Wissenschaftler:innen-Tandems, die kreative neue Wege beschreiten wollen.

📅Stichtag: 5. Juni 2025
🎤 im Interview👇: Warum und wie fördern wir „Shower Thoughts“?

Wann bekommst du die besten Ideen?

#Wissenschaft #Forschung #CreativeThinking

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Had an absolute blast at the @mskcancercenter.bsky.social PDA Night Science event w/ @itaiyanai.bsky.social —improv exercises, big ideas, & a glimpse into the brilliant future of science! A pleasure to be hosted for such an inspiring and fun evening. #NightScience #FutureOfScience

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Just had a #NightScience call practicing day & night language. I am waiting for my neighbors to call the cops while overhearing sentences like "I give candies & w**d to the students so they graduate" (not advised for PIs). What the heck I am talking about? Come find out this Friday at MSK. #creative

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Woodstock.Bio2 + Night Science 2025 | Courses & Meetings

What else? #NightScience Continuing the tradition of the "Woodstock of Biology" #physiologicalirrelevantconference #conferencetoendallconferences because we like how it sounds. Science IS under siege, let's have fun & show the world we're still here (4/7)
woodstock.img.cas.cz

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Three pairs of earring-sized plastic tryptophan models. Each pair consists of L-tryptophan (left) and D-tryptophan (right).
All pairs have hydrogens shown in light green and nitrogen shown in light blue. One pair has dark purple carbon and orange oxygen; another pair has magenta carbon and silver oxygen; and the third pair has hot pink carbon and light purple oxygen.

Three pairs of earring-sized plastic tryptophan models. Each pair consists of L-tryptophan (left) and D-tryptophan (right). All pairs have hydrogens shown in light green and nitrogen shown in light blue. One pair has dark purple carbon and orange oxygen; another pair has magenta carbon and silver oxygen; and the third pair has hot pink carbon and light purple oxygen.

#TryptophanWednesday: the next enantiomearrings are, of course, trippy tryptophan.

Still dialing in the colors; it needs to be...trippier.

Luckily, it's a quick print, so it's easy to run tests between the day prints and the overnight prints. #NightScience indeed.

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At lab meeting today, attempting to stimulate more #nightscience, trainees started with failed or weird experiments, sparking an amazing discussion, contributions from every lab member and tonnes of new ideas and hypotheses. This will be a thing going forward. @itaiyanai.bsky.social

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