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Guérisons extraordinaires: quand les cas exceptionnels font progresser la recherche médicale Les cas de guérisons extraordinaires, du VIH ou d’autres maladies comme le cancer, représentent un miracle pour les patients concernés, mais intéressent aussi la recherche qui y voit l’espoir de nouve...

🌟 "Guérisons extraordinaires: quand les cas exceptionnels font progresser la recherche médicale."

🌟 "Extraordinary cures: when exceptional cases drive medical research forward."

#HIV
#VIH
#Mélanome métastatique
#metastatic melanoma
#Phagothérapie
#Phagotherapy

Good news as well as some hope

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Proud to be an  “Inauguration Committee Member“ of the new @ESCMID study group for Non-traditional Antibacterial Therapy #ESGNTA that will focus on the development of #phagetherapy #phagotherapy in Europe!

x.com/ESCMID/status/…

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Moreover an update about the current use and indication of #phagetherapy #phagotherapy in patients with #boneandjointinfection #BJI such as #prostheticjointinfection #PJI managed @CHUdeLyon @CrioacLyon will be done during this national congress!

x.com/CrioacLyon/sta…

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Yesterday, a 18th patient has been treated by #phagotherapy @CHUdeLyon using ultrasound-guided injection of a #bacteriophage cocktail for a complex #MRSA #prosthetic #knee #infection! Here we try to tackle antimicrobial resistance #AMR with #phages!

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Today, a 17th patient has been treated by #phagotherapy @CHUdeLyon🇫🇷 by a personalized #bacteriophage cocktail for a Staphylococcus epidermidis relapsing prosthetic joint infection ➡️ Phage discovery in Bern🇨🇭+ purification in Brussels🇧🇪 = incredible collaborative academic work!

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Six accepted abstracts about #phagetherapy #phagotherapy and #bacteriophagelysins #lysins at the next #eccmid2020 in #Paris! Lyon and our team @CrioacLyon @CIRI_Lyon @CHUdeLyon @UnivLyon1 are ready to integrate this incredible therapy to fight #antimicrobialresistance!🔥

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Our vision in Lyon about #phagetherapy #phagotherapy 2.0 ➡️ the time has come to determine if #phages have the ability to ⤴️⤴️⤴️ the clinical success rate in severe bacterial diseases ➡️ bone and joint infections #bji are definitely the optimal first candidates for that!

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Next saturday, the European culture channel @ARTEen will broadcast this film directed by Jean Crépu about the story of #bacteriophage and #phagotherapy partially shoted at @CrioacLyon @CHUdeLyon @CIRI_Lyon. Many thanks to Jean and also to our patients for their participation!

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Prophages are more frequent in nature than lytic #bacteriophages. They not destroy bacteria and could protect them from phagocytosis (See ➡️ it is required to check prophages during the production of #phages used for #phagotherapy!

cell.com/cell-host-micr…

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What a pleasure to meet today Saima Aslam @DocSaimaAslam @IPATH and Jason Gill @jason_j_gill @TAMU_CPT (on my ⬅️) after their very nice talks about #bacteriophages @IDWeek2019, with Pr. @rannirpaz1 from #HadassahMedicalCenter (on my ➡️). Nice academic forces for #phagotherapy!

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Maybe one day we can say that to patients with complex #infections. Indeed, #phagotherapy has a high potential, but it absolutely requires for safety tricky and costly good manufacturing practice production (GMP) of #bacteriophages

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Conclusion of the @ansm CSST: All the issues raised by #phagotherapy led to promote the establishment of a national platform for guidance and validation of the use of #phages to control their use in France and could eventually work on the implementation of an academic production

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Last week, two other patients received @CRIOAcLyon @CHUdeLyon a personalized GMP #bacteriophage therapy produced by #pherecydespharma, in conjunction with @ANSM, for complex S. aureus and S. Lugdunensis prosthetic joint infections. Thanks for your precious help 🤞! #phagotherapy

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